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This paper focuses on the use of the Compound Past (CP) found in a set of epistolary letters from the 18th and 19th centuries' Uruguay. It is claimed that the CP already at this time encodes situations that are conceptualized within a temporal frame of indeterminacy. All the cases of CP in 66 letters are analyzed according to its contexts – with or without temporal determinants; in colocational en

A simplified approach to array optimization for the DC resistivity and induced polarization method

In this work a simplified approach to array optimization for the DC resistivity and induced polarization method have been created and tested. The optimization method uses the centre of the sensitivity function for the individual electrode configurations, called the mass centre, which is spread over the area of investigation, wherefrom the name Spread of Mass Centre (SMC). This array has been teste

Rotating Binary Bose-Einstein Condensates and Vortex Clusters in Quantum Droplets

Quantum droplets may form out of a gaseous Bose-Einstein condensate, stabilized by quantum fluctuations beyond mean field. Determining the ground state of a rotating binary condensate, we show that multiple singly quantized vortices may form in these droplets at moderate angular momenta in two dimensions. Droplets carrying these precursors of an Abrikosov lattice remain self-bound for certain time

Androgen Receptor in Stage I-II Primary Breast Cancer -Prognostic Value and Distribution in Subgroups

BACKGROUND/AIM: The value of androgen receptor (AR) in breast cancer has gained renewed interest as a prognostic and treatment predictive biomarker. The aims of this work were to study the associations and the prognostic value of AR in patients from two clinical cohorts.MATERIALS AND METHODS: Cohort 1 included 208 premenopausal, node-negative patients of whom 87% had received no adjuvant medical t

Simultaneous Conduction and Valence Band Quantization in Ultrashallow High-Density Doping Profiles in Semiconductors

We demonstrate simultaneous quantization of conduction band (CB) and valence band (VB) states in silicon using ultrashallow, high-density, phosphorus doping profiles (so-called Si:P δ layers). We show that, in addition to the well-known quantization of CB states within the dopant plane, the confinement of VB-derived states between the subsurface P dopant layer and the Si surface gives rise to a si

Markov modeling of peptide folding in the presence of protein crowders

We use Markov state models (MSMs) to analyze the dynamics of a β-hairpin-forming peptide in Monte Carlo (MC) simulations with interacting protein crowders, for two different types of crowder proteins [bovine pancreatic trypsin inhibitor (BPTI) and GB1]. In these systems, at the temperature used, the peptide can be folded or unfolded and bound or unbound to crowder molecules. Four or five major fre

Experimental Evidence for a Cluster Glass Transition in Concentrated Lysozyme Solutions

Lysozyme is known to form equilibrium clusters at pH ≈ 7.8 and at low ionic strength as a result of a mixed potential. While this cluster formation and the related dynamic and static structure factors have been extensively investigated, its consequences on the macroscopic dynamic behavior expressed by the zero shear viscosity η 0 remain controversial. Here we present results from a systematic in

Spatiotemporal coupling of attosecond pulses

The shortest light pulses produced to date are of the order of a few tens of attoseconds, with central frequencies in the extreme UV range and bandwidths exceeding tens of electronvolts. They are often produced as a train of pulses separated by half the driving laser period, leading in the frequency domain to a spectrum of high, odd-order harmonics. As light pulses become shorter and more spectral

Towards detection of glycoproteins using molecularly imprinted nanoparticles and boronic acid-modified fluorescent probe

Glycoproteins represent a group of important biomarkers for cancer and other life-threatening diseases. Selective detection of specific glycoproteins is an important step for early diagnosis. Traditional glycoprotein assays are mostly based on lectins, antibodies, and enzymes, biochemical reagents that are costly and require special cold chain storage and distribution. To address the shortcomings

Change of shell structure and magnetic moments of odd-N deformed nuclei towards the neutron drip line

Examples of the change of neutron shell structure in both weakly bound and resonant neutron one-particle levels in nuclei towards the neutron drip line are exhibited. It is shown that the shell-structure change due to the weak binding may lead to the deformation of those nuclei with the neutron numbers N approximate to 8, 20, 28 and 40, which are known to be magic numbers in stable nuclei. Nuclei

Signal processing algorithms for removing banding artifacts in MRI

In magnetic resonance imaging (MRI), the balanced steadystate free precession (bSSFP) pulse sequence has shown to be of great interest, due to its relatively high signal-to-noise ratio in a short scan time. However, images acquired with this pulse sequence suffer from banding artifacts due to offresonance effects. These artifacts typically appear as black bands covering parts of the image and they

Reconstruction Techniques and Finite Volume Schemes for Hyperbolic Conservation Laws

This thesis concerns the numerical approximation of the solutions to hyperbolic conservation laws. In particular the research work focuses on reconstruction techniques; the reconstruction being the key ingredient in modern finite volume schemes aiming to increase spatial order of accuracy. To better conform to the nature of the solutions to the hyperbolic problems, the reconstructing fu

An automated fluorescent single strand conformation polymorphism technique for high throughput mutation screening

OBJECTIVE: To develop a high throughput mutational detection method by multiple fluorescence-labeled polymerase chain reaction (PCR) products. METHODS: A total of 27 known mutations including 22 substitutions, 3 insertions (1, 2 and 7 bp) and 2 deletions (1 and 2 bp) in the hepatocyte nuclear factor (HNF)-4 alpha, glucokinase and HNF-1 alpha genes were tested. During nested PCR, amplified fragment

Biogas production from crop residues on a farm-scale level: is it economically feasible under conditions in Sweden?

Anaerobic digestion would enable the energy potential of agricultural crop residues such as sugar beet tops and straw to be harnessed. Sweden is so spread out that full utilisation of this potential by centralised slurry-based technology is difficult. It appears that simple but effective high-solids reactor systems have a better chance of being economically viable on a farm-scale level (50500 kW).

Enantioseparation of D- and L-amino acids by a coupled system consisting of an ion-exchange column and a chiral column and determination of D-aspartic acid and D-glutamic acid in soy products

A coupled system, consisting of a conventional ion-exchange column and a chiral column, was used for separation of the D- and L-enantiomers as constituents of an amino acid mixture. The ion-exchange column was connected to an amino acid analyser and the eluents necessary for the chiral column were delivered by an HPLC pump. With this on-line system the D- and L-forms of eight of the proteinogenic

Mapping the intracellular fraction of water by varying the gradient pulse length in q-space diffusion MRI

Finite gradient pulse lengths are traditionally considered a nuisance in q-space diffusion NMR and MRI, since the simple Fourier relation between the acquired signal and the displacement probability is invalidated. Increasing the value of the pulse length leads to an apparently smaller value of the estimated compartment size. We propose that q-space data at different gradient pulse lengths, but wi