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BACKGROUND: The currently used fragrance mix in the European baseline patch test series (baseline series) fails to detect a substantial number of clinically relevant fragrance allergies. OBJECTIVE: To investigate whether it is justified to include hydroxyisohexyl 3-cyclohexene carboxaldehyde (Lyral) and fragrance mix 2 containing hydroxyisohexyl 3-cyclohexene carboxaldehyde, citral, farnesol, coum
Purpose: To model prediction of undetected glaucoma in a predominantly white population, based on intraocular pressure (IOP) and subject age. Methods: In 1992–1997, a population screening for glaucoma was performed at Malmö University Hospital where individuals between 55–79 years of age (n = 46 614) living in Malmö, were invited to a free eye health examination. Recently examined patients were no
A recent core drilling in the geologically classical Fågelsång area resulted in a 58.70-m-long drill core through the lowermost Sandbian Sularp Shale, the Darriwilian Almelund Shale and Komstad Limestone, and part of the late Tremadocian to earliest Darriwilian Tøyen Shale. The shales contain zone index graptolites that are used for an update of the standard Darriwilian graptolite zone succession
Coiled-coil domains of intermediate filaments (IF) and prokaryotic IF-like proteins enable oligomerisation and filamentation, and no additional function is ascribed to these coiled-coil domains. However, an IF-like protein from Streptomyces reticuli was reported to display cellulose affinity. We demonstrate that cellulose affinity is an intrinsic property of the IF-like proteins FilP and Scy and t
Introduction: This review presents noteworthy advances in clinical and experimental Capsule Endoscopy (CE), focusing on the progress that has been reported over the last 5 years since our previous review on the subject. Areas covered: This study presents the commercially available CE platforms, as well as the advances made in optimizing the diagnostic capabilities of CE. The latter includes recent
Local agri-environmental schemes, including hedgerows, flowering strips, organic management, and a landscape rich in semi-natural habitat patches, are assumed to enhance the presence of beneficial arthropods and their contribution to biological control in fruit crops. We studied the influence of local factors (orchard management and adjacent habitats) and of landscape composition on the abundance
Bicuspid aortic valve (BAV) is the most common congenital cardiac abnormality, occurring in 1% to 2% of the general population. Adults with degenerative aortic valve (AV) disease have been shown to have an elliptical shaped AV annulus. The goal of this study was to investigate the shape of the aortic annulus in children with BAV, coarctation of the aorta (CoA) with or without BAV, and normal contr
In the process of compiling a new corpus of contemporary spoken British English, the London-Lund Corpus 2, we hit upon a construction used in the conversations recorded that had not previously been dealt with in the literature, namely the reactive what-x construction. Prompted by this discovery, we carried out a detailed analysis of its properties and constraints within the broad framework of Cogn
Up-regulation of carbonic anhydrase IX (CA IX) expression is an indicator of metastasis and associated with poor cancer patient prognosis. CA IX has emerged as a cancer drug target but development of isoform-specific inhibitors is challenging due to other highly conserved CA isoforms. In this study, a CA IXmimic construct was used (CA II with seven point mutations introduced, to mimic CA IX active
The present electrophysiological study investigated irregular versus regular verb form processing in Swedish during reading. In line with previous results from other languages, overregularized verbs, i.e. incorrect irregular stem + regular past tense suffix combinations (e.g. *stjäl + de ‘steal + past tense’), elicited a left-lateralized negativity (LAN) relative to correct irregulars (stal ‘stole
Clinical reasoning is proposed to represent cognitive processes, skills and decision-making aspects of nursing practice and is important for quality care. It has been suggested that the reasoning processes should be practiced during education to develop decision-making competence among nurses. The aim of the study was to explore and describe clinical reasoning processes at different times during s
Purpose: The aim of this study was to develop a deep learning-based method for segmentation of bones in CT scans and test its accuracy compared to manual delineation, as a first step in the creation of an automated PET/CT-based method for quantifying skeletal tumour burden. Methods: Convolutional neural networks (CNNs) were trained to segme
The objective of this work is to provide governmental agencies and the society a condensed overview of the current state of knowledge on the efficiency of applied restoration and remediation of areas affected by radioactive fallout. The most actual real-world case is the Fukushima accident in Japan in 2011: the accident and the following applied decontamination methods are in focus in this review
Background: There is limited knowledge about perceived challenges during the transition to adulthood among immigrant youths who are originally from Arabic-speaking countries but now residing in Sweden. Aim: The aim of this study was to describe self-identified problems encountered by immigrant youths with disabilities from Middle Eastern countries who were living in Sweden during their transition
Background: In addition to the established association between general obesity and breast cancer risk, central obesity and circulating fasting insulin and glucose have been linked to the development of this common malignancy. Findings from previous studies, however, have been inconsistent, and the nature of the associations is unclear.Methods: We conducted Mendelian randomization analyses to evalu
Purpose: Elevated copeptin, a vasopressin marker, is linked to metabolic disease, and obese rats with low-vasopressin concentration had a decreased risk of liver steatosis. We here investigated the association between copeptin and nonalcoholic fatty liver disease (NAFLD) and possible differences in copeptin concentration between ethnicities. Methods: In this cross-sectional study of 361 South Afri
Both numerical simulations and experiments were conducted in a heavy-duty DICI engine, with PRF81 as a gasoline surrogate, to investigate how the fuel stratification, auto-ignition and combustion are affected by the start of injection (SOI). The intake air temperature was adjusted to keep the combustion phasing constant when the SOI was swept from −100 to −20 oCA ATDC, covering different regimes o
Background: Roux-en-Y gastric bypass (RYGB) is an effective obesity treatment in adults and has become established in adolescents. Lower adherence to supplementation in adolescents confers a risk for long-term nutritional deficiencies. Objectives: To assess adherence to supplementation, micronutrient intake, and biochemistry in adolescents through 5 years after RYGB. Setting: University hospitals,
