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The increasing spread of global pandemics such as HIV/AIDS, tuberculosis (TB) and malaria, in particular in developing countries, has forced the engagement of industrialized countries and pharmaceutical companies. Because medicines to cure these diseases are often under patent protection, they are not affordable for people in developing countries where health crises prevail. In November 2001, WTO

After hatching, bird chicks are inevitably exposed to the thermal conditions of their environment. For the first stage of development chicks are not yet fully capable of maintaining a stable body temperature. During this time, their thermal environment can cause morphological and physiological priming. The plasticity of these responses and the extent to which they persist in the long-term is not w

Oxytocin (OT) is a small neuropeptide, which is present in human plasma at extremely low endogenous levels of only a few pg/ml. It is mainly involved during labour and lactation but it has recently also been found that OT is involved in social behaviours like bonding and feeling empathy. During the last couple of years, the interest in OT has been raised and due to the matrix complexity, it is ver

CITED1 as a potential marker of treatment response in breast cancer Background Breast cancer is the most common form of cancer in women worldwide. In the clinic, breast cancer is generally divided into hormone dependent and independent form, based on whether tumor growth is driven by a certain hormone or not. Generally, patients with hormone-dependent breast cancer have a better prognosis compare

Purpose: The purpose of this exploratory qualitative research is: First, to explore what brands understand by metaverse and how they perform branding in this new context. Second, to investigate how established constructivist approaches to branding are performed within the metaverse. And finally, to define what decentralized branding is and how it is linked to a decentralized metaverse. Additionall

Delirium is a serious and common condition in the intensive care unit (ICU), which affects 30-50 % of the patients and is associated with increased mortality and morbidity in the context of long-term outcomes. No evidence-based treatment for delirium exists, and currently, delirium is mainly treated pharmacologically with haloperidol, a typical antipsychotic agent. The “Agents Intervening against

In many high-income countries, severe perinatal trauma (SPT), affecting the anal sphincter muscle complex, has been on the rise over the last decade. However, effective strategies to prevent SPT are scarce. In randomized controlled trials, only perineal warm compresses and massage have shown benefit. Other cohort studies have shown that prevention models involving several components can decrease t

Lisbeth Nilsson Summary presentation Kids Loco I am most thankful to meeting with sensai Junichi Takashio in England 2012 and getting the opportunity to visit Biwako Gakuen in 2014, and returning to Japan in 2017 and 2018. Thanks to these meetings Driving to Learn and the Assessment of Learning Powered mobility use (ALP) became known in Japan. This presentation will show what develops if an infant

ObjectiveSex differences regarding the safety and efficacy of carotid revascularization in carotid artery stenosis have been addressed in several studies with conflicting results. Moreover, women are underrepresented in clinical trials leading to limited conclusions regarding the safety and efficacy of acute stroke treatments.MethodsA systematic review and meta-analysis was performed by literature

Background: Accurate referral of boys with suspected undescended testes (UDT) is of importance to preserve fertility and reduce risk of future testicular cancer. While late referral is well studied, there is less knowledge about incorrect referrals, hence, referral of boys with normal testes. Objective: To evaluate the proportion of UDT referrals that did not lead to surgery or follow-up, and to a

BACKGROUND: Fall accidents are a major cause of mortality among the elderly and the leading cause of traumatic brain injury. After a fall, many elderly people never completely recover and need help in coping with everyday life. Due to the increasing older population in the world, injuries, disabilities, and deaths caused by falls are a growing worldwide problem. Muscle weakness leads to greatly in

Cranial radiotherapy is a known risk factor for neurocognitive impairment in survivors of childhood acute lymphoblastic leukemia (ALL). Understanding the nature of cognitive dysfunction during adulthood in ALL survivors is important as it has an impact on major life situations. Thirty-eight (21 women) ALL survivors were investigated 34 years after diagnosis. Median-age was 38 (27–46) years. All we

In the age of museomics, the ability to sequence the genetic material from old museum specimens provides an invaluable and often untapped molecular resource. The application of the latest Next-Generation sequencing (NGS) technologies to such specimens allows us to utilise the diverse biobank that is natural history museums. These approaches provide the opportunity to study both extinct or difficul

