Filetype
Analyzing the progression of Alzheimer's disease (AD) is challenging due to lacking sensitivity in currently available measures. AD stages are typically defined based on cognitive cut-offs, but this results in heterogeneous patient groups. More accurate modeling of the continuous progression of the disease would enable more accurate patient prognosis. To address these issues, we propose a new mult
“Wet” eldercare facilities for people who age with long-term substance use problems and complex needs exist in several countries. Residents are accepted as active users of alcohol and drugs, and while the media has presented the permissive policies of the facilities in a positive light, others have described these policies as harmful. The aim of this article is to analyze residents' and staff memb
Background: We studied the association between cardiorenal function and survival, neurological outcome and trends in survival after in-hospital cardiac arrest (IHCA). Methods: We included cases aged ≥ 18 years in the Swedish Cardiopulmonary Resuscitation Registry during 2008 to 2020. The CKD-EPI equation was used to calculate estimated glomerular filtration rate (eGFR). A history of heart failure
Detecting the entire repertoire of tumor-specific reactive tumor-infiltrating lymphocytes (TILs) is essential for investigating their immunological functions in the tumor microenvironment. Current in vitro assays identifying tumor-specific functional activation measure the upregulation of surface molecules, de novo production of antitumor cytokines, or mobilization of cytotoxic granules following
Background The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) creatinine equation is routinely used to assess renal function but exhibits varying accuracy depending on patient characteristics and clinical presentation. The overall aim of the present study was to assess if and to what extent glomerular filtration rate (GFR) estimation based on creatinine can be improved.MethodsIn a cro
This study investigated the feasibility of targeting the free, unbound forms of prostate-specific antigen (fPSA) for in vivo imaging of prostate adenocarcinomas (PCa), as PSA is produced and secreted at abundance during every clinical stage and grade of PCa, including castration-resistant disease. We injected (125)I-labeled monoclonal antibody PSA30 (specific for an epitope uniquely accessible on
In the study presented in this paper, experimental data from a pneumatic hybrid has been compared to the results from a simulation of the engine in GT-Power. The engine in question is a single-cylinder Scania D12 diesel engine, which has been converted to work as a pneumatic hybrid. The base engine model, provided by Scania, is made in GT-Power and it is based on the same engine configuration as t
En bärande princip för klanderprocessen är att hovrätten inte får ägna sig åt någon materiell överprövning. I klanderprocesser prövas i huvudsak om det i skiljeförfarandet förekommit något processuellt fel. För prövningen gäller samma processuella regelverk som för tvistemål i underrätt. Ett av de processuella verktyg som kan användas i klanderprocesser är 42 kap. 5 § 1 st. andra meningen RB. Den One of the basic principles of the challenge process is that the Court of Ap-peals should not engage in any substantive review. In challenge proceedings, the focus is on whether there have been any procedural errors in the arbitration process. The same procedural rules that apply to civil litigation in lower courts are also applicable to these reviews. One of the procedural tools that can be used
Incest är ett brott som under många århundraden bytt både namn och krimi-naliseringsgrunder. Trots att det råder delade meningar huruvida brottet är relevant i dagens lagstiftning finns brottet i 6 kap. 7 § BrB. Brottet har fun-nits ända sedan medeltiden och redan i de tidigaste nedskrivna lagarna finns bestämmelser om incest. Uppsatsens syfte är att undersöka hur brottet incest sett ut i Sverige
When building below ground level in cities the regulations regarding deformations of surrounding soil are very strict. When using conventional methods of calculation it is difficult to predict the occurring deformations. This is why it has become more common to use FE-modeling to determine deformations. With FE-modelling it is possible to take the interactions between soil and construction into co
The objective of this paper is to find out whether economic circumstances can have an impact on the level of risk aversion using a sample of data from the Netherlands. The testing strategy is based on the DNB Household Survey, which is issued by CentERdata. Launched in 1993, this database contains panel data up until the year 2011. Using such data allows for the study of psychological as well as e
BDSM är ett samlingsbegrepp för de sexuella disciplinerna Bondage/Disciplin, Dominans/Submission och Sadomasochism. Syftet med denna uppsats är att utreda rättssäkerhetsbrister vid gränsdragningen mellan straffansvar och ansvarsfrihet vid våldsutövning i BDSM-relationer. De två nivåer som ska vara uppfyllda för att ett samtycke ska verka ansvarsbefriande enligt 24 kap. 7 § BrB är samtyckets giltigBDSM is an overlapping abbreviation of the sexual practices Bondage/Discipline, Dominance/Submission and Sadomasochism. The purpose of this thesis is to examine deficiencies in the rule of law regarding the boundary between criminal liability and discharge from liability in BDSM-relations. For consent to be a ground for exemption from criminal responsibility according to Chapter 24 Section 7 in th
Den 12 juni 2019 överlämnade en av regeringen utsedd särskild utredare sitt betänkande SOU 2019:32 och den 6 april 2021 la regeringen fram proposition 2020/21:170 med förslag om införandet av ett särskilt barnfridsbrott. Den föreslagna straffbestämmelsen omfattar gärningen att utsätta ett barn för att bevittna vissa utpekade brott i 3, 4, 6 och 12 kap. BrB när de begås mot en närstående. Denna uOn 12 June 2019, a special inquiry officer appointed by the Swedish government submitted the report SOU 2019:32, and on 6 April 2021, the government presented the Government Bill 2020/21:170 with a proposal for the introduction of a special penal provision on violation of a child’s integrity. The proposed penalty provision covers the act of exposing a child to witness certain designated offences i
Computational models play an increasingly vital role in scientific research by enabling the numerical simulation of complex processes. Such models are also fundamental in geosciences. For instance, they offer critical insights into the impacts of global change on the Earth system today and in the future. Beyond their value as research tools, models are also software products and should therefore a
This Master’s thesis was done in collaboration with ABB Force Measurement and the task was to develop a product design concept of an electronic unit, used as a controller in ABB Force Measurement’s product systems. As part of the result a guide to be used when working with industrial design questions was also made. ABB Force Measurement develops measurement products mostly used by the rolling mil
Background: Brevican, neurocan, tenascin-C, and tenascin-R are extracellular matrix (ECM) proteins that are mainly expressed in the brain. They play important roles in proliferation and migration of neurons and other cell types in the brain. These ECM proteins may also be involved in various pathologies, including reactive gliosis. Objective: The aim of the study was to investigate if ECM protein
Background: Traumatic peripheral nerve injury is common and incurs significant cost to individuals and society. Healing following direct nerve repair or repair with autograft is slow and can be incomplete. Several bioengineered nerve wraps or devices have become available as an alternative to direct repair or autologous nerve graft. Nerve wraps attempt to reduce axonal escape across a direct repai
