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Epidermal Reactions to Injury with Implications for Innate Immunity

Popular Abstract in Swedish En värld av mikrober Vi lever i en värld full av olika bakterier och svampar, så kallade mikrober. Med tanke på artrikedomen och mängden av infektiösa mikrober vi dagligen kommer i kontakt med kan det nästan tyckas som ett smärre mirakel att vi trots allt är så friska som vi är. Detta är dock nästan helt och hållet vårt medfödda immunförsvars förtjänst. Immunförsvaret Abstract The epidermis is one of our primary interfaces towards the external milieu. Following injury, the physical barrier function of the skin is destroyed and the epidermis is left vulnerable to microbial invasion. Inducible innate immune response mechanisms exist to keep the wound site free from infection, thus allowing the wound to heal and the epidermis to re-establish its barrier function.

Methotrexate, Doxorubicin, and Cisplatin (MAP) Plus Maintenance Pegylated Interferon Alfa-2b Versus MAP Alone in Patients With Resectable High-Grade Osteosarcoma and Good Histologic Response to Preoperative MAP: First Results of the EURAMOS-1 Good Response Randomized Controlled Trial

Purpose EURAMOS-1, an international randomized controlled trial, investigated maintenance therapy with pegylated interferon alfa-2b (IFN-α-2b) in patients whose osteosarcoma showed good histologic response (good response) to induction chemotherapy. Patients and Methods At diagnosis, patients age ≤ 40 years with resectable high-grade osteosarcoma were registered. Eligibility after surgery for good

Two-Barrier Problems in Applied Probability: Algorithms and Analysis

Popular Abstract in Swedish Avhandlingen består av fem upsatser (A-E): I uppsats A undersöks tidsberoende egenskaper hos kölängdsprocessen hos ett kösystem med flera betjänter under mycket allmänna Markovska ankomstprocesser. I uppsats B undersöks en endimensionell slumpvandring som reflekteras i två barriärer. I uppsats C undersöks ruinsannolikheten i en Cramér-Lundberg-modell där utbetalningaThis thesis consists of five papers (A-E). In Paper A, we study transient properties of the queue length process in various queueing settings. We focus on computing the mean and the Laplace transform of the time required for the queue length starting at $x

Experimental and Theoretical Study of Rack Storage Fires

Popular Abstract in Swedish En experimentell och teoretisk studie kring bränder i varulager i både modell och verklig skala har genomförts. Teoretiska modeller för att beräkna flamhöjder, gas temperaturer, gas hastigheter och värmeflöde inuti spalterna mellan de lagrade varorna presenteras. Modellerna kan t ex användas för att beräkna tid till utlösning av olika sprinklers som används för att skydA theoretical and experimental study of rack storage fires and responsiveness of sprinklers is presented. Free-burn tests with non-combustible and combustible material were carried out in reduced scale with verification in large scale. Formulas for in-rack flame height, excess gas temperature, gas velocity and heat flux to storage walls are provided. The formulas include overall heat release rate,

The prognostic significance of wnt-5a expression in primary breast cancer is extended to premenopausal women.

Wnt-5a protein expression in primary tumors from unselected breast cancer patients has revealed a tumor suppressive function of the protein. However, in vitro experiments on human breast cancer cells have reported contradictory results, indicating both a tumor suppressive and promoting functions of Wnt-5a. This could be due to various functions of Wnt-5a in different subgroups of patients. The uns

A detailed analysis of sodium removal by peritoneal dialysis: comparison with predictions from the three-pore model of membrane function

Background. The development of fluid and salt retention is a potential problem for all peritoneal dialysis (PD) patients. Sodium removal by the peritoneum is predominantly determined by convective fluid loss but influenced by diffusion and sieving due to free water transport as predicted by the three-pore model (TPM). The aim of the study was to establish the effect of transport status, dwell leng

Treatment outcome in T-cell lymphoblastic lymphoma in adults - a population-based study from the Swedish Lymphoma Registry

