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Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. GAGs are normally attached to a core protein as a part of a proteoglycan; however, GAG biosynthesis can be induced by compounds composed of a xylos
Working with relationships and making use of what we commonly call emotions are common in the health and care professions. The purpose of this paper is to explore knowledge in health and care professions – especially in situations that involve strong feelings. Is there any kind of knowledge that gets lost in the process of fitting health and care work into an evidence-based or time-efficient templ
Överlåtelsedirektivet uttrycker att överlåtarens rättigheter och skyldigheter visavi de arbetstagaren som går över till förvärvaren ska övergå automatiskt och omedelbart. Det är inte tydligt huruvida detta inkluderar de rättigheter och skyldigheter som följer av nationell rätt. Principiellt ska Rom I-förordningen tillämpas på anställningsavtal, och tillämplig lag ändras. Det ter sig som om detta The Transfer of Undertakings Directive expresses that the transferor’s rights and obligations vis-à-vis the employee that are transferred to the transferee shall be transferred automatically and immediately. It’s not clear whether this includes the rights and obligations that are based on statutory law. In principle, the Rome I Regulation is applicable with regards to employment contracts, and th
Nowadays, is becoming increasingly frequent holding events in outdoor environments, involving a large number of people, even though these spaces were not designed from a safe prospective, in the way that safety is defined today. In such events, high density conditions is an ongoing issue, as the evacuation becomes very complex, due to the space design and the interaction among the pedestrians. It
Den moderna tidens tekniska utveckling har lett till att allt större och mer omfattande skadeståndsmål anhängiggörs i domstolarna. Fler sakägare är berörda, de tvistiga frågorna i målet är allt mer tekniskt komplicerade och bevismaterialet är omfattande. Domstolarna har stundom hanterat en sådan situation genom att använda sig av pilotmålsmodellen. Modellen har ingen klar definition och användningTechnological development in modern times has led to increasingly larger and more extensive tort cases being brought before courts. The processes are difficult to handle, time-consuming and costly. The courts have occasionally handled the situation by using a model called “pilotmålsmodellen” (or “test case model”). The model has no clear definition and the field of usage is indistinct. The model i
Det pågår just nu en omställning från fossila till förnyelsebara energiresurser. Exempel på förnyelsebara resurser är sol-, vind- och vattenkraft. Problemet är att energiproduktionen är beroende av att solen skiner, vinden blåser eller att vattnet flödar. Lösningen kan vara att lagra energin i smältsalter. I det här projektet utvecklades metoder för att internt kunna studera smältsaltskorrosion avMolten salt applications are challenging from a material perspective. This degree project was carried out at Alfa Laval to give them a better understanding of the corrosion of solar salt on the standard heat exchanger material stainless steel 321. Similar tests have previously been performed externally. By developing test methods for in-house corrosion testing time and money can be saved. In thi
Cancer kan drabba vem som helst och kan ha sitt ursprung i många olika områden i kroppen. Antalet nya cancerfall ökar varje år, men vissa typer av cancer har bättre prognos än andra. Den vanligaste cancertypen i Sverige är prostatacancer och den drabbar framför allt äldre män. Prostatacancer har god prognos och det finns effektiva metoder att helt bota prostat- acancer om den behandlas i ett tidigPurpose: Recent developments in external radiotherapy and its utilization with artificial in- telligence (AI) enables advanced treatment plans for a range of different disease sites. By adapting to the anatomy of the day, target coverage can be ensured while sparing more healthy tissue. The purpose of this project was to study the feasibility and benefits of daily cone beam computed tomography (CB
The aim of this research is to understand and unpack the phenomenon of brand ambassadorship by examining the sensemaking and actualization as well as the consequences of it. The study adopts an employee-perspective on brand ambassadorship to scrutinize the phenomenon in terms of what is here referred to as ’situational’ brand ambassadorship. The employee-perspective has been often neglected in pre
Befolkningen i Sverige står inför en demografisk utveckling och en allt större andel av Sveriges befolkning kommer vara äldre. År 2018 estimerades att andelen personer äldre än 80 år kommer öka med upp till hela 50 procent i Sverige under de närmaste tio åren Det leder i sin tur till en större påfrestning på landets vård och omsorg och det kommer behövas fler äldreboenden för att möta den ökande eThe Swedish population is facing a demographic development that will result in a larger proportion of the population being older than it is today. This will lead to a greater strain on the country’s health- and elderly care systems. In 2018, it was estimated that the proportion of people older than 80 years will increase by as much as 50 % in Sweden over the next ten years. With an increased numbe
