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The effect of friction between the dowel and the surrounding timber was studied for single dowel-type joints. The joints tested were divided into two groups of joints, where the surface of the dowels differed. For the first group, the dowels had a smooth surface and for the second group the dowels had a rough surface. A contactfree measurement technique was used in the experimental investigatio
The paper introduces the philosophy and current status of a benchmark for the evaluation of control strategies in wastewater treatment plants and also the forthcoming developments and future perspectives. The work has been carried out within the framework of two COST Actions (682 and 624) and in close collaboration with the IWA Task Group on Respirometry. The benchmark is a platform-independent si
This experimental study examines the influence of moisture variations on the load-bearing capacity of steeltimber dowel joints. The glulam specimens used to manufacture the joints were first exposed to controlled climate changes. After being stored in the climate chambers, holes were drilled and dowels were inserted. Then, the joints were loaded to failure. The main aim of this study was to inv
The Euro50 is a proposed 50m extremely large telescope for optical and infrared wavelengths. To study and predict the performance of the complete telescope system, an integrated model combining the structural model of the telescope, optics models, the control systems and the adaptive optics has been established. Wind and atmospheric disturbances are also included in the model. The model is written
Objectives: To develop evidence-based recommendations for the diagnosis of hand osteoarthritis (OA). Methods: The multidisciplinary guideline development group, representing 15 European countries, generated 10 key propositions regarding diagnosis using a Delphi consensus approach. For each recommendation, research evidence was searched for systematically. Whenever possible, the sensitivity, specif
Understanding farmer behaviour is needed for local agricultural systems to produce food sustainably while facing multiple pressures. We synthesize existing literature to identify three fundamental questions that correspond to three distinct areas of knowledge necessary to understand farmer behaviour: 1) decision-making model; 2) cross-scale and cross-level pressures; and 3) temporal dynamics. We u
A general method is presented for patient-specific three-dimensional (3D) absorbed dose calculations based on quantitative SPECT activity measurements. The computational scheme includes a method for registration of the CT study to the SPECT image, and compensation for attenuation, scatter, and collimator-detector response including septal penetration, performed as part of an iterative reconstructi
We report complete mitochondrial (mt) genomes for a penguin (little blue, Eudyptula minor) and a goose (greater white-fronted, Anser albifrons). A revised annotation of avian and reptile mt genomes has been carried out, which improves consistency of labeling gene start and stop positions. In conjunction with this, a summary of mt gene features is presented and a number of conserved pattems and int
OBJECTIVE - This study investigated the effect of moderate exercise on the absorption of inhaled insulin via the AERx insulin diabetes management system (iDMS). RESEARCH DESIGN AND METHODS - in this randomized, open-label, four-period crossover, glucose clamp study 23 nonsmoking subjects with type I diabetes received a dose of 0.19 units/kg inhaled human insulin followed in random order by either
We serendipitously identified a single nucleotide polymorphism (SNP), 8636C > A (rs1804197) in the T-untranslated region of the adenomatous polyposis coli (APC) gene to be associated with autism spectrum disorder (ASD). In order to gain further evidence for the association between the APC locus and ASD, we genotyped four additional adjacent common SNPs (rs2229992, rs42427, rs459552, and rs465899)
In topology optimization, iterative, gradient-based methods are used to find the material distribution of structures which maximizes some objective function, typically the structures' stiffness, or in some cases the fundamental frequency. Finite element analysis is used to compute the structural response in each iteration, leading to large systems of equations. Several hundred iterations may b
The automated machining is typically performed by CNC (Computer Numerical Control) machinery due to the high stiffness and accuracy provided by these machines, which are expensive and comparably big. For softer materials, such as aluminum, machining is possible using the less stiff industrial robot arm. This is attractive because the robot arm has a much lower cost than CNC combined with a larger
Contest-based crowdsourcing is a popular method for companies to gather ideas or information in a creative way, and the contestants’ motivations to participate in such competitions are not the same. Different factors influence the willingness of contestants to participate in contests. Yet these motives are not applicable to all types of crowdsourcing. This paper investigates the motivations and fi
Migrating cells under various force fields in microfluidic devices has been used as a tool to study the cell properties. Cells respond to the same force field in different ways depending on their properties, resulting in different migration velocities and trajectories which are obtained by cell tracking. The cells that are to be tracked are typically labelled with fluorescent dyes to enhance the c
Planets that orbit their host star closely experience tidal forces due to the strength of gravity not being uniform all over the planet. This leads to effects such as tidal spin synchronization, tidal eccentricity damping and tidal semi-major axis damping. This project aims to study how the time scales for these phenomena are affected by the planetary parameters such as mass, radius and the tidal
Popular Abstract in Danish Genterapi er en attraktiv terapiform mod neurologiske lidelser som Parkinsons sygdom og epilepsi af flere grunde. Gener med en terapeutisk effekt kan introduceres lokalt ved præcise injektioner i det syge væv, hvor genproduktet kan frigives fra nerveceller i respons til aktivitet i det omgivende væv. Ved genterapi omgås den forhindring som blod-hjernebarrieren udgør, ligGene therapy is an attractive strategy for neurological disorders, such as Parkinson’s disease and epilepsy, for several reasons. Introduction of genes with a therapeutic potential can be achieved locally, by accurate injections in the compromised tissue, and release of a transgene therapeutic substance can be regulated by the surrounding host neural circuitry. The gene therapy approach circumvent
Context. The solution of the nonlocal thermodynamical equilibrium (non-LTE) radiative transfer equation usually relies on stationary iterative methods, which may falsely converge in some cases. Furthermore, these methods are often unable to handle large-scale systems, such as molecular spectra emerging from, for example, cool stellar atmospheres. Aims. Our objective is to develop a new method, whi
Den tilltalades tidigare brottslighet kan i svensk rätt påverka påföljdsbestämningen för ny brottslighet, dvs. straffmätning och påföljdsval, på främst tre sätt. I första hand kan den tidigare brottsligheten beaktas genom ett skärpt påföljdsval. I andra hand har rätten möjlighet att förklara villkorligt medgiven frihet förverkad. I sista hand finns det genom straffskärpning möjlighet att förlänga
