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Hippocampal extracellular levels of noradrenaline (NA), 5-hydroxytryptamine (5-HT), and 5-hydroxyindoleacetic acid (5-HIAA) were monitored with the microdialysis technique in freely moving rats. In one experiment 30 min samples were collected during 24 h of continuous perfusion, and the monoamine output was compared to the behavioural activity state, as arbitrarily classified in three categories:
Popular Abstract in Swedish Ökad förståelse för hjärtats pumpfunktion är av stort intresse för att kunna förbättra diagnostik, behandling och prognoser för hjärtsjuka patienter. Blodflöde i hjärtat är direkt kopplat till hjärtats form och rörelse och kan därför vara en viktig markör för hjärtats funktion. Därför var målet med denna avhandling att utveckla och förbättra mätningar av blodflöde med hIncreased understanding of the pumping mechanics of the heart are of great importance to develop diagnostics, treatment and prognostics for cardiovascular diseases. Blood flow in the heart is connected to its anatomy and function, and may therefore be a sensitive marker of cardiac health and disease. Therefore, the aim of this thesis is to develop and validate methods for quantification and visual
Seasonal water level fluctuations in rivers significantly influenced the cross-media migration, transformation, and risk diffusion of antibiotics from the vadose zone into groundwater. This study developed a coupled model integrating machine learning (ML) with HYDRUS-3D and GMS to accurately predict sulfamethazine migration under dynamic water levels. The predictive accuracy (E≥0.98) of this ML-HY
Robotised welding is one of the most important robot tasks used in manufacturing industry. The operator usually performs the programming of the robot manually, i.e. by jogging the robot arm to each coordinate pose in space. Programming can, however, be made more accurate by the use of simulation, using so called Computer Aided Robotics. Simulation can also be a powerful tool to evaluate and contro
Genomic manipulation of Yersinia ruckeri, a pathogen of salmonid fish species, is essential for understanding bacterial physiology and virulence. Here, we present a protocol for genomic recombineering in Y. ruckeri, a species reluctant to standard genomic engineering, using CRISPR Cas12a coupled with the λ Red system. We describe steps for identifying protospacer guides, preparing repair template
Introduction: Contact allergy to nickel (Ni) is a delayed-type hypersensitivity reaction mediated by Ni-reactive T cells producing the hallmark cytokines of several T-helper cell (Th) populations including IFN-γ(Th1), IL-4, IL-5 and IL-13 (Th2), and IL-17A (Th17). IL-22-expressing CD4+ cells, which could be either Th17 co-expressing IL-22 or Th22, expressing IL-22 in the absence of IL-17A, have al
Den boreala regionen innehåller 40% av jordens kol (C) som lagras i vegetation och mark med sina skogar som står för nästan 30% av den terrestra C sänkan. Boreala skogar upplever några av de snabbaste hastigheterna för klimatuppvärmning och ökningar i brandaktivitet, vilket hotar att släppa ut stora mängder av deras C reserver till atmosfären. Även om klimat och skogsbränder har stark kontroll öveThe boreal region contains 40% of the earth’s carbon (C) that is stored in vegetation and soils with its forests accounting for almost 30% of the terrestrial C sink. Boreal forests are experiencing some of the most rapid rates of climatic warming and increases in fire activity, threatening to release large amounts of their dense C reserves to the atmosphere. While climate and wildfire place strong
Background: Over the past decade, the use of organophosphate insecticides including chlorpyrifos has faced increasing restrictions due to health concerns, leading to a rise in use of pyrethroids. Concerns about neurodevelopmental insults following pyrethroids exposure exist, but few studies have examined the long-term effects of childhood exposure to chlorpyrifos and pyrethroids on IQ. Objective:
Cement är ett viktigt byggmaterial inom anläggnings- och geoteknik. Men dess tillämpningar för stabilisering av marina sediment behöver ytterligare undersökas. Denna artikel undersöker effekterna av olika mängder portlandcement tillsatt till sedimentprover vid urlakning av tributyltenn (TBT) från det förorenade marina sedimenterar och utvärderar pH-nivån. Identifiera de bästa kombinationerna av Po
Today the Unified Glare Rating (UGR) tabular method according to CIE 117-195 and CIE 190-210 is practically the only one used for evaluation of discomfort glare in the lighting design process but it is unknown if the method is in line with the subjective perception of glare (SGI). We investigated whether UGR calculation method currently used in lighting design is in agreement with the perceived di
Background: Systematic analyses of global health trends can provide an accurate narrative of progress and challenges. We analysed the impact of changing age-specific mortality (epidemiology) and age structure (demography) on crude death rates (CDRs) and causes of death with large or rising mortality to inform the third Lancet Commission on Investing in Health. Methods: Data from the World Populati
In this written study, I have researched video game music from the 90’s and early 2000’s to see what I can learn from the process of composing music for video games, as well as how the hardware and software capabilities of the game consoles shaped the music. First it presents my own background and relation to the subject, next it establishes what functionally separates video game music from conven
Syftet med denna uppsats är att analysera de juridiska möjligheter som finns för en borgenär att återfå en felaktig betalning som gjorts till ett konkursbo. I uppsatsen analyseras hur konkursrätten och avtalsrätten samverkar för att lösa dessa frågor. Uppsatsen utgår från ett specifikt fall där en borgenär, som av misstag betalat en skuld till ett konkursbo istället för att använda kvittningsrätteThe purpose of this thesis is to analyze the legal avenues available for a creditor to reclaim an erroneous payment made to a bankruptcy estate, focusing on how Swedish bankruptcy law and contract law intersect to address these issues. The thesis is based on a specific case in which a creditor mistakenly paid a debt to a bankruptcy estate instead of exercising the right of set-off and later attemp
With the wide-ranging crisis in Venezuela exacerbating since 2014 and Chile consolidating its leading economic position within Latin America, the number of Venezuelan immigrants in Chile has significantly grown. This paper aims to understand the push and pull factors of Venezuelans migrating to Chile and their perceived integration. The broader purpose is to better understand the push and pull fac
Den här uppsatsen ”Migrantkvinnor, Deras Rättigheter Där och Här: en kvalitativ intervjustudie om uppfattningen av migrantkvinnors tillgång till rättigheter, i ursprungslandet och i Sverige”, baseras på fyra intervjuer, två med individuell migrantkvinnor och två kvinnliga representanter för Svenska kvinnoorganisationer. Syftet med uppsatsen är att; förstå hur de intervjuade kvinnorna uppfattar migThis thesis is based on four interviews, two with individual migrant women and two with female representatives of Swedish women organisations. The purpose of the study is to; understand how the interviewed women perceive migrant women’s access to rights in Sweden and at their country of origin, with the help of Martha C. Nussbaum’s theory on central capabilities. The questions articulated in the q
High-elevation hydropower units in California might be sensitive to climate warming since they have been designed to take advantage of snowmelt and have low built-in storage capacities. Snowmelt is expected to shift to earlier in the year and the system might not be able to store sufficient water for release in high-electricity-demanding periods. Previous studies have tried to explore the climate
In recent years, it has been reported that sex education in Swedish schools has been lacking, and, thus, in 2022, new guidelines for sex education were implemented (sexuality consent and relationships, SCaR). This change meant that sex education is part of all curricula and that the responsibility to teach it rests on teachers of all subjects. With the theory of language as reproducing and changin
In the search for grasping how the everyday life experience for people with a disability is shaped in relation to the local social and political complexities in Cobija/Pando four themes are crucial to understand. Firstly, illustrating how the rhetorical definition of disability removes the wrongfulness or responsibility from the shoulders of the individual to an exclusive social environment. Even
