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We study a model of the atrioventricular node function during atrial fibrillation (AF), for which the model parameters can be estimated from the ECG. The proposed model is defined by parameters which characterize the arrival rate of atrial impulses, the probability of an impulse choosing either one of the two atrioventricular nodal pathways, the refractory periods of these pathways, and the prolon

Background: Drug therapy in primary care is a challenge for general practitioners (GPs) and the prescribing decision is influenced by several factors. GPs obtain drug information in different ways, from evidence-based sources, their own or others? experiences, or interactions with opinion makers, patients or colleagues. The need for objective drug information sources instead of drug industry-provi

A kinetic model describing the enzymatic saccharification of wheat starch by a mixture of ol-amylase and amyloglucosidase has been developed. The model describes the influence of pH, glucose inhibition and starch and enzyme concentration, The results of experimental saccharification under different physical conditions, eg pH and temperature, were used to determine the parameters in the model. The

Selective activation of the estrogen receptor (ER) could be a safe approach to hormone replacement therapy for both women and men, in contrast to the estrogens currently used for women which activate both ER and ER, occasionally causing severe side effects. cis-10-SR, was shown to have an EC50 value of <1nM, potency 100-fold higher than that of AC-131. Even more interestingly, compound trans-10-SS

Electrocardiograms are routinely obtained in clinical follow-up of patients with asymptomatic aortic stenosis (AS). The association with aortic valve, left ventricular (LV) response to long-term pressure load, and clinical covariates is unclear and the clinical value is thus uncertain. Data from clinical examination, electrocardiogram, and echocardiogram in 1,563 patients in the Simvastatin and Ez

We use formaldehyde (HCHO) vertical column measurements from the Scanning Imaging Absorption spectrometer for Atmospheric Chartography (SCIAMACHY) and Ozone Monitoring Instrument (OMI), and a nested-grid version of the GEOS-Chem chemistry transport model, to infer an ensemble of top-down isoprene emission estimates from tropical South America during 2006, using different model configurations and a

Sustainability is a concept that has generated a great political and scientific debate during the last two decades, especially from the moment it was added to the concept of development. This has led to the distinction of two main interpretations of the term: weak and strong sustainability. The basic difference between both is that the first considers natural, manufactured and human capitals are s

Meteor radar observations carried out in August-September 1953-84 at theOnsala Space Observatory in Sweden show long-term, as well as short termvariations in meteor radar rates. These rate variations are associatedwith position in the solar cycle, and with variations in the solar windsector structure. An inverse correlation is found between meteor radarrates and the solar cycle. The magnitude of t

Popular Abstract in Swedish Trastsångarnas MHC gener i klarspråk Inuti kroppen ser vi väldigt lika ut allihop; men om mina njurar skulle sluta att fungera är det inte alls säkert att just du kan donera en njure till mig. Detta beror på att våra transplantations-gener eller s.k. MHC- (Major Histocompatibility Complex) gener är olika, och vid en transplantation måste många av donatorns och mottagarIn vertebrates the Major Histocompatibility Complex (MHC) plays a central role in the specific immune defence against various pathogens. Compared with other coding genes the MHC genes exhibit an extremely high level of polymorphism that is maintained by balancing selection. The importance in the immune defence and the polymorphism make these genes interesting to study from an ecological and evolut

Using laser-Doppler flowmetry during ventriculocisternal perfusion with inulin-[14C]carboxylic acid, choroid plexus blood flow (CPBF) and CSF production were measured simultaneously in rats during periods of 3 h. Blood flow and CSF production decreased only slightly during control experiments. The effect of vasoactive intestinal polypeptide (VIP) was studied at different concentrations of the pept

The results of a search for direct pair production of the scalar partner to the top quark using an integrated luminosity of 20.1 fb(-1) of proton-proton collision data at = 8 TeV recorded with the ATLAS detector at the LHC are reported. The top squark is assumed to decay via or , where denotes the lightest neutralino (chargino) in supersymmetric models. The search targets a fully-hadronic final st

Vibrationally resolved valence-shell photoionization spectra of H(2), N(2) and CO have been measured in the photon energy range 20-300 eV using third-generation synchrotron radiation. Young's double-slit interferences lead to oscillations in the corresponding vibrational ratios, showing that the molecules behave as two-center electron-wave emitters and that the associated interferences leave their

BACKGROUND AND AIMS: Autoantibodies against the zinc transporter 8 (ZnT8A) are common in type 1 diabetes (T1D). ZnT8A analyses are complicated by the fact that there are three variants of the autoantigen at amino acid position 325 representing ZnT8-R (Arginine), ZnT8-W (Tryptophan) and ZnT8-Q (Glutamin). The aims of the study were: 1) to develop an autoantigen triple mix Radio-Binding Assay (RBA)