Ovarian cancer is the eighth most common female cancer worldwide and the most lethal of the gynaecologic malignancies. Around 700 women are diagnosed in Sweden per year. Due to vague symptoms most of the patients are diagnosed with late-stage epithelial ovarian cancer (EOC) and prognosis is poor, with a five-year survival of 49%. However, for early-stage EOC the prognosis is excellent. Biomarkers

Background: Optimal follow-up (FU) strategy to detect potentially curable (PC) recurrences after treatment of localised clear cell renal cell carcinoma (ccRCC) is unclear. This study retrospectively analysed a large international database to determine recurrence patterns and overall survival (OS), as part of a wider project to issue recommendations on FU protocols. Objective: To analyse associatio

Popular Abstract in Swedish Förmaksflimmer är den vanligaste rytmrubbningen i hjärtat som kräver behandling. Risken att drabbas ökar med åldern och 8% av alla åttioåringar lider av förmaksflimmer. Förmaksflimmer är i sig inte livshotande, men den förhöjda risken för proppbildning i förmaken kan leda till allvarliga komplikationer såsom stroke. Det finns olika behandlingsstrategier för förmaksflimmThis thesis deals with signal processing algorithms for analysis of the electrocardiogram (ECG) during atrial fibrillation (AF). Such analysis can be used for diagnosing patients, and for monitoring and predicting their response to various treatment. The thesis comprises an introduction and five papers describing methods for ECG-based modeling and characterization of AF. Paper I--IV deal with meth

Popular Abstract in Swedish Med snabbare och pålitligare analysresultat finns stora möjligheter till ett ökat utnyttjande av avfallsresurser för produktion av förnybar energi. Resultat från min forskning gör det möjligt att analysera råvaror för biogasproduktion med större säkerhet och med möjligheten att få upp till nio gånger snabbare resultat. Produktion av biogas har under den senaste tiden öA sustainable treatment of organic wastes, generation of renewable energy, reduction of green house gas emissions, limiting the eutrophication and closing the nutrient cycles are several environmental challenges for which anaerobic digestion may be a suitable solution. There is today a large amount of available organic waste materials that could serve as potential feedstock for biogas production.

Popular Abstract in Swedish Hemofili A är en form av blödarsjuka som beror på en medfödd defekt av äggviteämnet faktor VIII (FVIII). FVIII spelar en viktig roll för att kroppens blodlevringsförmåga (s.k. koagulation) ska fungera optimalt och med nedsatt funktion hos FVIII riskerar man att drabbas av allvarliga blödningar i framför allt leder, men även i muskler, slemhinnor (t.ex. näsblödning) och Haemophilia A (HA) is caused by defective synthesis of coagulation factor VIII(FVIII), which has serious effects on haemostasis; joints being the most common site of bleeding. The development of FVIII replacements has improved the situation for patients with haemophilia such that chronic arthropathy can be prevented, and life expectancy and the quality of life have increased. However, approximatel

Popular Abstract in Swedish Arktiska ekosystem utgör en viktig del av det globala terrestra utbytet av växthusgaser och energi med atmosfären. I ett klimat som förändras, särskilt uttalat i Arktisk, bör tänkbara framtidsprognoser av växthusgasutbytet från dessa områden övervägas noga när framtida klimat modelleras. En förutsättning för detta är detaljerade studier av nyckelprocesser som påverkar vArctic ecosystems represent an important component in the global terrestrial exchange of greenhouse gases and energy with the atmosphere. In the changing climate, which is most pronounced in the Arctic, the possible scenarios of greenhouse gas exchange response should be seriously considered in predictive climate modelling efforts. As a prerequisite for this, detailed studies of key processes affe

Popular Abstract in Swedish Talet om det mångkulturella i skolan och samhället: En analys av diskurser om det mångkulturella inom utbildning och politik åren 1973-2006 Det svenska samhället har under de senaste tre decennierna påverkats av debatter, rapporteringar och diskussioner om det mångkulturella samhället. Frågan om hur man ska handskas med ?det mångkulturella? har uppfattats och beskrivitThe debate on "multicultural issues" has had a considerable impact on society, and in Sweden, dealing with such issues has been described and defined as a major problem. The aim of the present thesis is to analyse the various contents of discourses on multicultural issues that have influenced education and policy documents during the period 1973-2006. On several occasions, the Swedish government h