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Context: The age-related decline in dehydroepiandrosterone (DHEA) levels is thought to be of importance for general and vascular aging. However, data on the association between DHEA and mortality are conflicting. Objectives: We tested the hypothesis that low serum DHEA and DHEA sulfate (DHEA-S) levels predict all-cause and cardiovascular disease (CVD) death in elderly men. Design, Setting, and Par
BACKGROUND:: Exposure to second-hand smoke has been shown to be associated with increased cardiovascular mortality in several, but not all, epidemiologic studies. Our aim was to investigate the risk of circulatory death associated with exposure to second-hand smoke in never-smokers in a very large prospective study, the European Prospective Investigation into Cancer and Nutrition. A secondary aim
Apelin, a recently discovered peptide with wide tissue distribution, regulates feeding behavior, improves glucose utilization, and inhibits insulin secretion. We examined whether apelin is expressed in human islets, as well as in normal and type 2 diabetic (T2D) animal islets. Further, we studied islet apelin regulation and the effect of apelin on insulin secretion. Apelin expression and regulatio
Aim. To study nurses' compliance to national guidelines (Sweden) for peripheral venous catheters and to establish the complication frequency connected to time in situ and bore size. Background. Worldwide, there are no standard peripheral venous catheters guidelines, and the need for elective replacement has been challenged. Furthermore, the time interval and need for elective change of peripheral
In this study, we first determined the low molecular weight dissolved organic carbon (LMW DOC) concentration-dependent kinetics of soil respiration in a temperate grassland soil sampled on successive occasions. We then used the established relationship to estimate in situ LMW DOC concentrations from basal respiration measurements. C-14-labelled glucose was used as a model substrate and was added t
Background: Epidemiological studies on the association between maternal exposure to persistent organic pollutants (POPs) and fetal growth alteration report inconsistent findings which weights in favor of additional studies. Methods: Blood samples were collected from interviewed pregnant women in Greenland (572), Kharkiv (611) and Warsaw (258) and were analyzed for CB-153 and p,p'-DDE by gas chroma
BACKGROUND: Associations between cadmium (Cd) and kidney function have been reported even at low levels of exposure in the general population. Recently, the causality of these associations has been questioned. OBJECTIVES: We examined associations between urinary Cd (U-Cd; a biomarker of exposure) and urinary proteins that are used as biomarkers of kidney effects, based on repeated short-term sampl
The studies in this thesis are based on questions raised in the clinical setting. Perioperative myocardial ischemia occurs more often than recognized. This may lead to myocardial infarction, increased morbidity, mortality, and health care costs. In the first study, myocardial metabolism was investigated before, during, and after 30 min of regional coronary artery occlusion, utilizing the microdi
Dagens TV-program bygger i de flesta fall på ett bakomliggande TV-format. Formaten har under de senaste åren blivit en allt viktigare del av TV-industrin och idag är de föremål för en handel som årligen omsätter miljardbelopp. I takt med att marknaden för format expanderat har ökande konkurrens inom mediebranschen gjort att striden om TV-tittarna hårdnat. TV-bolagen har tvingats fokusera allt mer The television programs of today are in most cases based on an underlying television format. The use of TV formats has in recent years become an increasingly important part of the television industry and today they are subject of a billion dollar trade. As a result of the format market's expansion and the increased competition within the media industry the battle for viewers has intensified. T
Populärvetenskaplig sammanfattning: Supernovor och andra galaktiska system skickar ut mängder av atomkärnor med nära ljusets hastighet, så kallad kosmisk strålning. Eftersom supernovor framförallt finns i spiralarmarna i vår galax och jorden över långa tidsperioder rör sig relativt spiralarmarna så har det föreslagits att kosmisk strålning inte varit konstant under jordens historia. Vidare har visIt has been suggested that the cosmic ray flux varies as Earth moves relative to the spiral arms in the galaxy. However, no satisfying record over the cosmic ray flux over long time scales has been presented. This work aims to investigate the possibility to use cosmic ray tracks in silicate mineral inclusions in sediment-dispersed extraterrestrial chromite (SEC) grains as such a record. Chromite i
Introduction: In recent years, the e-commerce industry has developed at extremely high speed all over the world and becomes the sunrise industry. Besides, there is a megatrend that customers are pursuing better experience along the whole shopping journey. Statistics show that good reverse logistics service is an efficient way to improve customers satisfaction level. Among the reverse logistics, th
By combining a legal doctrinal study and an empirical interview study, this thesis examines the implementation of the right to access to justice under article 13 of the Convention on the Rights of Persons with Disabilities for persons who due to post-traumatic stress syndrome have difficulties accounting for their stories in asylum proceedings. The starting point is that persons with PTSD likely w
This thesis addresses the correlation between creditor protection and thecross-border seat transfer of companies in the light of the case law of the European Court of Justice concerning the freedom of establishment of undertakings. After the restrictive outcome of Daily Mail, the judgment of the European Court of Justice in Centros took the legal community by surprise. The following cases of Übers
Då HovR över Skåne och Blekinge, mål nr. B 2802-10, avkunnade sin dom den 21 september 2011 hade ytterligare en frikännande misshandelsdom behandlats av det svenska rättssystemet. Den tilltalade hade piskat målsäganden med olika redskap så att skador uppkommit. Det som skiljde detta mål från ett vanligt misshandelsmål, var att målsäganden hade samtyckt till de olika handlingarna, som en del av ettAs the Court of Appeals for Skåne and Blekinge, case no. B 2802-10, gave its judgment on September 21, 2011, was yet another acquittal assault judgment processed by the Swedish judicial system. The accused had hit the victim with different instruments in a way that caused damage to the plaintiff. However, what distinguishes this case from an ordinary assaultcase was that the plaintiff had consente
Sandvik Rock Processing in Svedala is a business area within the Sandvik Group who manufactures crushers and spare parts. A new production plant, Greenfield, will be completed in 2013 and as part of the change the company makes in connection with the new plant, there is a desire to revise and optimize the order quantities in the production. There are several models for lot sizing. Economic Order Q
Sealings are an important part in the industrial robot. One important property of the seal is to keep all particles and fluids from the outside, away from the important components inside the robot. Another important property is to keep the oil and grease inside the robot, and prevent leakage. The seal also prevent leakage inside the industrial robot and reduces the risks of sensitive components to
Large carnivore conservation in the Swedish multi-use landscapes can only be successful if carnivores can share the landscape with human activities. Interventions to reduce the risk of brown bear, lynx, wolf, and wolverine attacks on domestic animals have become a core element in carnivore management. Whereas the intention is that interventions mitigate human-carnivore interactions, the interventi
Key points: Parts of the fields of neuroscience and neurology consider the neocortex to be a functionally parcelled structure. Viewed through such a conceptual filter, there are multiple clinical observations after localized stroke lesions that seem paradoxical. We tested the effect that localized stroke-like lesions have on neuronal information processing in a part of the neocortex that is distan
BACKGROUND: Although growing evidence suggests that early-life excess manganese (Mn) impairs neurodevelopment, data on the neurodevelopmental effects of mancozeb, a fungicide containing Mn, and its main metabolite ethylenethiourea (ETU) are limited. OBJECTIVE: We examined whether prenatal mancozeb exposure and excess Mn were associated with neurodevelopment in 355 1-y-old infants living near banan
