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Mechanistic Studies of Dinuclear Metalloenzymes - A Model Approach

Popular Abstract in Swedish Enzymer är viktiga ämnen i naturen. Vi talar då och då om att vi förbränner vår mat. Trots detta känner vi oss oftast inte särskilt varma, i alla fall inte så att det bränns. Visst bränner vi vår mat. Socker omvandlas till koldioxid och vatten precis som om vi hade eldat upp det utanför kroppen. Skillnanden är att kroppen omvandlar sockret långsammare och mer kontrollerWith the goal to study the mechanisms of dinuclear metalloenzymes, a new line of synthetic and computational models were prepared and studied. Mixed imidazole and carboxylate multidentate complexes were synthesized to better simulate carboxylate-rich ligand environments. Of the compounds, which showed to be the most useful, were one symmetric and the other one asymmetric and in both cases they wer

The complex world of proteins: Structure, function, and oligomerization of frataxin

Popular Abstract in Swedish Bakgrund Järn (med den kemiska beteckningen Fe, från latinets ferrum) är känt för de flesta som en beståndsdel i till exempel stål. Det många inte vet är att järn är nödvändigt för liv, så som det ser ut på jorden idag. Men det finns en annan sida av myntet: järn kan nämligen också vara giftigt. Som de allra flesta känner till rostar järn i närvaro av syre och vatten.Patients suffering from the deadly progressive neurodegenerative disease Friedreich's ataxia have reduced levels of expression of the protein frataxin. Yeast frataxin has been extensively studied in vitro, and has been shown to deliver iron to heme and iron-sulfur cluster biosynthesis, as well as to oligomerize in the presence of iron. In this dissertation metal-dependent oligomerization of fratax

Sustained versus standard inflations during neonatal resuscitation to prevent mortality and improve respiratory outcomes

Background: At birth, infants' lungs are fluid-filled. For newborns to have a successful transition, this fluid must be replaced by air to enable effective breathing. Some infants are judged to have inadequate breathing at birth and are resuscitated with positive pressure ventilation (PPV). Giving prolonged (sustained) inflations at the start of PPV may help clear lung fluid and establish gas volu

Social skills training for attention deficit hyperactivity disorder (ADHD) in children aged 5 to 18 years

Background: Attention deficit hyperactivity disorder (ADHD) in children is associated with hyperactivity and impulsivity, attention problems, and difficulties with social interactions. Pharmacological treatment may alleviate the symptoms of ADHD but this rarely solves difficulties with social interactions. Children with ADHD may benefit from interventions designed to improve their social skills.We

Oral and sublingual immunotherapy for egg allergy

Background: Clinical egg allergy is a common food allergy. Current management relies upon strict allergen avoidance. Oral immunotherapy might be an optional treatment, through desensitization to egg allergen. Objectives: To determine the efficacy and safety of oral and sublingual immunotherapy in children and adults with immunoglobulin E (IgE)-mediated egg allergy as compared to a placebo treatmen

Aspects of ethnicity on blood pressure regulating mechanisms and kidney function in a defined population

Background: Middle Eastern immigrants represent a growing population in Sweden today. This group are at higher risk for type 2 diabetes than the native population, but are also shown to exhibit unique properties; despite an abundance in traditional cardiometabolic risk factors such as obesity, dearranged blood lipids and diminished physical acitivity, this group seem to exhibit lower blood pressur

The Influence of Level of Education on Instrumental Activities of Daily Living in Patients with Alzheimer’s Disease.

Background: According to the “brain-reserve hypothesis” in Alzheimer’s disease (AD), patients with more years of education are expected to have higher cognitive status during adulthood. Hence, they might have a relatively larger burden of AD pathology and a more advanced level of the disease when dementia is clinically evident. Higher educated people would also be expected to perform better on sta

Do Fixed or Mobile Bearing Implants Have Better Survivorship in Medial Unicompartmental Knee Arthroplasty? A Study From the Australian Orthopaedic Association National Joint Replacement Registry

BACKGROUND: During the last 5 years, there has been an increase in the use of unicompartmental knee arthroplasty (UKA) to treat knee osteoarthritis in Australia, and these account for almost 6% of annual knee replacement procedures. However, there is debate as to whether a fixed bearing or a mobile bearing design is best for decreasing revision for loosening and disease progression as well as impr

Weight reduction intervention for obese infertile women prior to IVF : A randomized controlled trial

STUDY QUESTION Does an intensive weight reduction programme prior to IVF increase live birth rates for infertile obese women? SUMMARY ANSWER An intensive weight reduction programme resulted in a large weight loss but did not substantially affect live birth rates in obese women scheduled for IVF. WHAT IS ALREADY KNOWN Among obese women, fertility and obstetric outcomes are influenced negatively wit

Arrhythmias in Older People: Focusing on Atrial Fibrillation. Epidemiology and impact on daily Life.

