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BACKGROUND: Collagen-induced arthritis (CIA) is the most commonly used model of rheumatoid arthritis (RA). In both CIA and RA there is an increase in the cellular content of the synovium, this being dominated by macrophages. OBJECTIVE: To assess the impact of etoposide, a topoisomerase II antagonist known to induce monocyte apoptosis, on the development of CIA. METHODS: Mice were primed and booste

Popular Abstract in Swedish Sophia Elisabeth Brenner (1659-1730) var Sveriges första stora kvinnliga poet. Hon var verksam som författare och lärd kvinna under femtio år, och var dessutom en flitig brevskrivare. Avhandlingen baseras på en inventering av bevarade brev till och från Sophia Brenner skrivna på latin, svenska, franska och italienska. Hennes nylatinska korrespondens med danske Otto SpeSophia Elisabeth Brenner (1659-1730) was Sweden's first great female poet, writing and publishing her poems over a period of fifty years. She was also, however, a prolific letter writer. The dissertation is based on an inventory of all the preserved letters to and from her written in Latin, Swedish, French and Italian. Her Neo-Latin correspondence with the Dane Otto Sperling the Younger is presen

Deficiency of complement components within the classical pathway is associated with increased risk for immune complex disease. However, C2-deficient individuals often have a mild disease and about 50% are healthy. To study the importance of the different components for immune complex clearance, bovine serum albumin (BSA)/anti-BSA complexes were opsonized in human serum and the binding to erythrocy

Popular Abstract in Swedish Förbränningsmotor är i dagens värld den mest använda kraftkällan för fordon. Förbränningsmotorn har kontinuerligt utvecklats och förbättrats sedan Nicolaus August Ottos och Rudolf Diesels dagar, och kommer att fortsätta att utvecklas långt in i framtiden. Ingen konkurrerande teknik har ännu på allvar utmanat förbränningsmotorns ställning. Det finns en lång rad tänkbara The prime mover in the world today is the Internal Combustion (IC) engine. The development and improvement of the internal combustion engines since Nicolaus August Otto and Rudolf Diesel has continued until today and will continue long into the future. No major competitor to the IC engine has yet emerged. There is a long list of potential competitors but they still have to prove their superiority

Recently, common noncoding variants in the TCF7L2 gene were strongly associated with increased risk of type 2 diabetes in samples from Iceland, Denmark, and the U.S. We genotyped 13 single nucleotide polymorphisms (SNPs) across TCF7L2 in 8,310 individuals in family-based and case-control designs from Scandinavia, Poland, and the U.S. We convincingly confirmed the previous association of TCF7L2 SNP

The aim of the study was to establish the influence of dexamethasone and alpha-ketoglutarate administration to pregnant sows on the prenatal programming of the growth hormone level, cortisol, insulin and IGF-I in the blood serum of newborn piglets assessed just after their birth and prior to suckling. The foetal development is dependent on and determined by hormones such as glucocorticoids as well

The HFB cranked shell model is applied in an investigation of the selfconsistent pairing properties of the superdeformed (SD) bands in Eu-143. Results from a fully pairing and deformation selfconsistent mesh calculation of the properties of the most intense SD band in 143Eu are presented, as well as pairing selfconsistent calculations done at a fixed deformation close to the SD minimum for an exci

To demonstrate the psychological importance of social changes in behavioural practice, three interview studies were carried out in Sweden, each in the decade of 1970, 1980 and 1990. All subjects were university students, as were te subjects in a study performed 1959 which served as an "anchor study". The results were analysed using the following three perspectives:(1)Hegemonic social appeals rega

BACKGROUND AND PURPOSE: The purpose of this study was to evaluate whether grafting of fetal neocortical tissue 1 week after focal brain ischemia improved behavioral outcome and reduced secondary thalamic atrophy. METHODS: One week after distal ligation of the right middle cerebral artery in spontaneously hypertensive male rats, blocks of fetal neocortex (embryonic day 17) were homografted to rats

In this thesis we look at data where sedated patients have been pinpricked with a needle during an Auditory Brainstem Response recording. By looking at this data set with different statistical methods some butterfly pattern emerged and peaks appeared in the spectrum around the time where the needle pinpricking should have occurred. With this results a model was developed and evaluated. Future inve

This thesis conducts a cultural analysis of the social implications of food allergies and intolerances and analyzes the interaction of individual experience and social structures by asking what it means when one chooses not to follow the normative food culture, such as with vegetarian and vegan diets, or when one physically cannot, such as in the case of food allergies and intolerances, specifical

I uppsatsen analyseras Harry Potter-böckernas skildring av hur det dras upp gränser mellan olika raser inom magivärlden i förhållande till Zygmunt Baumans teori om hur judarna under 1800-talet utsattes för antisemitism på grund av att de antogs överskrida nationalitetsgränserna. Dessutom förs en argumentation för att böckerna kan läsas som en allegori över vår världs rasism. Rasismen i magivärlden

Thesis purpose: The purpose of the master thesis is to examine what affects Generation Y’s values, attitudes and beliefs towards the fair trade label and ecological quality labels. The purpose is also to investigate how these two quality labels are received by Generation Y, in order to delve deeper into the relationship between the labels. This research will contribute with new insights about Gene

The wax on the stem and leafs of the barley (Hordeum vulgare L.) plant has a protective function and is produced by the cells on the plant's outer surfaces. There are several available barley mutants where the wax production has been stopped. Four mutants are the single-site mutants cer-c.36, cer-q.42, ceru. 21 and the deletion mutant cer-cqu.724. We phenotyped 636 barley plants and collected

One reason why persons today wants to make their energy consumption more effective is that the energy price has increased and will probably increase even more. Another reason is that they worry about the carbon dioxide emission effects on the environment. These two motives together with the “Programme for improving energy efficiency”, PFE, initiated by the Swedish Energy Agency gave a platform for

Popular Abstract in Swedish Ökat antal patienter som lider av kärlsjukdomar behandlas idag med interventionella metoder istället för kirurgi. Dessa metoder populärt kallade ballong sprängningar, kombineras numera oftast med inläggande av ett metallnät (stent) som hjälper till med att förstärka kärlväggen, så den inte skall falla ihop efter ballong vidgningen. Oavsett vilken metod som används, kompBackground: Restenosis is the most frequently occurring adverse event after percutaneous intravascular treatment of atherosclerotic lesions, which limits long-term patency of the intervention. Objective: The aim of the study was to evaluate if minimizing vascular injury during treatment by insertion of self-expanding stents or modifying the reparative mechanisms by local drug delivery can reduce r

A regulation on nutrition and health claims made on foods was introduced in the European Union in 2007. This Regulation provides opportunities for the use of health claims on foods in Europe, including reduction of disease risk claims. The Regulation will be fully implemented by January 2010. A community list of permitted and rejected claims will be established and made available to the public. So