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The first attempt to apply electrochemotherapy (ECT) to the brain was reported in 1993 by Salford et al. 1993 (1). They managed to significantly prolong the survival of RG2 glioma bearing Fischer-344 rats by 200% by iv administration of bleomycin followed by intracranial electrochemotherapy with exponential decaying pulses. In collaboration with the department of tumor immunology, Lund University,
Under the principle of freedom of contract, when two parties begin contract negotiations, they are under no obligation to actually arrive at an agreement and each one carries the risk for its own expenses and losses caused by the negotiations. However, even if the main rule says that each party bears the costs it might have incurred during the negotiations, if the parties do not reach an agreement
The effects of hypothermia on hypoglycemic brain damage were studied in rats after a 30-min period of hypoglycemic coma, defined as cessation of spontaneous EEG activity. The rats were either normothermic (37 degrees C) or moderately hypothermic (33 degrees C). Morphological brain damage was evaluated after various periods of recovery. Hypothermic animals with halothane anesthesia never resumed sp
Planar lung scintigraphy is a standard method used for the diagnosis of lung embolism, but it is hampered by the high incidence of nondiagnostic tests. Ventilation/perfusion SPECT may possibly improve this situation. The objective of this study was to compare planar lung scintigraphy with ventilation/perfusion SPECT using pigs with artificially engendered lung emboli labeled with (201)Tl. METHODS:
We present a sample of 705 local giant stars observed using the New Mexico State University 1 m telescope with the Sloan Digital Sky Survey-III/Apache Point Observatory Galactic Evolution Experiment (APOGEE) spectrograph, for which we estimate stellar ages and the local star formation history (SFH). The high-resolution (R ̃ 22,500), near infrared (1.51-1.7 μm) APOGEE spectra provide measurements o
We aimed to evaluate the clinical utility of stationary tissue background phase correction for affecting precision in the measurement of Qp/Qs by cardiovascular magnetic resonance (CMR). We enrolled consecutive patients (n = 91) referred for CMR at 1.5T without suspicion of cardiac shunt, and patients (n = 10) with verified cardiac shunts in this retrospective study. All patients underwent phase c
In this work, the near-field and far-field electric magnetic (EM) wave distributions of metallic slits was observed using tapered fiber probe and modelled using finite difference time domain (FDTD) computer simulations. The EM wave field distribution from rectangular slits with widths 100 nm, 300 nm, and 500 nm was mapped with excitation wavelength λ = 532 nm. λ/2 can be considered a characteristi
PurposeThe purpose of this study is to understand current trends and challenges in omnichannel logistics.Based on the study findings, a number of propositions are formulated.Design/methodology/approachAn exploratorysurvey study is conducted with 28Swedish retail companies that are involved with or plan to engage in omnichannel logistics. The study investigates the retailers’ previous
This thesis contains six papers dealing with different aspects of damage and fracture in paper. The work addresses the problem of material length scales in the context of deformation and fracture of paper materials. In Paper 1, localised failure in low-basis weight paper is studied and a fracture model based on continuum damage mechanics is presented. A gradient enhanced theory is used that incorp
An experimental and theoretical study of compaction, flow and hydrodynamic dispersion in a chromatographic column containing non-rigid particles is presented. Experiments were performed using chromatographic columns packed with either a dextran-based chromatographic gel or glass beads. It was found that both the velocity variations and the dispersion irregularities in the column containing the co
Background: Discrimination of heart failure with preserved ejection fraction with pulmonary hypertension (HFpEF-PH) from pulmonary arterial hypertension (PAH) is crucial for clinical management but may be challenging due to similarities in clinical and comorbid characteristics. We aimed to investigate tumour and metabolism related proteins in differentiating HFpEF-PH from PAH. Methods: Sixty-nine
We utilize laser-induced breakdown spectroscopy for measuring mixture composition and temperature in flames. Spectroscopy of the plasma emission yields concentration information, while temperature is derived from the breakdown threshold pulse energy.
The pandemic put all underlying structural problems about the living conditions of older persons in Europe on display. The inadequate protection afforded to older persons during this crisis reflects the weak position of this group. Additionally, the growing ageing population in EU entails an urgent challenge to the union. In this chapter, I argue for what policies the EU needs to implement to ensu
BACKGROUND: Historically, a reduced serum sodium concentration has been used to diagnose absorption of electrolyte-free irrigating fluid during transurethral resection of the prostate (TURP). In bipolar TURP, the irrigating solution contains electrolytes, thus invalidating the serum sodium method. In this study, we investigated whether glucose can be used to diagnose the absorption of irrigating f
BackgroundThere is a need for a measure that can be used across countries and cultures to advance cross-cultural research about internalizing mental health symptoms in children and adolescents. The Revised Children's Anxiety and Depression Scale (RCADS) is a potential candidate, but no study has examined whether its scales are measured similarly in youth populations from different countries.Method
The aim of this study was to describe first-time mothers' views of satisfaction with their first encounter with the nurse, in order to investigate differences between home visits and clinic visits and between high/middle and low socioeconomic classification (SEC). A nation-wide postal questionnaire sent to 800 first-time mothers yielded the data for statistical analysis. Data were collected using
Background: 2D digital subtraction angiography (DSA) images are the gold standard for neuroradiological vascular assessment and the basis of interventional procedures such as mechanical thrombectomy and cerebral aneurysm coiling. However, length measurements in projected DSA images are affected by the distance between the x-ray source, the object, and the detector. Precise coordination between all
In many contexts of multilingualism, language learners can initiate communication in the target language (TL), or a contact language (such as English). Patterns of use emerging from these choices affect TL development. They also vary between individuals. Willingness to communicate (WTC) needs to be investigated in ways that capture these variations. So far, WTC has not been studied in multilingual
In many contexts of multilingualism, language learners can initiate communication in the target language (TL), or a contact language (such as English). Patterns of use emerging from these choices vary between individuals and affect TL development. Willingness to communicate (WTC) needs to be investigated in ways that capture these variations. So far, WTC has not been studied in multilingual contex
