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Safe long-term storage of spent nuclear fuel (SNF) is one of the main issues in the field of nuclear safety. Burn-up credit application in criticality analysis of SNF reduces conservatism of usually used fresh fuel assumption and implies a positive economic impact for the SNF storage. Criticality calculations of spent nuclear fuel in the CONSTOR® RBMK-1500/M2 cask were performed using pre-generat

The capacity of risk prediction to guide management of CKD in underserved health settings is unknown. We conducted a retrospective cohort study of 28,779 adults with nondialysis-requiring CKD who received health care in two large safety net health systems during 1996-2009 and were followed for ESRD through September of 2011. We developed and evaluated the performance of ESRD risk prediction models

Labeling of proteins with deuterium (2H) is often necessary for structural biology tech-niques, such as neutron crystallography, NMR spectroscopy, and small-angle neutron scattering. Perdeuteration in which all protium (1H) atoms are replaced by deuterium is a costly process. Typ-ically, expression hosts are grown in a defined medium with heavy water as the solvent, which is supplemented with a de

Induced neurons (iNs), the product of somatic cells directly converted to neurons, are a way to obtain patient-derived neurons from tissue thatis easily accessible. Through this route, mature neurons can be obtained in a matter of a few weeks. Here, we describe a straightforward andrapid one-step protocol to obtain iNs from dermal fibroblasts obtained through biopsy samples from adult human donors

Objectives: ACST-2 is currently the largest trial ever conducted to compare carotid artery stenting (CAS) with carotid endarterectomy (CEA) in patients with severe asymptomatic carotid stenosis requiring revascularization. Methods: Patients are entered into ACST-2 when revascularization is felt to be clearly indicated, when CEA and CAS are both possible, but where there is substantial uncertainty

The interplay between cardiac sarcoplasmic Ca2+ATPase and phospholamban is a key regulating factor of contraction and relaxation in the cardiac muscle. In heart failure, aberrations in the inhibition of sarcoplasmic Ca2+ATPase by phospholamban are associated with anomalies in cardiac functions. In experimental heart failure models, modulation of the interaction between these two proteins has been

Smaller size and lower weight are always the targets of the power electronic product development. This work introduces two new topologies of auxiliary converters which have the feature of fewer components and fewer number of energy conversion stages comparing with the conventional auxiliary converter used in railway applications. The initial proposal of the proposed new topology is based on the id

The Parabolic Synthesis methodology is an approximation methodology for implementing unary functions, such as trigonometric functions, logarithms and square root, as well as binary functions, such as division, in hardware. Unary functions are extensively used in baseband for wireless/wireline communication, computer graphics, digital signal processing, robotics, astrophysics, fluid physics, games

Discussion on social media and their contribution to democratisation is dominated by scholarship on the use of social media in mobilizing and coordinating grassroots opposition in contentious movements (e.g., the Arab Spring). Such approach, however, fails to recognize the power dynamics underlying everyday uses of social media. To fill this gap, this article provides one of the first studies on t

Objective: The incidence of urinary bladder cancer (UBC) has increased in Sweden despite decreased smoking, indicating that other factors might be associated. The increased use of statin medication for elevated blood lipids might be one such influencing factor. The aim of the present study was to assess whether statins are afflicted with an increased incidence of UBC. Material and methods: Data fr

In the hardware development space, field programmable gate arrays (FPGAs) are in a unique position as a result of their in-field re-programmability. In contrast to the traditional design process of integrated circuits, FPGAs allow iterative de- velopment workflows closely resembling software development’s sprint-based pro- totyping. For this to work, efficient workflows for verification are key. V

Easy and low-threshold access is considered to be a major advantage of online services. In Sweden, social services in several municipalities strive to increase their accessibility by responding to anonymous users online. This paper raises the question about the nature of accessibility that the online social services entail. Two online platforms were studied: synchronous online chats and asynchrono

For magnetic field orientation of nonstructures to become a viable method to create high performance multifunctional nanocomposites, it is of paramount importance to develop a method that is easy to implement and that can induce long-range uniform nanostructural alignment. To overcome this challenge, inspired by low field nuclear magnetic resonance (NMR) technology, a highly uniform, high field st

Easy, low‐threshold access is widely regarded as a major advantage of online services. In Sweden, several municipalities are striving to increase the accessibility of their social services by responding to anonymous users online. This article considers the nature of the accessibility of these online services. Two online platforms were studied: (quasi‐)synchronous online chats and asynchronous onli

Coking is a common catalyst deactivation route in industrial processes involving carbonaceous species. While coking is easy to diagnose, this is often performed by bulk analysis. Understanding specific symptoms such as pore blockage and obstruction of active sites is especially challenging for technical catalysts and requires a spatially-resolved approach. Here a combination of ptychographic X-ray

Recent developments in computer graphics and hardware technology enable easy access to virtual reality headsets along with integrated eye trackers, leading to mass usage of such devices. The immersive experience provided by virtual reality and the possibility to control environmental factors in virtual setups may soon help to create realistic digital alternatives to conventional classrooms. The im

Radio signals are used broadly as navigation aids, and current and future terrestrial wireless communication systems have properties that make their dual-use for this purpose attractive. Sub-6 GHz carrier frequencies enable widespread coverage for data communication and navigation, but typically offer smaller bandwidths and limited resolution for precise estimation of geometries, particularly in e