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Objective. To investigate whether measurements of proinsulin and/or intermediate proinsulin degradation products could be used to differentiate between autoimmune (type 1) and non-autoimmune (type 2) diabetes in young adults. Material and methods. Total proinsulin, intact proinsulin and 32,33 split proinsulin concentrations were measured in 25 patients aged 15-34 years with type 1 diabetes, as def

This study investigates the mechanisms of (de)coding modality, focusing on the interpretation of utterances containing the modals must, may, måste, and kan. The main research question posed in this study is what enables the interlocutors to interpret modal expressions so that communicative goals are achieved. To answer this general question, Coates's (1983) study on modal contexts is initially rep

Phosphatidylethanol (PEth), a direct ethanol metabolite, is detectable in blood for more than 2 weeks after sustained ethanol intake. Our aim was to assess the usefulness of PEth [comparing sensitivity, specificity and the area under the curve (AUC)] as compared with carbohydrate-deficient transferrin (CDT), gamma-glutamyl transpeptidase (GGT) and mean corpuscular volume (MCV), calculating the res

Large-eddy simulation with a finite-rate chemistry model is carried out to investigate the formation of soot and nitrogen oxides (NOx) in the dual-fuel spray combustion. Liquid n-heptane is injected into a constant volume chamber, filled with a premixed methanol–air mixture with an equivalence ratio (ϕm) of 0.3. Three dual-fuel cases are simulated under initial temperatures of 900, 950 and 1000 K.

The ability to generate and control movement is essential for human interactions and overall well-being. Neuromuscular impairment caused by neurological injuries and diseases, such as stroke or limb amputation, severely limits the ability of affected individuals to interact with the surrounding environment, necessitating advanced strategies for rehabilitation and restoration of motor function. Vol

Capturing ultrafast phenomena requires imaging techniques capable of resolving events occurring on femtosecond time scales. Traditional high-speed cameras are limited by electronic readout speeds and cannot reach the terahertz (THz) frame rates necessary to observe processes such as laser filamentation, plasma formation, or light-matter interactions in general. To overcome these limitations, this

Aims/hypothesis: Some studies find an increased risk of type 1 diabetes in children exposed to antibiotics. We investigated if exposure to antibiotics increases the risk of latent autoimmune diabetes in adults (LADA) and type 2 diabetes. Methods: We used data from a Swedish case–control study (Epidemiological Study of Risk Factors for LADA and Type 2 Diabetes [ESTRID]: LADA, n=597; type 2 diabetes

The 4MOST consortium is currently halfway through a Conceptual Design study for ESO with the aim to develop a wide-field (>3 square degree, goal >5 square degree), high-multiplex (>1500 fibres, goal 3000 fibres) spectroscopic survey facility for an ESO 4m-class telescope (VISTA). 4MOST will run permanently on the telescope to perform a 5 year public survey yielding more than 20 million spectra at

In recent years, the data science and remote sensing communities have started to align due to user-friendly programming tools, access to high-end consumer computing power, and the availability of free satellite data. In particular, publicly available data from the European Space Agency’s Sentinel missions have been used in various remote sensing applications. However, there is a lack of studies th

Objectives: Health promotion is on the global agenda. The risks targeted include smoking, hazardous alcohol consumption, nutrition and insufficient physical activity. Implementation of clinical health promotion, however, remains a major challenge. While several processes, models and frameworks for strategic implementation exist, very few have been tested in randomized designs. Testing a strategic

Governance issues surrounding technologies are profound. This is best illustrated in the context of climate change that does not only exert severe, pervasive and multifaceted impacts on the environment and on the everyday lives of people around the world, but also further aggravates the tension between law, technology and the public in a broader societal context. As a response to feckless global a

The main purpose of this thesis is to present a Cultural-Historical Activity Theory (CHAT) based analysis of the activities conducted by and with visually impaired users supported by audio-haptic technology.This thesis covers several studies conducted in two projects. The studies evaluate the use of audio-haptic technologies to support and/or mediate the activities of people with visual impairment

BackgroundLow concentrations of serum selenium (Se) and its main transporter selenoprotein P (SELENOP) are associated with a poor prognosis following breast cancer diagnosis. Recently, natural autoantibodies (aAb) with antagonistic properties to SELENOP uptake have been identified in healthy subjects, and in patients with thyroid disease. Given the potential transport disrupting properties, we hyp

Normal birth is a eustress reaction, a beneficial hedonic stress with extremely high catecholamines that protects us from intrauterine hypoxia and assists in the rapid shift to extrauterine life. Occasionally the cellular O2 requirement becomes critical and an O2 deficit in blood (hypoxemia) may evolve to a tissue deficit (hypoxia) and finally a risk of organ damage (asphyxia). An increase in H+ c

Mineral building materials suffer from weathering processes such as salt efflorescence, freeze-thaw cycling, and microbial colonization. All of these processes are linked to water (liquid and vapor) in the pore space. The degree of damage following these processes is heavily influenced by pore space properties such as porosity, pore size distribution, and pore connectivity. X-ray computed micro-to

Popular Abstract in English What is common between the science of physics and global politics? They both define power in terms of energy. Indeed, the uneven distribution of petroleum reserves has been one of the main reasons of social, political and economic problems worldwide. Even more worrying is the rapid increase in the levels of greenhouse gases in the atmosphere. This is mainly caused by ouCaldicellulosiruptor saccharolyticus is an extremely thermophilic, strictly anaerobic, Gram-positive and cellulolytic microorganism with a natural ability to produce hydrogen (H2) at nearly theoretical maximum yield, i.e. 4 mol/ mol of glucose. Due to its CO2-free combustion and high energy density, among other desirable properties, H2is touted as a fuel of the future. Biological H2 production b

BACKGROUND: The Swedish school-based vaccination programme offers HPV vaccine to girls born ≥1999 in 5-6th grade. In 2012, all counties introduced free-of-charge catch-up vaccination campaigns targeting girls born 1993-1998. Varying vaccine uptake in the catch-up group by December 2012 suggested that some implementation strategies were more successful than others. In order to inform future vaccina

AIM: To describe sociodemographic disparities in temporal trends of incidence and age distributions of first registered osteoarthritis (OA) diagnosis in southern Sweden.METHODS: We identified all Skåne residents aged 35+ who had lived in the region at any point during the period 2006-2019 with no previous OA diagnosis (ICD-10 codes M15-M19) for 8 years prior to inclusion in the study (n = 849,061)

Since I finished my PhD thesis in June 2014, I have lived a stimulating but also somewhat precarious life at Lund University. It is no secret that permanent teaching positions are hard to come by, and during the time I have been teaching as temporary staff on a number of different courses, I have started to consider what the lack of permanent positions means for the pedagogical work carried out at

https://www.sol.lu.se/media/documents/persons/MatsRoxendal/RESEBOKARE_Lucat_ansoka_om_ny_alt_ta_bort_ansokt_behorighet_anvandare.pdf - 2026-05-14