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Substantial evidence now supports the hypothesis that the common ancestor of bats was nocturnal and capable of both powered flight and laryngeal echolocation. This scenario entails a parallel sensory and biomechanical transition from a nonvolant, vision-reliant mammal to one capable of sonar and flight. Here we consider anatomical constraints and opportunities that led to a sonar rather than visio
The particles in exhaled breath provide a promising matrix for the monitoring of pathological processes in the airways, and also allow exposure to exogenous compounds to be to assessed. The collection is easy to perform and is non-invasive. The aim of the present study is to assess if an exogenous compound - methadone - is distributed in the lining fluid of small airways, and to compare two method
The ISO22400 standard defines key performance indicators for manufacturing operation management. Its visionary goal is to be applicable to all industry types, regardless the production methodology and the process configuration. Pursuing this objective, a challenging trade-off between generality and specificity in the definitions must be found. In the cited standard, the former approach has been pr
Previous research has shown a male bias in the media. This study tests this statement by examining how the pronouns She and He are used in a news media context. More specifically, the study tests whether He occurs more often and in more positive semantic contexts than She, as well as whether She is associated with more stereotypically and essential labels than He is. Latent semantic analysis (LSA)
Popular Abstract in Swedish Beräkningsmässigt skalar många av de klassiska metoderna inom spatiell statistik kubiskt med antalet observationer, vilket är opraktiskt om datamängderna är stora. I de traditionella tillämpningarna av statistik på spatiella datamänger begränsades ofta antalet observationer på grund av höga mätkostnader och metodernas beräkningskomplexitet inte sällan ett problem. NumerThe focus of this work is on the development of new random field models and methods suitable for the analysis of large environmental data sets. A large part is devoted to a number of extensions to the newly proposed Stochastic Partial Differential Equation (SPDE) approach for representing Gaussian fields using Gaussian Markov Random Fields (GMRFs). The method is based on that Gaussian Matérn fie
Residual masses are frequently found in patients with aggressive lymphomas, following therapy. A study was undertaken to determine whether initial tumour size, changes during treatment, or size of the residual mass could provide prognostic information. Computed tomography (CT) examinations were carried out before, midway and after completion of chemotherapy in 37 patients with aggressive lymphoma
Over the past five years, moisture damages in external walls of wood frame structure and rendering on insulation as a cladding has been a widely debated subject which has received a lot of attention. In the light of this, the interest in an alternative construction method where rendering is applied on boards instead of insulation has increased. In this method, carrier boards are mounted on battens
Background. Giant cell tumor of bone (GCTB) is an aggressive primary osteolytic tumor. GCTB often involves the epiphysis, usually causing substantial pain and functional disability. Denosumab, a fully human monoclonal antibody against receptor activator of nuclear factor. kappa beta ligand (RANKL), is an effective treatment option for patients with advanced GCTB. This analysis of data from an ongo
In this chapter, the author analyses a new Swedish curriculum for schools that was presented in 2011 and came into effect the same year. Basically the focus in the subject of music is on playing music, creating music, and listening to music. But key citations within the subject of music show a return to some ideas from the beginning of the 20th century regarding nationalism, a Nordic ethnocentric
Prostate specific antigen (PSA) is a well-established tumor marker, which is frequently employed as model biomarker to develop and evaluate emerging quantitative proteomics techniques, partially due to wide access to commercialized immunoassays serving as "gold standard". We designed a multiple reaction monitoring (MRM) assay to detect PSA proteoforms in clinical samples (n=72), utilizing specific
We introduce a new dataset, Human3.6M, of 3.6 Million 3D Human poses, acquired by recording the performance of 11 subjects, under 4 different viewpoints, for training realistic human sensing systems and for evaluating the next generation of human pose estimation models. Besides increasing the size the current state of the art datasets by several orders of magnitude, we aim to complement such datas
A regional variational inverse modeling system for the estimation of European biogenic CO2 fluxes is presented. This system is based on a 50 km horizontal resolution configuration of a mesoscale atmospheric transport model and on the adjoint of its tracer transport code. It exploits hourly CO2 in situ data from 15 CarboEurope-Integrated Project stations. Particular attention in the inversion setup
This work demonstrates the capacity of a ballistic imaging instrument to suppress diffuse photons and improve image contrast, making it possible to view fluid structure in a spray where a fog of droplets occludes the near field. Analysis of the system is performed by means of a numerical system model. The model simulates light propagation and scattering in the measurement volume using a Monte Carl
Background Compared with placebo, prophylactic treatment with bisphosphonates reduces risk of skeletal events in patients with multiple myeloma. However, because of toxicity associated with long-term bisphosphonate treatment, establishing the lowest effective dose is important. This study compared the effect of two doses of pamidronate on health-related quality of life and skeletal morbidity in pa
The present study focuses on fragmented deglycosylated pyranose dehydrogenase (fdgPDH) from Agaricus meleagris recombinantly expressed in Pichia pastoris. Fragmented deglycosylated PDH is formed from the deglycosylated enzyme (dgPDH) when it spontaneously loses a C-terminal fragment when stored in a buffer solution at 4 degrees C. The remaining larger fragment has a molecular weight of similar to
