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The aim of this study was to create a scenario for a simulation model where the Swedish fire commanders could practice tactics, techniques and giving orders in a rescue operation. The object on which the fire scenario is created is an athletic centre in Lund called Gerdahallen. Both the computer model HAZARD and hand calculations have been used to construct a model of the fire in this building. Th
Cancer överkommer kroppens immunförsvar och andra tumör-bekämpande system, bland annat genom att öka eller minska uttrycket av vissa gener. Gener som är viktiga för cell-cykelprogressionen är ofta påverkade. Till exempel är genen wee1 ofta överuttryckt i cancer. wee1s funktion är att koda för ett protein som förhindrar att cellen fortsätter i cellcykeln om den har trasigt DNA. Ett förslag på canceIn this study the yeast S. pombe is used to try to find genes which can (potentially in the future) be targeted in cancer cells to stop the cells from growing. WEE1 is a kinase important for proper cell-cycle progression, as it inhibits cyclin-dependent kinases activity. It is overexpressed in many cancers and many studies are being done researching how WEE1 inhibitors can be used as a cancer trea
This thesis is trying to identify and give solutions for the problems occurring in polyurethane sport surfaces in Iraq where the climate is extremely warm and dusty. One of the most important problems (called the ‘maintenance’ problem) is that the polyurethane sport surface looks very dirty because of the dust, a couple of weeks after installation of the surface the dust particles penetrates the s
This degreework was initiated by a brief email send form the department of design science at Lund Institute of Technology, Lund University. It was an invitation from the company Reflectil Sverige AB about their interest to renew their selection of non-professional high visibility garment. The companies demand was to broaden their selection of nonprofessional high visibility garment. They wanted to
The global aviation industry is experiencing growing pressure to decarbonize, driving significant demand for Sustainable Aviation Fuel (SAF). Second-generation feedstocks that do not directly compete with food crops, such as lipid oils from insects and lignin-derived oils, are promising sources, but their high concentrations of inorganic contaminants and oxygen make them incompatible with existing
This study aimed to test and validate a dual-time-window (DTW) protocol for 6-(fluoro-18F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([18F]MK6240) dynamic PET imaging in experimental datasets acquired in human subjects. Methods: DTW protocols were tested and validated in datasets previously collected in 25 participants: 13 were cognitively normal, 10 had mild cognitive impairment, and 2
BACKGROUND: Nitrones such as 2-sulfo-phenyl-N-tert-butyl nitrone (S-PBN) are known to trap and stabilize free radicals and to reduce inflammation. Recently, S-PBN was shown to reduce infiltration of T lymphocytes and the expression of adhesion molecules on the endothelium in experimental traumatic brain injury. We hypothesized that S-PBN could reduce infiltration of T lymphocytes during cell-media
The general aim of the research programme SPEAK (Sustainable Planning andEnvironmental Assessment Knowledge, www.speakproject.se) was to generateknowledge on, and to strengthen the role of strategic environmental assessment(SEA) in planning as a measure to attain the environmental quality objectives andto promote sustainable development. The SPEAK programme had atransdisciplinary point of departur
BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015), we
In recent years, the data science and remote sensing communities have started to align due to user-friendly programming tools, access to high-end consumer computing power, and the availability of free satellite data. In particular, publicly available data from the European Space Agency’s Sentinel missions have been used in various remote sensing applications. However, there is a lack of studies th
IntroductionIn speech, there are no blank spaces to signal boundaries between words as there is in written language, but listeners can nevertheless recognise individual words rapidly. Without these blank spaces or commas, listeners have to divide up – segment – the continuous speech stream into discrete words using other means. This study aimed to investigate the tonal cues important for speech se
This work has been made as a thesis for a BSc degree in Fire Protection Engineering at Lund University. The work has been supported and funded by ESS AB, European Spallation Source, in Lund. ESS AB is a publicly held company, owned by Sweden and Denmark as host countries. These host countries, together with at least 17 other European countries, will build and establish a multidisciplinary research
Background: One of the global targets for non-communicable diseases is to halt, by 2025, the rise in the age standardised adult prevalence of diabetes at its 2010 levels. We aimed to estimate worldwide trends in diabetes, how likely it is for countries to achieve the global target, and how changes in prevalence, together with population growth and ageing, are aff ecting the number of adults with d
This thesis aims to acquire deep knowledge on turbulent premixed combustion at high Karlovitz (Ka) number conditions with the help of laser-based diagnostic measurements.Considering that ammonia (NH3), as a carbon-free energy carrier, is a promising candidate for replacing conventional fossil fuels in the future, all the investigations in this work were carried out on ammonia/air premixed flames.
We characterised patients with mantle cell lymphoma (MCL) with poor prognosis based on differences in immune infiltration. Different expressions of the tumour cell markers Cyclin D1 and sex-determining region Y-box transcription factor 11 (SOX11), and the immune markers cluster of differentiation 3 (CD3), CD4, CD8, CD25, forkhead box protein P3 (FoxP3), T-box transcription factor TBX21 (T-bet), pr
Telomere erosion has been proposed to be tightly associated with senescence, environmental stressors and life history trade-offs. How telomere dynamics vary across life stages and especially in relation to (heritable) phenotypic traits is still unclear. The tawny owl Strix aluco display a highly heritable melanin-based colour polymorphism, a grey and a brown morph, linked to several fitness traits
Large-eddy simulation with a finite-rate chemistry model is carried out to investigate the formation of soot and nitrogen oxides (NOx) in the dual-fuel spray combustion. Liquid n-heptane is injected into a constant volume chamber, filled with a premixed methanol–air mixture with an equivalence ratio (ϕm) of 0.3. Three dual-fuel cases are simulated under initial temperatures of 900, 950 and 1000 K.
Objectives: Antibodies against anti-CD74 are related to axial spondyloarthritis (axSpA). The objectives were (i) to study IgA anti-CD74 in radiographic (r)-axSpA patients in the Backbone cohort and to calculate the sensitivity and specificity of anti-CD74, (ii) to study the fluctuation of IgA anti-CD74 levels in prospectively collected samples, and (iii) to explore the relation between IgA anti-CD
Totalbudget för Lunds universitet 2023 Postadress Box 117, 221 00 Lund Telefon, 046-222 8620 E-post filip.bengtsson@eken.lu.se Webbadress www.lu.se Universitetsstyrelsen Totalbudget för Lunds universitet 2023 • Budgeterat resultat för 2023 visar ett underskott på 100 mnkr fördelat på ett underskott på 10,1 mnkr inom utbildning och ett underskott på 89,9 mnkr inom forskning. • Intäkterna förväntas
https://www.ekonomiwebben.lu.se/sites/ekonomiwebben.lu.se/files/2023-10/fullstandigt_beslut_totalbudget_2023.pdf - 2026-05-16
