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G protein-coupled receptor 30 (GPR30), also named G protein-coupled estrogen receptor (GPER), and the β1-adrenergic receptor (β1AR) are G protein-coupled receptors (GPCR) that are implicated in breast cancer progression. Both receptors contain PSD-95/Discs-large/ZO-1 homology (PDZ) motifs in their C-terminal tails through which they interact in the plasma membrane with membrane-associated guanylat
BACKGROUND: Early glottic cancer can be treated with laser resection or radiotherapy. In an earlier study, we found that voice function after laser resection was inferior to that after radiotherapy.OBJECTIVES: This study was designed to determine if reduced margins at laser resection improved voice function without impairing oncologic results.METHOD: A total of 268 patients with previously untreat
We present a tool for modeling conflict situations that enables simulation and testing of situation awareness in shared autonomy, in this case in an autonomous driving scenario. The flexibility of the tool allows definition of new conflict situations, integration with various control and conflict detection systems, as well as customization of Takeover Request (TOR) signals and different means of c
This paper formalizes the use of integral and differential cumulants for measurements of multiparticle event-by-event transverse momentum fluctuations, rapidity fluctuations, as well as net-charge fluctuations. This enables the introduction of multiparticle balance functions, defined based on differential correlation functions (factorial cumulants), that suppress two- and three-prong resonance dec
This paper develops an hourly forward curve for power markets where the intra-day and intra-week shapes (profiles) depend on the level of the hydrological balance. The shaping model is based on a feed-forward Artificial Neural Network (ANN), which is trained on a historical data set of hourly electricity spot prices from the Nord Pool market and weekly measurements of the Nordic hydrological balan
The dual control problem for time-varying or non-linear systems is inherently analytically and computationally untractable due to the demand of alternating minimizations and mean value computations. Hence, it has to be approached using approximations leading to suboptimal dual control. The core of the successful approximative controller is its ability to be able to consider future changes in the d
Multi-sample anti-aliasing is a popular technique for reducing geometric aliasing (jagged edges) and is supported in all modern graphics processors. With multi-sampling anti-aliasing, visibility and depth are sampled more than once per pixel, while shading is done only once per pixel per primitive. Although this significantly reduces the appearance of jagged edges around object boundaries, the ima
In this report we show that phage displayed antibodies can be selected based on dissociation rate constants, using a BIAcore(TM) biosensor. To demonstrate the principle, two Fab phage stocks displaying antibodies specific for hen egg lysozyme or phenyloxazolone were mixed in a ratio of 1:10 and injected over the biosensor chip containing immobilized lysozyme. Antigen-specific bound phages were elu
A mechanochemical method (grinding the components without added water - dry grinding, followed by further grinding in the presence of minute amount of water or NaOH solution - wet grinding) was used in this work for the preparation and intercalation of CaFe-layered double hydroxides (LDHs). Both the pristine LDHs and the amino acid anion (cystinate and tyrosinate) intercalated varieties were prepa
Background Breathlessness and fatigue are common symptoms in older people. We aimed to evaluate how different breathlessness dimensions (overall intensity, unpleasantness, sensory descriptors, emotional responses) were associated with fatigue in elderly men. Methods This was a cross-sectional analysis of the population-based VAScular disease and Chronic Obstructive Lung Disease (VASCOL) study of 7
Collective collapse occurs when a majority of the players in a team suddenly perform below expected level in a match, in spite of a satisfactory start, or when a team underperforms right from the start. Research results from a study on 146 male players and 15 coaches in various team sports at the elite level, and a study on a team involved in a collective collapse, and the opposite, a winning turn
Popular Abstract in Swedish Avhandlingen behandlar robotteknik och de nya möjligheter som den kan ge människor med rörelsehinder. Jag fokuserar på teknikanvändaren och teknikanvändningen, speciellt på vad som gör robothjälpmedel värda att använda. Distinktion görs mellan användvärdhet och användbarhet. Erfarenheter från användning av den rullstolsmonterade robotarmen Manus visar att tekniska krav
There are many benefits offered by integrated enterprise computer systems. There are a growing number of options available to obtain such management information system support. A major problem when selecting Enterprise Information Systems, in special ERP systems, is how to deal with the great diversity of options as well as the number of criteria used to evaluate each alternative. There is an impl
