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Transplants of fetal midbrain raphe neurons into the adult brain have been shown to promote recovery of complex behavioral deficits in several experimental models, but the mechanisms underlying these effects are only partially understood. In the present study, we have used a well-characterized model system to ascertain whether midbrain raphe graft can display behaviorally relevant changes in trans
It is well-known that the response to mechanical loading of nano-sized metal structures differs from what applies to the macroscopic scale, and often non-intuitive behaviors are revealed. Here beams of square cross section, containing defects in terms of voids and loaded in fatigue with R = 0 under displacement controlled conditions, are investigated. The structures under consideration are single-
A study of crack propagation paths in the situation where the crack is suppressed to open during growth due to high compressive forces has been performed. This problem was analyzed theoretically very recently by the authors and is here extended to involve a limited number of illustrative experimental results reported elsewhere in the literature. By analyzing the experimental crack growth patterns,
Diabetes mellitus (DM) incidence have been assessed in connection with air pollution exposure in several studies; however, few have investigated associations with source-specific local emissions. This study aims to estimate the risk of DM incidence associated with source-specific air pollution in a Swedish cohort with relatively low exposure. Individuals in the Västerbotten intervention programme
Background Closed-ended rating scales are the most used response format for researchers and clinicians to quantify mental states, whereas in natural contexts people communicate with natural language. The reason for using such scales is that they are typically argued to be more precise in measuring mental constructs; however, the respondents’ views as to what best communicates mental states are fre
Denna avhandling undersöker skapandet och omvandlingen av offentliga platser i Hongkong, en stad som är genomsyrad av nyliberala ideal och som under senare år har kännetecknats av betydande försämringar när det gäller demokratiska rättigheter och friheter. Som ett resultat av den nyliberala kapitalismens expansion har kommodifieringen av det urbana rummet inte bara förvärrats utan också blivit merThis thesis explores the production and transformation of public spaces in Hong Kong, a city that is steeped in neoliberal ideals and has seen substantial deterioration in terms of democratic rights and freedoms in recent years. As a result of the expansion of neoliberal capitalism, commodification of urban space has not only exacerbated, but also become more far-reaching and indiscriminate. While
Background: Exposure and Response Prevention (ERP) is a form of behavioural therapy for tics; however, its effectiveness remains uncertain. We aimed to evaluate the effectiveness of internet-delivered, therapist-supported, and parent-assisted ERP for treatment of tics in children and young people with Tourette syndrome or chronic tic disorder. Methods: This multicentre, parallel group, single-blin
Importance: Recent studies have questioned the presumed low-risk status of patients with asymptomatic nonsevere aortic stenosis (AS). Whether annual N-terminal pro-brain natriuretic peptide (NT-proBNP) measurements are useful for risk assessment is unknown. Objective: To assess the association of annual NT-proBNP measurements with clinical outcomes in patients with nonsevere AS. Design, Setting, a
Particle size can be an important variable to know in many different areas, be it smoke simulations, toxicity of materials or tests of face masks. Fires in a reduced oxygen environment can occur for ventilation-controlled fires or in areas with artificially lowered oxygen levels. The effects of lower concentrations of oxygen on heat release rate, smoke production etc. has been studied, but any eff
Skyldigheten att skydda, eller “R2P”, är en princip som har skapat vild debatt sedan den först introducerades av the International Commission on Intervention and State Sovereignty (ICISS) år 2001. Efter den positiva respons begreppet fick av FN:s medlemsstater under the World Summit Outcome 2005 verkade det som att FN rörde sig mot en ny tidsperiod, där arbetet för mänskliga rättigheter även skull
Rätten till medborgarskap kodifierad i artikel 15 i FN:s declaration om de mänskliga rättigheterna tolkas som rätten att ha rättigheter. Genom medborgarskap säkras tillgång till grundläggande mänskliga rättigheter. Personer som inte betraktas som medborgare i någon stat enligt dess lagar är de jure statslösa. Åtnjutandet av mänskliga rättigheter för de jure statslösa är följaktligen begränsad. FThe right to nationality codified in article 15 of the Universal Declaration of Human Rights is understood as the right to have rights. By possessing nationality, access to fundamental human rights is ensured. A person who is not considered a national of any state according to its laws is de jure stateless. De jure stateless persons are consequently impeded to enjoy such human rights. As of today
By building a strong brand that is favourably perceived by target customers, a firm can establish a competitive advantage that enables greater revenues and profitability. This is at least what the branding literature always has assumed, and something few marketing and brand managers seem to disagree with. When asked how exactly a brand can be charged with such great value, however, neither academi
The traditional restrictive attitude towards claim for compensation about non-pecuniary harms in both cause law and legislation become weaker even if the theoretically and practically reason behind the old exception-construction remain. This reason can best be explained by the thesis about incommensurability when it comes to compensate for some losses that money cannot compensate. To explain why t
China’s economic development has made a remarkable achievement over the past three decades. However, compared with other developed economies, it still mainly relies on coal resources as its primary energy. As country’s leading coal resources producer, Shanxi is now in an awkward position. A possible explanation is this region suffering “Resource Curse”: that the abundant resources did not bring ra
With increasing model complexity, sampling from the posterior distribution in a Bayesian context becomes challenging. The reason might be that the likelihood function is analytically unavailable or computationally costly to evaluate. In this thesis a fairly new scheme called approximate Bayesian computation is studied which, through simulations from the likelihood function, approximately simulates
Long time series of satellite remotely sensed Normalized Difference Vegetation Index (NDVI) as an indicator of vegetation greenness can be used in a broad range of research topics such as climate change, vegetation dynamics and desertification monitoring. The first phase of this study tests a practical method using Hyperion imagery onboard on Earth Observing-1 (EO1) spacecraft for simulation of MO
Popular Summary Wildfire events are expected to increase with the changing climate; thereby increasing atmospheric, economic, and human health impacts. A better understanding of the evolution of wildfire events can benefit regional meteorology models and global atmospheric models. Because of this, an attempt at modeling the evolution of wildfire was undertaken using 8 years of daily meteorologica
