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Background: Lead exposure is associated with cardiovascular disease. Atherosclerosis has been hypothesized to be one of the underlying mechanisms behind this association. Aim: To investigate whether lead exposure is associated with an increased risk of atherosclerosis in the carotid arteries in a large Swedish population-based cohort. Methods: We performed a cross-sectional study using data from t
This article is a response to the recent work of Michael F. Bird and Michael R. Whitenton, in which they argue that Hippolytus's De Christo et Antichristo provides a clear instance of a subjective genitive construction and unambiguously identifies as Jesus' death on the cross. However, in light of (1) a significant textual variant, and (2) the role that plays in Hippolytus's theology of martyrdom,
Context. The star cluster initial mass function is observed to have an inverse power law exponent around 2, yet there is no consensus on what determines this distribution, and why some variation is observed in different galaxies. Furthermore, the cluster formation efficiency (CFE) covers a range of values, particularly when considering different environments. These clusters are often used to empir
Numerous electronic travel aids (ETAs) to increase the mobility of blind or low-vision (BLV) individuals have been proposed. However, the lack of established and well-motivated methods, and of recruiting enough BLV test participants, keeps a successful aid illusory. To combat this, a new aid-agnostic questionnaire focused on mobility, the Desire of Use Questionnaire for Mobility of BLV individuals
A growing body of research supports stromal tumour-infiltrating lymphocyte (TIL) density in breast cancer to be a robust prognostic and predicive biomarker. The gold standard for stromal TIL density quantitation in breast cancer is pathologist visual assessment using haematoxylin and eosin-stained slides. Artificial intelligence/machine-learning algorithms are in development to automate the stroma
Food sharing is increasingly making its way in cities, offering new opportunities to tackle inequalities and shape more sustainable and resilient urban and peri-urban food systems. However, food sharing initiatives face multiple policy barriers that hinder its potential. Drawing on an international review of existing studies of Food Sharing Initiatives (FSI) governance, this first policy brief of
Plant pathogens are challenged by host-derived iron starvation or excess during infection, but the mechanism of plant pathogens rapidly adapting to the dynamic host iron environments to assimilate iron for invasion and colonization remains largely unexplored. Here, we found that the GATA transcription factor SreC in Curvularia lunata is required for virulence and adaption to the host iron excess e
Purpose: The apparel and textile sector poses a significant environmental challenge due to its substantial contribution to pollution in the form of air, water and soil pollution. To combat these issues, the adoption of sustainable practices is essential. This study aims to identify and analyse the barriers that hinder the progress of sustainability in the apparel and textile industry. By consultin
The study of atmospheric processes related to climate requires a multidisciplinary approach, encompassing physics, chemistry, meteorology, forest science, and environmental science. The Academy of Finland Centre of Excellence in atmospheric sciences (CoE ATM) responded to that need for 18 years and produced extensive research and eloquent results, which are summarized in this review. The work in t
Semi-coherent Y2O3 (yttria) inclusions are identified in high quality epitaxial YBa2Cu3Ox (YBCO) thin films by using transmission electron microscopy and energy dispersive X-ray analyses. Magnetization measurements show enhanced flux pinning in films containing an increasing number density of inclusions. The inclusions are incorporated into the films without disturbing the YBCO structure appreciab
Background: The understanding of inhaled particle respiratory tract deposition is a key link to understand the health effects of particles or the efficiency for medical drug delivery via the lung. However, there are few experimental data on particle respiratory tract deposition, and the existing data deviates considerably when comparing results for particles > 1 μm. Methods: We designed an experim
The production of prompt Λc+ baryons has been measured at midrapidity in the transverse momentum interval 0
The catalytic subunit of polymerase ζ is encoded from the Rev3 gene. The enzyme is conserved through eukaryotic evolution and its main function appears to be translesion synthesis (TLS) over damaged bases that stall DNA replication. In non-vertebrate cells, inactivation of polymerase ζ results in a moderate hypersensitivity to DNA damage but no proliferative defect in the absence of exogenous dama
Scientific uncertainty is clearly a prominent hurdle in public health policy and the policy choices made to tackle this uncertainty are largely left to the Member States. Indeed, the Court of Justice of the EU has long since held that the health and the life of humans rank first among the interests that Member States can legitimately pursue - even if they restrict the market freedoms in doing so -