Background. T-cell lymphoblastic lymphoma (T-LBL) is a rare neoplasm of precursor lymphoblast origin, for which there is no standard treatment for adults. Results of current treatment strategies in selected populations do exist but are largely unreported for unselected series. Here, we aimed to investigate treatment outcome in a population-based cohort. Material and methods. Patients were identifi

The Collective Dynamics of Organizational Learning: On Plurality and Multi-Social Structuring

The notion of organizations as learning entities has gained considerably in popularity over the last decade, and is now regarded an important issue both theoretically and in practice. Many organizational activities and events have been referred to as learning phenomena, and learning theory is being applied to increasingly varied and complex settings of organizational life. This divergence would su

Optimization, evaluation, and characterization of a hollow fiber supported liquid membrane for sampling and speciation of lead(II) from aqueous solutions

Hollow fiber supported liquid membrane sampling and speciation of lead(II) from aqueous solution using a selective carrier (Kelex 100) is studied. An optimization of different variables affecting permeation performance (chemical conditions of the sampling module - pH, concentration and nature of the acceptor phase, extractant concentration; membrane impregnation form; sampling time; and hollow fib

Hemodilution with dextran: Effects on blood flow and thrombus formation. An experimental study in the rabbit

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Plastikkirurgi och rekonstruktiv kirurgi syftar till att återskapa form och funktion i kroppens yttre vävnader, efter större defekter orsakade av t.ex. trafikolyckor, brännskador eller tumöroperationer. Sedan länge har man använt förflyttning av hud (hudtransplantat) och rotation eller förflyttning av större vävnadsområden med bibehålMicrovascular surgery enables free tissue flaps to cover tissue defects, e.g. after trauma and malignancies. Although major improvements in techniques have been made, problems with poor tissue circulation and thrombus formation still exist. The aim of this thesis was to investigate the effects of hemodilution on tissue blood flow and thrombus formation in an animal model. In isovolemic hemodilutio

Constructive Methods for SAGBI and SAGBI-Gröbner Bases

Popular Abstract in Swedish Avhandlingen består av en introduktion och följande artiklar: Artikel I: Using resultants for SAGBI basis verification in the univariate polynomial ring. Författare: Anna Torstensson, Victor Ufnarovski och Hans Öfverbeck. Sammanfattning: En resultant-identitet för polynom i en variabel bevisas och används för att karakterisera SAGBI-baser för underalgebror genereradeThe thesis consists of an introduction and the following four papers: Paper I: Using resultants for SAGBI basis verification in the univariate polynomial ring. Authors: Anna Torstensson, Victor Ufnarovski and Hans Öfverbeck. Abstract: A resultant-type identity for univariate polynomials is proved and used to characterise SAGBI bases of subalgebras generated by two polynomials. A new equivalent

Clinical implementation of systematic medication reconciliation and review as part of the Lund Integrated Medicines Management model - impact on all-cause emergency department revisits.

What is known and objective: Interventions involving medication reconciliation and review by clinical pharmacists can reduce drug-related problems and improve therapeutic outcomes. The objective of this study was to examine the impact of routine admission medication reconciliation and inpatient medication review on emergency department (ED) revisits after discharge. Secondary outcomes included the

Developmental studies provide new insights into the evolution of sense organs in Sabellariidae (Annelida)

BACKGROUND: Sabellarids, also known as honeycomb or sandcastle worms, when building their tubes, produce chemical signals (free fatty acids) that are responsible for larval settlement and the formation of three-dimensional aggregations. The larval palps and the dorsal hump (becoming the median organ in adults) are presumed to participate in such a substrate selection during settlement. Notably, th

Lista avtal 20150129

Blad1 Lund University Agreements Agreement number LINK Status Agreement type University Erasmus Country Erasmus City Erasmus Code City Country Agreement Contact Agreement Organisation Subject Area 295 Active Erasmus+ University of Innsbruck, Institute of Botany A INNSBRU01 A INNSBRU01 Innsbruck Austria Christina Ledje Department of Biology 0511 - 0511 Biology 294 Active Erasmus+ University of Vien

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/lista_avtal_20150129.xlsx - 2026-05-27