Older people with arrhythmias comprise a large group requiring complex care, posing many healthcare challenges. Rapid growth of the older population demands a better understanding of the needs of this patient group. The aim of this thesis was to investigate arrhythmia prevalence, incidence, survival, and experiences from the perspective of a geriatric population (aged 60+ years), and to examine th

Distansarbete - En arbetsrättslig analys av integritetsskydd och arbetsmiljö vid distansarbete i svensk rätt och Europarätt

Under Covid-19 pandemin har distansarbete varit en central del i strategin för att minska smittspridningen av viruset. Före pandemin arbetade endast 5 % av arbetstagarna inom EU på distans regelbundet. När pandemin bröt ut ökade andelen distansarbetare inom EU till nästan 40 %. Den snabba omställningen till distansarbete har aktualiserat flera arbetsrättsliga frågor. Syftet med denna uppsats är atDuring the Covid-19 pandemic, telework has been a central part of the strategy to reduce the spread of the virus. Before the pandemic, only 5% of EU workers worked remotely on a regular basis. When the pandemic broke out, the proportion of employees working remotely in the EU increased to almost 40%. The rapid transition to telework has raised several issues of labor law. The purpose of this thesi

The mammalian brain in the electromagnetic fields designed by man with special reference to blood-brain barrier function, neuronal damage and possible physical mechanisms

Life oil earth was formed during billions of years, exposed to, and shaped by the original physical forces such as gravitation, cosmic irradiation, atmospheric electric fields and the terrestrial magnetism. The Schumann resonances at 7.4 Hz are all example of oscillations possibly important for life.(1)) The existing organisms are created to function in harmony with these forces. However, in the l

Cumulative live birth rates under three consecutive IVF/ICSI treatment cycles are reduced in women with endometriosis and/or adenomyosis diagnosed by ultrasonography

STUDY QUESTIONDoes endometriosis and/or adenomyosis, diagnosed using the International Deep Endometriosis Analysis (IDEA) group and the Morphological Uterus Sonographic Assessment (MUSA) group revised definitions, impact cumulative live birth rates (CLBR) after three consecutive IVF or ICSI treatments?SUMMARY ANSWERWomen with endometriosis and/or adenomyosis, as diagnosed using transvaginal ultras

Piccini et al ann neurol 2000 0

Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts Delayed Recovery of Movement-Related Cortical Function in Parkinson’s Disease after Striatal Dopaminergic Grafts Paola Piccini, MD,* Olle Lindvall, MD, PhD,† Anders Björklund, MD, PhD,‡ Patrik Brundin, MD, PhD,§ Peter Hagell, RN, BSc,† Roberto Ceravolo, MD,* Wolfgang Oertel, MD,i Niall

https://www.wnc.lu.se/sites/wnc.lu.se/files/piccini_et_al_ann_neurol_2000_0.pdf - 2026-05-30

Beslut-delegationsordning-20260212

FÖRSÄTTSSIDA STYRDOKUMENT Riktlinjer för fördelning av beslutsbefogenheter samt arbetsformer vid Samhällsvetenskapliga fakulteten Typ av styrdokument: Riktlinjer Definition av typen av styrdokument: Enligt universitetets riktlinjer för styrdokument (STYR 2024/1601) fastställer riktlinjer hur någon ska eller bör handla inom det område riktlinjerna omfattar. En ska-regel ska följas medan en bör-rege

https://www.sam.lu.se/internt/sites/sam.lu.se.internt/files/2026-02/beslut-delegationsordning-20260212.pdf - 2026-05-30

Råd Och Anvisningar 2025

Råd och anvisningar för uppsatsarbete Socialhögskolan vid Lunds universitet September 2025 Förord Arbetet med Råd och anvisningar för uppsatsarbete inleddes av Katarina Jacobsson, som var huvudansvarig för den första upplagan (2008) och därefter höll i den löpande översynen. Den första upplagan byggde bland annat vidare på tidigare uppsatsanvisningar och grunder för bedömningskriterier formulerade

https://www.soch.lu.se/sites/soch.lu.se/files/2025-09/R%C3%A5d%20och%20anvisningar%202025.pdf - 2026-05-30

Verksamhetsberattelse-2015

Centrum för handelsforskning vid Lunds universitet VERKSAMHETSBERÄTTELSE | 2015 2 VERKSAMHETSBERÄTTELSE CENTRUM FÖR HANDELSFORSKNING 2015 3 VERKSAMHETSBERÄTTELSE CENTRUM FÖR HANDELSFORSKNING 2015 Inledning Centrum för handelsforskning – det andra året Med denna andra årsrapport från Centrum för handelsforsk- ning markerar vi ytterligare ett verksamhetsår. Under detta år har vi arbetat med att slut

https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-01/verksamhetsberattelse-2015.pdf - 2026-05-30

Råd Och Anvisningar 2024

Råd och anvisningar för uppsatsarbete Socialhögskolan vid Lunds universitet Januari 2024 Förord Arbetet med Råd och anvisningar för uppsatsarbete inleddes av Katarina Jacobsson, som var huvudansvarig för den första upplagan (2008) och därefter höll i den löpande översynen. Den första upplagan byggde bland annat vidare på tidigare uppsatsanvisningar och grunder för bedömningskriterier formulerade a

https://www.soch.lu.se/sites/soch.lu.se/files/2024-02/R%C3%A5d%20och%20anvisningar%202024.pdf - 2026-05-30

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c o n te n tmodevetarnas bästa julklappstips Redaktörerna Julia & Sandra två dikter Tindra Liljeberg Nilsson månadens media & ting Tobias Johansson en dag fylld med lärorika gästföreläsningar Redaktörerna Julia & Sandra nobelfesten 2024: tomm & tobb tycker till Tobias Johansson & Tommy Kali 01 02 03 04 05 Utgivare Modevetenskapliga studierådet Redaktörer Sandra Ghirmasion & Julia Lundgren Art Dire

https://www.kultur.lu.se/fileadmin/user_upload/kultur/Utbildning/Mode_maanadsbrev/Modebrev_December_2024_.pdf - 2026-05-25