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We propose a semianalytical formalism based on a time-domain resonant-mode-expansion theory to analyze the ultrafast temporal dynamics of optical nanoresonators. We compare the theoretical predictions with numerical data obtained with the FDTD method, which is commonly used to analyze experiments in the field. The comparison reveals that the present formalism (i) provides deeper physical insight o
The Biopython Project is a long-running distributed collaborative effort, supported by the Open Bioinformatics Foundation, which develops a freely available Python library for biological computation [1]. We present here details of the Biopython releases since BOSC 2016, namely Biopython 1.68, 1.69 and 1.70. Together these had 82 named contributors including 51 newcomers which reflects our policy o
Rare inherited bleeding disorders (IBD) are a common cause of bleeding tendency. To ensure a correct diagnosis, specialized laboratory analyses are necessary. This study reports the results of an upfront diagnostic strategy using targeted whole exome sequencing. In total, 156 patients with a significant bleeding assessment tool score participated in the study, of which a third had thrombocytopenia
Biochemical signaling is mediated by complexes between macromolecular receptors and their ligands, with the duration of the signal being directly related to the lifetime of the ligand-receptor complex. In the field of drug design, the recognition that drug efficacy in vivo depends on the lifetime of the drug-protein complex has spawned the concept of designing drugs with particular binding kinetic
Purpose: This paper aims to investigate the role that Italian third sector organizations have in the process of social and administrative categorization of newly arrived migrants living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/Aids) or hepatitis b. In Italy, free access to health is provided to all migrants and residence permits for medical treatment is granted for
The main objective of this paper is to demonstrate how greenhouse gas (GHG) emissions can be quantified during the evaluation of control strategies in wastewater treatment plants (WWTP). A modified version of the IWA Benchmark Simulation Model No 2 (BSM2G) is hereby used as a simulation case study. Thus, the traditional effluent quality index (EQI), operational cost index (OCI) and time in violati
OBJECTIVES: Lysosomal acid lipase (LAL) is the key enzyme, which degrades neutral lipids at an acidic pH in lysosomes. The role of LAL in various cellular processes has mostly been studied in LAL-knockout mice, which share phenotypical characteristics with humans suffering from LAL deficiency. In vitro, the cell-specific functions of LAL have been commonly investigated by using the LAL inhibitors
High-sensitivity cardiac troponin assays have become the gold standard for diagnosing acute and chronic myocardial injury. The detection of troponin levels beyond the 99th percentile is included in the fourth universal definition of myocardial infarction, specifically recommending the use of sex-specific thresholds. Measurable concentrations below the proposed diagnostic thresholds have been shown
Spectral imaging allows for the simultaneous visualization of multiple different spectral bands of a scene, and is a powerful tool used in a range of contexts - from the color cameras in smart phones, to scientific imaging applications such as remote sensing and fluorescence microscopy. The progress within these fields of research is therefore intrinsically linked to the advances made for more eff
This contribution discusses relations between the Swedish SAC and the legislature (Riksdag), focusing on how Sweden balances popular sovereignty with judicial independence. The analysis focuses on the legislature's influence on the SAC and – on the other hand – the SAC and its judges’ impact on the legislature, especially the constitutional control of draft legislation carried out by the Council oThis contribution discusses relations between the Swedish SAC and the legislature (Riksdag), focusing on how Sweden balances popular sovereignty with judicial independence. The analysis focuses on the legislature's influence on the SAC and – on the other hand – the SAC and its judges’ impact on the legislature, especially the constitutional control of draft legislation carried out by the Council o
Vertebrates capable of powered flight rely on wings, muscles that drive their flapping and sensory inputs to the brain allowing for control of the motor output. In birds, the wings are formed of arrangements of adjacent flight feathers (remiges), whereas the wings of bats consist of double-layered skin membrane stretched out between the forelimb skeleton, body and legs. Bird feathers become worn f
Traditional power reduction techniques such as DVFS or RAPL are challenging to use with web services because they significantly affect the services' latency and throughput. Previous work suggested the use of controllers based on control theory or machine learning to reduce performance degradation under constrained power. However, generating these controllers is challenging as every web service app
When we develop general-purpose robot software components, we rarely know the full context that they will execute in. This limits our ability to make predictions, including our ability to detect program bugs early. Since running a robot is an expensive task, finding errors at runtime can prolong the debugging loop or even cause safety hazards. In this paper, we propose an approach to help develope
Human communication is by default polysemiotic: it involves the spontaneous combination of two or more semiotic systems, the most important ones being language, gesture, and depiction. We formulate an original cognitive-semiotic framework for the analysis of polysemiosis, contrasting this with more familiar systems based on the ambiguous term "multimodality."To be fully explicit, we developed a co
This study investigated the longitudinal impact of methods for the drying off of cows with and without dry cow therapy (DCT) on the microbiota and resistome profile in colostrum and milk samples from cows. Three groups of healthy dairy cows (n = 24) with different antibiotic treatments during DCT were studied. Colostrum and milk samples from Month 0 (M0), 2 (M2), 4 (M4) and 6 (M6) were analysed us
An engineering model for estimating hot gas layer height is presented. The model is based on several sub-models, thus necessitating benchmarking against experimental data. Results from the model are compared to data from three different series of enclosure fire tests. The results indicate a strong correlation between the proposed model and the experimental observations, with an average error of le
Aims Many studies indicated use of diabetes medications can influence the electrocardiogram (ECG), which remains the simplest and fastest tool for assessing cardiac functions. However, few studies have explored the role of genetic factors in determining the relationship between the use of diabetes medications and ECG trace characteristics (ETC). Methods Genome-wide association studies (GWAS) were
This paper presents an investigation concerning the introduction of Extreme Programming (XP) in software development organisations. More specifically the concept of using a decision support method known as the Analytical Hierarchy Process (AHP) is evaluated by a group of students and a group of developers and the outcome is compared to experiences from an XP case study. The results provide an indi
Author: Ulrika Möllerström Title: Corporate Social Responsibility – the construction of its social dimension. Supervisor: Lars Harrysson Assessor: Carina Tigervall This paper has looked into how the social dimension of the concept “corporate social responsibility” (CSR) is constructed in corporate codes of conduct (CoC) from Swedish clothing companies. Previously made research have shown that no
