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An increased frequency of droughts due to anthropogenic climate change can lead to considerable stress for soil microorganisms and their functioning within northern peatlands. A better understanding of the diversity and relative abundance of methane producing and oxidizing taxa, and their functional genes, can help predict the functional potential of peatlands and how the microorganisms respond to
This chapter highlights how implementing circular economy principles can help companies working with sustainability to move from a reductionist and waste management approach to marketing competitive circular value propositions that intentionally design out waste (e.g. emissions and pollution) by rethinking, reinventing and redesigning the value chain. Schijvens, a Dutch family-owned corporate fash
The extent of vegetation openness in past European landscapes is widely debated. In particular, the temperate forest biome has traditionally been defined as dense, closed-canopy forest; however, some argue that large herbivores maintained greater openness or even wood-pasture conditions. Here, we address this question for the Last Interglacial period (129,000–116,000 years ago), before Homo sapien
BACKGROUND: Contact allergy rates of linalool and limonene hydroperoxides (HPs) have increased.OBJECTIVES: To demonstrate the patterns of simultaneous positive patch test (PT) reactions and prevalences of multiple contact allergies (MCAs) in patients with contact allergy to linalool and/or limonene HPs.METHODS: A retrospective analysis of consecutive dermatitis patients in 2015-2020 was performed.
X-ray phase contrast imaging (X-PCI) is a powerful technique for high-resolution, three-dimensional imaging of soft tissue samples in a non-destructive manner. In this technical report, we assess the quality of standard histopathological techniques performed on formalin-fixed, paraffin-embedded (FFPE) human tissue samples that have been irradiated with different doses of X-rays in the context of a
Autoethnography is no longer a marginal anthropological practice but one that is taught at many universities worldwide. And this approach to empirical knowledge gathering and anthropological analysis forms the basis for hundreds if not thousands of publications, many of which are well cited and widely celebrated. The success of autoethnography is surely a cause for celebration. It is, however, als
Multiple DNA polymerases exist in eukaryotes. Polymerases α, δ and ε are mainly responsible for chromosomal DNA replication in the nucleus and are required for proliferation. In contrast, the repair polymerases β and η are not essential for cellular proliferation in yeast or mice, but a lack of either polymerase can lead, respectively, to defects in base excision repair or the ability to replicate
Managed bee species provide essential pollination services that contribute to food security worldwide. However, managed bees face a diverse array of threats and anticipating these, and potential opportunities to reduce risks, is essential for the sustainable management of pollination services. We conducted a horizon scanning exercise with 20 experts from across Europe to identify emerging threats
Bacterial lipopolysaccharide (LPS) induces rapid protein aggregation in human wound fluid. We aimed to characterize these LPS-induced aggregates and their functional implications using a combination of mass spectrometry analyses, biochemical assays, biological imaging, cell experiments, and animal models. The wound-fluid aggregates encompass diverse protein classes, including sequences from coagul
Strategisk kommunikation har länge förföljts av ryktet att vara omoraliskt, ofta använt synonymt med nedsättande ord som sofistik och propaganda. Forskare inom samhällsvetenskapen har tränats att acceptera denna beskrivning av strategisk kommunikation som en normativ utgångspunkt, genom inflytelserika teorier som Habermas diskursetik och metodologier som kritisk diskursanalys. Denna avhandling utmStrategic communication has long suffered from a reputation of immorality, often being conflated with derogatory terms such as sophistry and propaganda. Scholars in the social sciences have been trained to accept this moralizing idea of strategic communication as a normative point of departure, through influential theories such as Habermas’ discourse ethics and methodological approaches such as cr
Background Impulse oscillometry (IOS) is sensitive in detecting lung function impairment. In small studies, impaired IOS relates better to respiratory symptoms than spirometry. We studied how IOS related to spirometry and respiratory symptoms in a large population of individuals (n=10 360) in a cross-sectional analysis. Methods Normal values for IOS and spirometry were defined in healthy, never-sm
Objective: We aimed to test whether region-specific factors, including spatial expression patterns of the tau-encoding gene MAPT and regional levels of amyloid positron emission tomography (PET), enhance connectivity-based modeling of the spatial variability in tau-PET deposition in the Alzheimer disease (AD) spectrum. Methods: We included 685 participants (395 amyloid-positive participants within
Background: Respiratory virus infections are main triggers of asthma exacerbations. Tezepelumab, an anti-TSLP mAb, reduces exacerbations in patients with asthma, but the effect of blocking TSLP on host epithelial resistance and tolerance to virus infection is not known. Aim: To examine effects of blocking TSLP in patients with asthma on host resistance (IFNβ, IFNλ, and viral load) and on the airwa
Background The efficacy of the interception and purification mechanism for low-dose toxic contaminants in riverbeds, which serve as a link between surface water and groundwater, is of paramount importance in ensuring groundwater safety, particularly considering the replenishment of reclaimed water. The specific objective of this work is to identify the variation of interception efficiency and tran
The use of loess as a resource for paleoclimatic research is quite well established. In Serbia, a significant number of loess sequences have been preserved in old brickyards. The results of the previously conducted research indicate extremely valuable data that enable a better understanding of the mid- to late Pleistocene climatic evolution in this part of Europe, as well as human dispersal from A
Why are Western governments not retrieving detained minor nationals from Al-Hol’s purgatory-like conditions? This article shows, under international human rights law, that the status of detained children as rights bearers is uncontroversial, as is their right to positive protection. We raise issues from recent debate on the securitisation of geopolitics in the relationship between the Middle East
Forskning om mobbning i skolan har ägnat avsevärd uppmärksamhet åt att undersöka vilken roll åskådare (elever som bevittnar mobbning eller vet att den pågår) spelar i att påverka antalet mobbningsfall. Omfattande forskningsfynd har visat att ingripande från kamrater är väsentligt för att minska mobbningsbeteenden och följaktligen har efterföljande studier sökt avgöra vilka faktorer som bidrar tillResearch on school bullying has devoted a considerable amount of attention to investigating the roles of bystanders – the students who witness bullying or know that it is occurring – in bullying episodes. Numerous findings have shown that peer intervention is essential for reducing bullying behaviors; consequently, subsequent studies have examined which factors contribute to increasing the number
