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Popular Abstract in Swedish Stora mängder reaktiva lågmolekylära ämnen används i den kemiska industrin vid produktionen av varor som hanteras i vårt dagliga liv. Exempel på sådana kemikalier är organiska syraanhydrider (OAA). En stor andel av de arbetare som exponeras för dessa viktiga industriella föreningar blir tyvärr sjuka med symtom som astma och hösnuveliknande besvär. I åtminstone en del faOrganic acid anhydrides (OAAs) are important industrial chemicals but also potent inducers of airways diseases. Many exposed workers develop specific IgE and IgG antibodies. Hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA) are two particularly sensitising OAAs. The aim of this thesis was to develop and evaluate a method for biological monitoring of exposure to and r

Autoantibodies against 21-hydroxylase (P450c21) are common in idiopathic autoimmune Addison’s disease. In the present work, we have developed a sensitive radiobinding assay using in vitro translated recombinant human 35S-P450c21. Levels of P450c21 antibodies (P450c21-Ab) were expressed as a relative index (P450c21 index) using a P450c21-Ab positive Addisonian serum and two antibody-negative health

BACKGROUND: Antibacterial peptidyl derivative - Cystapep 1, was previously found to be active both against antibiotic-resistant staphylococci and streptococci as well as antibiotic-susceptible strains of these species. Therefore, it is a promising lead compound to search for new antimicrobial peptidomimetics.OBJECTIVES: We focused on identifying structural elements that are responsible for the bio

PurposeTo ultimately make accurate and precise fetal noninvasive oxygen saturation (sO2) measurements by T2-prepared bSSFP more widely available by systematically assessing error sources in order to potentially reduce perinatal mortality in cardiovascular malformations and fetal growth restriction.MethodsT2-prepared bSSFP data were acquired in phantoms; in flowing blood in adults in the superior s

Structural Health Monitoring (SHM) can provide valuable information for maintenance-related activities and post-disaster emergency management. However, as with any technological system, SHM systems can be susceptible to errors due to malfunctioning. Therefore, it is essential to assess the potential for malfunctions and the associated costs of maintenance and repair when evaluating the long-term b

Summary: Upstream open reading frames (uORFs, often encoding so-called leader peptides) can regulate translation and transcription of downstream main ORFs (mORFs) in prokaryotes and eukaryotes. However, annotation of novel functional uORFs is challenging due to their short size of usually <100 codons. While transcription- and translation-level next-generation sequencing methods can be used for gen

We investigate the tetragonal phase of the binary transition metal oxide CuO (t-CuO) within the context of cellular dynamical mean-field theory. Due to its strong antiferromagnetic correlations and simple structure, analysing the physics of t-CuO is of high interest as it may pave the way towards a more complete understanding of high-temperature superconductivity in hole-doped antiferromagnets. In

Resveratrol is a photosensitive, bioactive molecule which has received increasing research interest during the past decade for its antioxidant properties. However, it has low solubility in water or common triglyceride oils. Resveratrol solubilization in oil can only be achieved in essential oils, such as flavour oils, but the stability of emulsions produced with this type of oils is low as they ar

Climate warming is currently advancing spring leaf-out of temperate and boreal trees, enhancing net primary productivity (NPP) of forests. However, it remains unclear whether this trend will continue, preventing for accurate projections of ecosystem functioning and climate feedbacks. Several ecophysiological mechanisms have been proposed to regulate the timing of leaf emergence in response to chan

User-related assessment of a level 3 automated driving system, providing functions such as lane- and distance-keeping, stop & go driving, lane change and overtaking, was carried out on a motorway in Germany with the aim to assess user-related issues of automated driving, i.e., behavior when driving with automation on motorways, user experiences, reactions and acceptance. Twenty-one persons dro

Miniaturized thermal infrared (TIR) cameras that measure surface temperature are increasingly available for use with unmanned aerial vehicles (UAVs). However, deriving accurate temperature data from these cameras is non-trivialsince they are highly sensitive to changes in their internal temperature and low-cost models are often not radiometrically calibrated. We present the results of laboratory a

Purpose: An unprecedented scale of human migration has lead humanitarians to view camps as long-term settlements rather than temporary holding facilities. The purpose of this paper is to increase the understanding of and identify challenges with this proposed new approach to camp design. Design/methodology/approach: Based on the camp design literature, the authors developed an interview guide and

All echolocating bats and whales measured to date emit a directional bio-sonar beam that affords them a number of advantages over an omni-directional beam, i.e. reduced clutter, increased source level and inherent directional information. In this study, we investigated the importance of directional sound emission for navigation through echolocation by measuring the sonar beam of brown long-eared b

Medication packaging is essential to provide patients with guidance and correct use of their medicines for effective treatment. This research aims to increase knowledge about the medication packaging innovation process and its uptake towards patient‐centered packaging design. The study applied a qualitative research approach based on data from 25 in‐depth interviews with stakeholders involved in m

Research infrastructures play a key role in launching a new generation of integrated long-Term, geographically distributed observation programmes designed to monitor climate change, better understand its impacts on global ecosystems, and evaluate possible mitigation and adaptation strategies. The pan-European Integrated Carbon Observation System combines carbon and greenhouse gas (GHG; CO2, CH4, N

This study looks at the effect international mining corporations have on local economic activity around gold mines in Burkina Faso. It also asks whether the mines have any additional effects, such as changes in poverty or inequality. The study does this by using remote sensing data, particularly nighttime lights, NDVI, and forest loss data to analyze the mine’s effect on the surrounding area. In a

När Tycho Brahe på 1500-talet stod i sin Stjärneborg på ön Ven utanför Landskrona och kartlagde stjärnhimlens rörelser utövade han vad vi i dag kallar för astrometri: att mäta himlakropparnas positioner och rörelser. I ett historiskt skede skulle precisionen i Tychos mätningar komma att knyta ihop astronomin med fysik för första gången. Johannes Kepler, Tychos medhjälpare och efterträdare, kunde mThe all-sky survey of Gaia will generate vast amounts of astrometric data, in which there are expected to be thousands of planets found. Finding a system of $n_\textup{p}$ planets requires fitting of a total $5+7n_\textup{p}$ parameters: five astrometric and seven Keplerian parameters for every planet. The problem is thus highly non-linear and computationally prohibitive. After exploiting the line

Skolan har ingen lång tradition av att arbeta laborativt i matematik och dynamisk programvara är ett sätt att fylla denna brist. Dynamisk programvara låter eleven gå i dialog, utmanar, skapar nyfikenhet, åskådliggör begrepp och underlättar inlärningen. Det krävs emellertid att lärare är villiga att sätta sig in i de relativt nya möjligheterna eftersom datoranvändning i matematik- och fysikundervisReportedly in Swedish schools, there is no long tradition of investigative and laboratory work in the mathematics subject. Dynamic software is a term which encapsulates the purpose of software as a pedagogical instrument in teaching. There is great potential in this but also a need for teachers to engage and apply themselves to the new possibilities. Computer software in class does not automatical

One component in writing development is a more efficient use of syntactic tools. Later syntactic development, specifically that of the noun phrase, is an understudied area, notably so for Swedish. The demand for specified and concise information in an expository text, and the availability of more planning time in the written modality, are important factors contributing to more complex noun phrases