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Multi-echelon inventory systems with shipment consolidation : methods for exact analysis and optimization

Efforts to reduce greenhouse gas emissions, globalized markets with intense competition, and generally rising transportation costs emphasize the importance of achieving economically and environmentally sustainable distribution systems. Many international organizations predict that if no new measures are implemented, global carbon dioxide emissions from freight transport will increase to even highe

Impact of pre-treatment on the stability and leachability of three different wastes

The effect from mechanical-biological pre-treatment (MBT) of wastes in Sweden and Germany has been studied. The organic matter and biological activities were studied and compared. Other parameters such as heavy metals and nutrients were examined and related to the organic matter. The effect of low water content on degradation was investigated and the relevant legislation in the two countries was s

Hollow fiber liquid phase microextraction as a preconcentration and clean-up step after pressurized hot water extraction for the determination of non-steroidal anti-inflammatory drugs in sewage sludge

A method for the quantitative determination of non-steroidal anti-inflammatory drugs (NSAIDs) in sewage sludge was developed and validated. The target compounds were extracted using pressurized hot water extraction (PHWE) and then purified and preconcentrated by three-phase hollow fiber liquid phase microextraction (HF-LPME) followed by LC-ESI-MS analysis. The PHWE was optimized with regard to the

Församlingen i granskningssamhället

Avhandlingens empiriska syfte är att undersöka vad som händer när globala marknadsorienterade modeller för granskning och kvalitet tas i bruk i lokala församlingar. Särskild uppmärksamhet ägnas församlingarnas diakonala arbete. Undersökningen baseras på fallstudier där ett urval av församlingar och granskningsmodeller är studieobjektet. Avhandlingen har även ett teoretiskt syfte: att i samspel medThe empirical aim of the thesis is to investigate what happens when global market-oriented models for auditing and quality assessment are taken up by local parishes. Particular attention is paid to the diaconal work of the parishes. The study is based on case studies where a number of parishes and auditing models provide the object of study. The thesis also has a theoretical aim: to test, in inter

Unveiling the power of selling spare-parts as a happy-meal

Companies selling industrial machines are seeing a shift where profits are moving from new sales, towards retrieving revenue throughout the whole customer life cycle. Instead of selling new machines, the companies in the industry need to look towards what is referred to as “the aftermarket”. The aftermarket is the part of the market where spare-parts and maintenance services are sold to existing c

”Vi ses snart igen” - Svenska polisers handlingsutrymme och samverkan med socialtjänsten i LOB-ärenden

It has at times been a debate among media and legislators about the Swedish police officers dis-cretionary application and great room for interpretation when dealing with the Swedish act: the Act (1976:511) on arrest of intoxicated people, etc. (our translation) which in Swedish is short-ened: LOB. It has also been comments on the law's primary care purpose, which is strongly em-phasized in th

Mitochondrial toxicity of metformin and phenformin in human peripheral blood cells assessed by high-resolution respirometry

Popular science summary Do metformin and phenformin cause toxicity to mitochondria of human blood cells? Metformin and phenformin are anti-diabetic drugs associated with lactic acidosis as a rare side effect. This side effect is thought to be due to drug-induced mitochondrial dysfunction. In this project, the mitochondrial toxicity of metformin and phenformin was assessed in human blood cells. I

Novel Vinylpyridine Based Cationic MIP Monoliths for Enantiomer Separation in CEC

Cationic vinylpyridine based molecularly imprinted polymer monoliths were, for the first time, applied to enantiomer separation using capillary electrochromatography. In order to map the synthesis conditions under which superporous monoliths are obtained, capillary columns were prepared by an in situ polymerization technique using varying monomer and porogen compositions. Both electrolyte pH and p

The Impact of Advanced Home Care on Health-related Quality of Life Reports in the end of life from palliative care patients with cancer

