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Journal of Parkinson’s Disease xx (2022) x–xx DOI 10.3233/JPD-223452 IOS Press 1 Review A Combined -Synuclein/Fibril (SynFib) Model of Parkinson-Like Synucleinopathy Targeting the Nigrostriatal Dopamine System Anders Björklund∗, Fredrik Nilsson, Bengt Mattsson, Deirdre B. Hoban and Malin Parmar Developmental and Regenerative Neurobiology, Department of Experimental Medical Science, Wallenberg Neu
LL_SMAA25_rev170707 Litteraturlista för Personligt ledarskap, 7,5 hp, (SMAA25) Litteraturlistan är fastställd av styrelsen för institutionen för service management och tjänstevetenskap 2015-11-25, reviderad 2017-07-07. Litteraturlistan börjar gälla 2017-08-01. Ben-Shahar, Tal. (2009). Lyckligare: Den största belöningen i ditt liv. Stockholm: Natur och kultur. [203 sidor. ISBN 9789127119628] eller
https://www.ses.lu.se/sites/ses.lu.se/files/ll_smaa25_rev170707.pdf - 2026-07-01
Sammanfattning Titel: Miljöredovisning i börsnoterade företag år 2000 Ämne: Magisteruppsats i företagsekonomi 10 poäng Författare: Camilla Björk och Lislott Borglin Handledare: Fredrik Ljungdahl Syfte: Vi avser att beskriva och analysera svenska börsföretags miljöredovisning i monetära termer i årsredovisningar och miljöredovisningar avseende räkenskapsåret 2000. Vi kommer också att jämföra företa
Popular Abstract in Swedish Elektrostatiske vekselvirkninger mellem biomolekyler er vigtige, ikke bare i biologiske systemer, men også i flere tekniske sammenhænge. I denne afhandling studereres en række forskellige egenskaber, relevant for særligt proteiner. Således har vi ved hjælp af molekylær simulering undersøgt hvorledes proteiner vekselvirker med protoner, salte, andre peptider og proteinerElectrostatic interactions in bio-molecular systems are important not only in the living cell but also in more technical applications. Using molecular simulation as well as approximate theories the properties of a number of aqueous protein solutions have been studied. This includes interactions with other proteins, protons, charged membranes as well as flexible polyelectrolytes. The focus is on el
ObjectiveTo examine the frequency and characteristics of headaches and their association with global disease activity and health-related quality of life (HRQOL) in patients with systemic lupus erythematosus (SLE). MethodsA disease inception cohort was assessed annually for headache (5 types) and 18 other neuropsychiatric (NP) events. Global disease activity scores (SLE Disease Activity Index 2000
Barley is one of the most important crops in the world. Although it is mainly used as the raw material for the production of beer and animal feed, it has recently attracted interest from nutritionists and consumers, due to its high content of dietary fibre, especially β-glucan, and its relation to various positive health effects. The proposed mechanisms behind the health effects are the formation
In vivo proton magnetic resonance spectroscopy (1H-MRS) data often exhibit baselines or low-amplitude signal variations resulting from residual water, imperfectly suppressed lipids, low-amplitude metabolites not considered for fitting, and other features not represented in a basis set. While multitudinous approaches exist to model these baselines in 1H-MR spectral analysis, many continue to lack s
BACKGROUND: Patients undergoing hepato-pancreato-biliary surgery are typically preoperatively assessed using the American Society of Anesthesiologists (ASA) classification, which is also used for case-mix adjustment when comparing centre outcomes. Studies determining the inter-rater variability of the ASA classification within hepato-pancreato-biliary surgery are currently lacking.METHODS: An inte
BackgroundPostural instability is considered a late complication of Parkinson’s disease (PD). However, growing evidence shows that balance and gait problems may occur early in the disease.ObjectiveTo describe balance, gait, and falls/near falls in persons with newly diagnosed, untreated PD (“de novo”), and to compare this with persons with mild-moderate PD (Later PD). In addition, we evaluated dif
Background: Topical negative pressure (TNP), widely used in wound therapy, is known to stimulate wound edge blood flow, granulation tissue formation, angiogenesis, and revascularization. We have previously shown that application of a TNP of -50 mmHg to the myocardium significantly increases microvascular blood flow in the underlying tissue. We have also shown that a myocardial TNP levels between -
Popular Abstract in Swedish POPULÄRVETENSKAPLIG SAMMANFATTNING PÅ SVENSKA Graviditetsdiabetes (GDM) definieras som ett diabetestillstånd som upptäcks under graviditet. Ofta orsakas detta tillstånd av de hormonförändringar som uppträder under graviditet vilka medför en ökad insulinresistens, dvs. ett ökat motstånd mot insulinets effekter. Diagnosen GDM utesluter dock inte diabetes av annan orsak soThe aims of this work were to determine the prevalence of postpartum diabetes among women with gestational diabetes mellitus (GDM) in a prospective study 5 years postpartum; to characterize these women according to insulin secretion, insulin sensitivity, autoimmunity and genetics; and to identify possible markers and predictors for the development of manifest diabetes. The subjects were recruited
Popular Abstract in Swedish Svår alfa-1antitrypsinbrist (AAT-brist), s.k. PiZZ, är ett ärftligt tillstånd som har en hög förekomst i Sverige, cirka 1/1600. Bristen innebär ökad risk för utveckling av kroniskt obstruktiv lungsjukdom (KOL), speciellt hos rökare. Leversjukdom är också relativt vanlig och kan förekomma såväl i barndomen som i hög ålder. Levercirros (skrumplever) och levercancer är öveSevere alpha-1 antitrypsin deficiency (AATD) is a genetic disorder associated with increases risk of developing of chronic obstructive lung disease and liver disease. The Swedish National Registry for individuals with severe AATD was started 1991.Up to October 2008, a total of 1349 individuals were included in the registry. The aims of the studies in this thesis which bases on AATD registry are to
Bakgrund: Anestesisjuksköterskor arbetar i en högteknologisk miljö med mycket engångsmaterial av plast. Anestesislangar som används är av plast och ofta avsedda för engångsbruk. Enligt ICN:s etiska kod ska alla sjuksköterskor arbeta för FN:s globala mål för hållbar utveckling, att minska plastanvändningen är en central fråga. Syfte: Studiens syfte var att undersöka anestesisjuksköterskans uppfat
