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We conducted a randomized phase III trial to compare the efficacy and safety of two purine analogs, cladribine and fludarabine, with high-dose chlorambucil, in patients with previously untreated chronic lymphocytic leukemia (CLL). Between 1997 and 2004, 223 patients with CLL were randomly assigned to cladribine, fludarabine or chlorambucil, for six cycles of therapy with frequent health-related qu

Diffusion magnetic resonance imaging (dMRI) is a powerful non-invasive technique for probing tissuemicrostructure. While highly sensitive, conventional dMRI methods suffer from low specificity, due in part toexperimental designs that conflate multiple contrast mechanisms. This thesis aims to address these limitations bydeveloping advanced time-dependent dMRI techniques to disentangle competing sou

Molecular dynamics (MD) simulations give atomically detailed information on structure and dynamics in amphiphilic bilayer systems on timescales up to about 1 μs. The reorientational dynamics of the C-H bonds is conventionally verified by measurements of (13)C or (2)H nuclear magnetic resonance (NMR) longitudinal relaxation rates R1, which are more sensitive to motional processes with correlation t

Asbestos mining and production manufacturing infringes on the right to live free from toxic pollution. Though as this right is not yet formally codified, this thesis will make a case for its recognition and concurrently push for a global ban of this fibrous set of naturally occurring minerals that are extremely hazardous to the human body. Highlighting the grave harms of asbestos as a benchmark th

A key assumption conventionally made by flexible head-mounted eye-tracking systems is often invalid: The eye center does not remain stationary w.r.t. the eye camera due to slippage. For instance, eye-tracker slippage might happen due to head acceleration or explicit adjustments by the user. As a result, gaze estimation accuracy can be significantly reduced. In this work, we propose Grip, a novel g

Thiophene is a cyclic molecule that becomes unstable as a molecular dication. We followed the multi-step dissociation dynamics triggered by soft x-ray FEL pulses from SACLA, core-ionizing the S 2p orbital and creating parent dications by the Auger decay. The time-evolution was probed by optical laser pulsesthat reveal the survival lifetime of the parent dication and the build-up of fragmentation p

Monitoring low molecular weight heparins (LMWH's) in the perioperative period is prudent in patients at high risk of coagulative complications, especially when the patient has an epidural catheter requiring withdrawal, which is associated with the risk of spinal haematoma. The aim of this study was to evaluate the in vitro dose-responses of two different LMWH's on two different viscoelastic haemos

This work presents the results of the use of flow injection surface plasmon resonance and impedimetric affinity biosensors for detecting and enumerating total bacteria based on the binding between E. coli and Con A, immobilized on amodified gold electrode. The single analysis time for both techniques was less than 20 min. Dissociation between the immobilized Con A and the E. coli using 200 mM of g

Trellis decoding is a popular method to recover encoded information corrupted during transmission over a noisy channel. Prominent members of this class of decoding algorithms are the Viterbi algorithm, which provides maximum likelihood estimates, and the BCJR algorithm, which is a maximum a posteriori estimator commonly used in iterative decoding. In this thesis, the Viterbi algorithm is chosen si

Below you will find information regarding preparing for your arrival, collecting your keys, filling out the inspection report and other responsibilities. Arrival checklistSign the contractPlease make sure you sign your housing contract before your offer expires. It is not enough to just accept the housing offer - the contract needs to be signed as well. If you don't sign the contract before the de

https://www.luaccommodation.lu.se/researcher-accommodation/information-visiting-scholar/arrival - 2026-05-01

https://www.control.lth.se/fileadmin/control/Education/DoctorateProgram/DeepLearning/2016/dl_rnn.pdf - 2026-05-01

https://gerdahallen.com/en/it-is-now-time-to-complete-the-renovation-of-our-gym-and-make-space-for-more-free-weight-training-2/ - 2026-04-30