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OBJECTIVE: To study intra-aneurysm sac pressure and subsequent abdominal aortic aneurysm (AAA) diameter changes in patients without endoleaks that remain unchanged in AAA diameter more than 1 year after endovascular aneurysm repair (EVAR). METHODS: A total of 23 patients underwent direct intra-aneurysm sac pressure (DISP) measurements 16 months (IQR: 14-35 months) after EVAR. Tip-pressure sensors
Dynamic global vegetation models (DGVMs) are designed for the study of past, present and future vegetation patterns together with associated biogeochemical cycles and climate feedbacks. However, most DGVMs do not yet have detailed representations of permafrost and non-permafrost peatlands, which are an important store of carbon, particularly at high latitudes. We demonstrate a new implementation o
BACKGROUND: Phosphoglucose isomerase (PGI, EC 5.3.1.9) is an essential metabolic enzyme in all eukaryotes. An earlier study of the PgiC1 gene, which encodes cytosolic PGI in the grass Festuca ovina L., revealed a marked difference in the levels of nucleotide polymorphism between the 5' and 3' portions of the gene.METHODS: In the present study, we characterized the sequence polymorphism in F. ovina
Background: The prognosis of Alzheimer’s disease (AD) might be influenced by many sociodemographic and clinical factors. Previous studies have investigated the main effects of critical predictors but few have analyzed potential interactions. We have studied the long-term cognitive outcome, nursing home placement (NHP) and mortality by interactions between factors in cholinesterase inhibitor (ChEI)
Malignant melanoma is a heterogeneous, malignant neoplastic disease, most often originating in the skin. Melanoma is characterized by a high mutational load and has a vastly variable prognosis, depending on disease stage. Genetic aberrations in the mitogen-activating protein kinase (MAPK) pathway are important in melanoma, of which mutations in BRAF and NRAS are the most common. Additionally, recu
The incidence of narcolepsy type 1 (NT1) increased in Sweden following the 2009-2010 mass-vaccination with the influenza Pandemrix-vaccine. NT1 has been associated with Human leukocyte antigen (HLA) DQB1*06:02 but full high-resolution HLA-typing of all loci in vaccine-induced NT1 remains to be done. Therefore, here we performed HLA typing by sequencing HLA-DRB3, DRB4, DRB5, DRB1, DQA1, DQB1, DPA1
All personal ska ta del av nedanstående information och föreskrifter. Avsikten med föreskrifterna är att minimera risker för ohälsa och olycksfall. Informationen är hämtad från lu.se. Mer information samt information om händelserapportering kan du hitta på lu.se/emergency SJUKDOM OCH OLYCKSFALL Första hjälpen-material finns på expeditionen och i studentutrymmet på våningsplan 1. Institutionen har
https://www.keg.lu.se/sites/keg.lu.se/files/sakerhetsbroschyr_anstallda.pdf - 2026-06-08
BACKGROUND: Postmortem MRI has opened-up avenues to study brain structure at ultra high-resolution revealing details not possible to observe with in vivo MRI. Here, we present a novel package (purple-mri) which performs tissue segmentation, anatomical parcellation and spatial normalization of postmortem MRI. Additionally, we provide a framework to perform point-wise surface-based group-level studi
Background: Depression is a risk factor for type 2 diabetes (T2D) and cardiovascular disease (CVD). The aims were to explore the prevalence of depression, anxiety, antidepressant use, obesity, Hemoglobin A1c > 64 mmol/mol, life-style factors, pre-existing CVD, in patients with newly diagnosed T2D; to explore associations with depression; and to compare with Swedish general population data. Methods
Objectives: The aim of this study was to investigate genetic outcomes, analyze the family experience, and describe the process of implementing genetic sequencing for children with profound sensorineural hearing loss (SNHL) at a tertial audiological center in southern Sweden. Design: This is a prospective pilot study including eleven children with profound bilateral SNHL who underwent cochlear impl
Background: Hepatitis B virus infection is a global health problem with the highest prevalence in East Asia and Sub-Saharan Africa. The majority of infected people, including healthcare workers are unaware of their status. This study is aimed to determining seroprevalence of hepatitis B virus infection and associated factors among healthcare workers in northern Tanzania. Methods: This cross-sectio
To assess the biodiversity consequences of contemporary land-use trends in Northern Europe, where agriculture is being replaced by forestry, we need a better knowledge of the contributions of constituting habitats to biodiversity. Here, we use purposefully collected data from 87 sites to model how agricultural habitats, including semi-natural pastures, sown temporary grassland (leys), cereal crops
BACKGROUND: The major risk factors for atherosclerotic cardiovascular disease differ by race or ethnicity but have largely been defined using populations of European ancestry. Despite the rising prevalence of cardiovascular disease in Africa there are few related data from African populations. Therefore, we compared the association of established cardiovascular risk factors with carotid-intima med
The COVID-19 accelerated shift towards hybrid workspaces places major pressure onworkplace communities and culture. This study explores the emergence of a collaborative academic workspace, which is still in the real estate development phase. The aim is to establish preconditions for community building, and the relationship between the community and the physical space. The study employs a qualitati
Northern ecosystems, encompassing boreal forests, tundra, and permafrost areas, are increasingly affected by the amplified impacts of climate change. These ecosystems play a crucial role in determining the global carbon budget. To improve our understanding of carbon uptake in these regions, we evaluate the effectiveness of employing the physically-based Plant Phenology Index (PPI) to estimate gros
Dune slacks are biodiverse seasonal wetlands within sand dune systems, strongly influenced by the dynamics of the local groundwater regime. Future climate predictions indicate strong adverse impact on the hydrology and therefore ecology of these wetland ecosystems. In this study we aimed to find the most appropriate hydrological and ecological indicators to summarise dune slack plant community res
Due to ongoing climate change, methane (CH4) emissions from vegetated wetlands are projected to increase during the 21st century, challenging climate mitigation efforts aimed at limiting global warming. However, despite reports of rising emission trends, a comprehensive evaluation and attribution of recent changes remains limited. Here we assessed global wetland CH4 emissions from 2000-2020 based
Purpose (the aim of the study): There is limited evidence on psychometric properties of EQ-5D-5L among people with osteoarthritis (OA) undertaking non-surgical treatment. The aim of the current study was to evaluate the psychometric properties of the EQ-5D-5L among individuals with knee or hip OA participating in a digitally delivered education and exercise therapy.Methods: Secondary analysis of d
IMPORTANCE: Perforated colonic diverticulitis usually requires surgical resection, which is associated with significant morbidity. Cohort studies have suggested that laparoscopic lavage may treat perforated diverticulitis with less morbidity than resection procedures. OBJECTIVE: To compare the outcomes from laparoscopic lavage with those for colon resection for perforated diverticulitis. DESIGN, S
BACKGROUND: Despite the detrimental impact of abnormal glucose metabolism on cardiovascular prognosis after myocardial infarction (MI), diabetes is both underdiagnosed and undertreated. We investigated associations between structured diabetes care routines in cardiac rehabilitation (CR) and detection and treatment of diabetes at one-year post-MI.METHODS: Center-level data was derived from the Perf