Facit urvalsprov191107

1 URVALSPROV MKULÄ 191107 1. En 75-årig kvinna med primär biliär cholangit (PBC) sedan många år och endast sporadiska kontakter med vården utom receptförnyelser av Ursofalk söker akut på akuten på grund av hematemes. Hennes partner beskriver en successiv avtackling med trötthet och förvirring de senaste månaderna. I lab ses ett spontant förhöjt PK på 1,9, trombocyter 85, albumin 28 men normala tra

https://www.medicin.lu.se/sites/medicin.lu.se/files/facit_urvalsprov191107.pdf - 2026-05-27

Clinical and genetic features of pediatric acute lymphoblastic leukemia in Down syndrome in the Nordic countries

Background: Children with Down syndrome (DS) have an increased risk for acute lymphoblastic leukemia (ALL). Although previous studies have shown that DS-ALL differs clinically and genetically from non-DS-ALL, much remains to be elucidated as regards genetic and prognostic factors in DS-ALL. Methods: To address clinical and genetic differences between DS-ALL and non-DS-ALL and to identify prognosti

Nya stambanan Hässleholm - Lund

Den svenska järnvägstrafiken är hårt belastad med den befintliga befolkningsmängden. Den nya Stambanan mellan Lund C - Hässleholm C som är en del av det nya järnvägsnätet upp till Stockholm, kommer inte bara att förse Sveriges befolkning med bättre kapacitet och fler resmöjligheter, utan kommer även minska restiden från dagens 4,5 H till 2,5 H (Hässleholm - Stockholm). Detta innebär inte bara bättThe swedish railway infrastructure is under significant stress even with the current population, and while the growth is seemingly suspected to increase steadily in the foreseeable future there will be a lack of capacity according to Trafikverket, if the railway doesn’t expand. The new main railway between Lund C and Hässleholm C which is a part of the new railway up to Stockholm, will not only se

Developing Guidelines for Proactive Supply Chain Risk Management - A Case Study at IKEA Category Food Logistic Services

The number of supply chain disruptions has increased over the last couple of years. The Covid-19 Pandemic, blockage of the Suez Canal and Russian invasion of Ukraine are some well-known examples of disruptions. Academia seems to have noticed the increasing disruptions and has explored proactive Supply Chain Risk Management (SCRM) as an approach to address this. Consulting firms also suggest compan

Att sälja en vara så som den är – fri från ansvar? - Närmare om förutsättningarna för en vara att anses felaktig då den sålts med förbehållet ”befintligt skick”

I denna uppsats undersöks vad det innebär att en vara säljs med ett förbehåll såsom befintligt skick, särskilt utifrån 19 § köplagen. Uppsatsen tar sikte på de rekvisit som återfinns i det första stycket 19 § köplagen, och ämnar utröna när en vara kan anses felaktig trots att den sålts med ett förbehåll så som exempelvis befintligt skick. I det första stycket i 19 § köplagen återfinns tre punkter This essay examines what it means when a product is sold in its existing condition, especially based on 19 § the sale of goods act. The essay aims at the requisites found in the first paragraph of 19 § the sale of goods act and aims to find out when a product can be considered faulty even though it was sold with a reservation such as, “as is”. In the first paragraph of 19 § the sale of goods act,

Inköpsmätning av indirekt material och tjänster - en flerfallsstudie

Syfte: Syftet med detta examensarbete är att undersöka hur mogna företagets inköpsavdelningar är och om mognadsgrad har något samband mellan hur de arbetar och mäter sin inköpsfunktion, samt att undersöka hur stora företag jobbar med indirekt inköp idag. Problembeskrivning: De olika frågorna som studien önskar besvara kan sammanfattas enligt följande: * Var befinner sig företagens mognadsgrad enlPurpose: The purpose of this master's thesis is to examine how companies work with performance measurements for purchasing of indirect materials and services and its relation to purchasing maturity. Problem formulation: These are the five research questions for this study: * How developed are the companies purchasing departments? * How are the companies working with indirect purchasing? * Wha