Cold attics are a common element present in the Swedish residential building stock. They are known to be prone to mould problems due to their low ventilation and are one of the main channels through which buildings lose heat. One of the strategies that can help solve cold attic problems and at the same time contribute to solving the housing crisis is their conversion into habitable spaces. This re
Begreppet barnets bästa är inte något nytt begrepp inom den svenska familjerätten. Det är ett begrepp som med tiden har mognat och blivit allt mer anpassat till barnets behov. I denna uppsats ges till en början en historisk återblick kring barnets bästa och en inblick i hur utvecklingen har sett ut i den svenska rätten. Den tar också fasta på den nuvarande lagstiftningen för barnets bästa och barnThe term the best interest of the child is not a new concept in the Swedish family law. It is a concept that has developed with time and become more and more adapted to the child's needs. In this paper is initially given a retrospective about the best interests of the child and an insight into how the development has been in the Swedish law. It also takes note of the current legislation for th
Penningtvätt har länge varit ett uppmärksammat problem, men inte förrän på senare år, särskilt efter den 11 september 2001 och terroristattackerna i USA har stora krafttag gjort att bekämpningen av problemet kommit igång. Bekämpningen och förhindrandet av penningtvätt och finansiering av terrorism är även viktigt utifrån ett större perspektiv. Om man kan strypa finanserna för kriminell verksamhet,
A powerful cartel forces customers to pay significantly more for products and eliminates competition since its participants do not need to improve their productivity or the quality of their products. Cartels have historically exercised great influence over the international economy. During the inter-war period cartels were so powerful that economists have estimated that international cartels contr
Samhället genomgick under 1900-talet stora förändringar. Välfärdsstatens socialpolitiska reformer gjorde att familjens roll förändrades – allt fler av de funktioner som tidigare var förbehållna familjen kom nu att övertas av samhället. Kvinnans ekonomiska självständighet och jämställdhet med mannen stärktes. Kvinnor blev också i allt större utsträckning verksamma på arbetsmarknaden. SkilsmässotaleThe society has experienced major changes in the 20th century. The social politics of the Swedish welfare state has impacted the family role. Important functions which were earlier carried out within the family, is now provided by the social welfare system. The economical independency of the spouses and gender equality strengthened during this period. An additional important factor for the reforma
När det föreligger ett fel i en fastighet finns det flera påföljder som står köpa-ren till buds. Den vanligaste åtgärd som en köpare vidtar i dessa fall är att begära kompensation för felet genom ett prisavdrag. Prisavdrag är en påföljd vars syfte är att återställa den avtalsbalans mellan parternas prestationer som rubbats med anledning av felet. Hur man återställer denna avtalsbalans beror på vilWhen there is a defect in a property, there are several remedies available to the buyer. The most common action a buyer takes in these cases is to request compensation for the defect through a price reduction. Price reduction is a remedy aimed at restoring the contractual balance between the parties’ performances that has been disturbed due to the defect. Depending on the type of agreement the per
Organismal abundance tends to decline with increasing body size. Metabolic theory links this size structure with energy use and productivity, postulating a size–abundance slope of −0.75 that is invariant across environments. We tested the robustness of this relationship across gradients of protist species richness (1–6 species), temperature (15°C–25°C) and time. Using replicated microcosms, we pro
En förutsättning för att ett beteende ska kriminaliseras är att det tänkta straffbudet avser ett identifierat och konkretiserat intresse som är skyddsvärt, det vill säga godtagbart. Ett godtagbart skyddsintresse kan definieras som det värde som skyddas i ett visst straffbud. Föreställningarna om skyddsintresse har systematisk betydelse för indelningen av brottstyper. Att finna arten av det intressA prerequisite for a behavior to be criminalized is that the intended criminal law provision applies to an identified and concretized interest that should be protected. An acceptable protective interest can be defined as the value protected in a particular criminal law provision. The concepts of protective interests have a systematic significance for the classification of the type of crime. Determ
Introduction: The effects of the GLP-1 analogue liraglutide on time in hypoglycaemia, time in hyperglycaemia, and time in range for type 2 diabetes patients initially treated with multiple daily insulin injections (MDI) were investigated. Variables associated with hypoglycaemia in the current population were also identified. Methods: Analyses were based on data from a previously performed double-b
IMPORTANCE The positron emission tomography (PET) tracer [18F]flortaucipir allows in vivo quantification of paired helical filament tau, a core neuropathological feature of Alzheimer disease (AD), but its diagnostic utility is unclear. OBJECTIVE To examine the discriminative accuracy of [18F]flortaucipir for AD vs non-AD neurodegenerative disorders. DESIGN, SETTING, AND PARTICIPANTS In this cross-