ABSTRACT The aim of the present work was to compare patients with advanced cancer receiving specialized palliative home care with those receiving conventional care. A hospital-based advanced home care programme was initiated, in order to enable patients to remain at home for a longer period and to choose to die at home. The allocation to advanced home care (AHC) or conventional care (CC) was perf

Predatory Pricing Policy under EC and US Law

Predatory pricing poses a dilemma which perplexed and intrigued the competition community for many years. It is one of the most discussed topics in the area of antitrust economics, as the critical issue is to meld economic insights with sound legal rules. Despite the energy devoted to the subject by many distinguished observers from the economic and legal professions and their attempts to find pro

The Chinese automotive industry: WTO accession, problems in going global and future potential

The Chinese economy has been growing with a pace and duration that the world has never seen before. Since 1978, the country has been facing a constant economic growth for more than 30 years. One of the pillars of the economy is the automotive industry; an interesting mixture of Joint Ventures and independent companies. The competition is cut throat and has even been more intense after the China’s

Managing Positions in a Dynamic Environment - New Technology Impact on Tactel and the Telecom Industry

The Telecom industry is facing a paradigm shift, where the industry is converging with Internet technologies and the market is becoming more sophisticated. This results in more demanding customers, and the need for offering more content and services with a focus on usability for the end-users. The operators are starting to loose both their strong position and revenue in the Telecom industry, due t

Comparison between comparative tuberculin and gamma-interferon tests for the diagnosis of bovine tuberculosis in Ethiopia

A study to determine and compare the sensitivities and specificities of the comparative cervical tuberculin (CCT) and gamma-interferon (IFN-gamma) tests for the diagnosis of bovine tuberculosis was conducted on 30 zebu oxen. The results of the tests were compared with the presence of acid-fast bacilli found by bacteriological culturing and histopathological examinations. The sensitivity and specif

Neuropsychological performance differs between type 1 diabetic and normal men during insulin-induced hypoglycaemia

Cerebral function was measured with a neuropsychological test battery before, during, and after insulin-induced hypoglycaemia (blood glucose approximately 2.0 mmol l-1) in 10 male Type 1 diabetic patients (age 20-43 years, duration of diabetes 14 (2-30) years) and in 12 normal men. There were no group differences in neuropsychological results at normal glucose levels. Significant effects of hypogl

5-ALA for photodynamic photorejuvenation - Optimization of treatment regime based on normal-skin fluorescence measurements

Background and Objectives: Photodynamic therapy using 20% 5 aminolevulinic acid (5-ALA) has recently been introduced as a new tool in optical skin rejuvenation. The primary objective of this study was to optimize incubation time, the topical delivery mechanism (vehicle) and the concentration of 5-ALA by detecting the dynamic changes of normal skin after 5-ALA application. The secondary objective w

Evaluating the accuracy and precision of a two-compartment Kärger model using Monte Carlo simulations.

Specific parameters of the neuronal tissue microstructure, such as axonal diameters, membrane permeability and intracellular water fractions are assessable using diffusion MRI. These parameters are commonly estimated using analytical models, which may introduce bias in the estimated parameters due to the approximations made when deriving the models. As an alternative to using analytical models, a

Birimian crustal growth in the West African Craton : U-Pb, O and Lu-Hf isotope constraints from detrital zircon in major rivers

Combined U-Pb, O and Lu-Hf isotope analyses of detrital zircon grains from five major rivers in Ghana are used to investigate the growth and evolution of the Birimian terrane of the West African Craton. The majority of the analysed zircon yields supra-chondritic εHf values, suggesting derivation from primarily juvenile host magmas. Zircon grains from the Birim River in southwestern Ghana deviate f

A review of the stable isotope bio-geochemistry of the global silicon cycle and its associated trace elements

Silicon (Si) is the second most abundant element in the Earth’s crust and is an important nutrient in the ocean. The global Si cycle plays a critical role in regulating primary productivity and carbon cycling on the continents and in the oceans. Development of the analytical tools used to study the sources, sinks, and fluxes of the global Si cycle (e.g., elemental and stable isotope ratio data for