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OER-Open possibilities for learning. A national initiative financed by the Internet Infrastructure Foundation .SE

Open Educational Resources (OER) are teaching, learning and research materials available on the Internet. Resources are open and free, and usually under creative commons licenses (cc). Depending on the licenses resources are allowed to be used, reused, transmitted, and also sold openly and freely. Internationally, the OER movement is very strong. In Sweden, however, the trend towards open publicat

Adjuvant systemic therapy of gastrointestinal stromal tumors The Scandinavian Sarcoma Group perspective

Gastrointestinal stromal tumors (GISTs) have a malignant potential varying from virtually no risk of recurrence (microscopic GISTs) to a high risk. Acquired secondary mutations that interfere with imatinib binding have been identified as a common mechanism for drug resistance and tumor progression in advanced GIST. Patients with advanced GIST but with a small tumor mass have the longest time to di

Attosecond Electron Wave Packet Interferences

Attosecond pulses offer a new route to produce temporally localized electron wave packets (EWPs) that can easily be tailored by altering the properties of the attosecond pulses. In this thesis we will present different experiments, supported by theory, where attosecond EWPs are created in presence of a strong infrared (IR) field. By tuning the central frequency of the attosecond pulses and/or chan

Decrease by 50% of plasma IgA tissue transglutaminase antibody concentrations within 2 months after start of gluten-free diet in children with celiac disease used as a confirming diagnostic test.

Background Histological examination of small bowel biopsies is normally the gold standard for the diagnosis of celiac disease (CD). The objective of this study was to investigate whether the rate of decreases in elevated plasma IgA tissue transglutaminase antibody (IgA-tTG) and/or IgG deamidated gliadin peptides antibody (IgG - DGP) concentrations could be used as a confirming test for CD in child

Long-term effects of early parasite exposure on song duration and singing strategy in great tits

Song is a sexually selected trait in many bird species and has been suggested to function as a signal of a male's health and parasite resistance. Here we present an experimental field study on the long-term effects of parasite exposure early in life on adult bird song. We exposed nestling great tits (Parus major) to ectoparasitic hen fleas (Ceratophyllus gallinae) and on their recruitment into the

Radioiodine Therapy of Hyperthyroidism - Simplified patient-specific absorbed dose planning

Popular Abstract in Swedish Radiojodbehandling av sköldkörteln är den vanligaste radiofarmakaterapin. För att beräkna aktiviteten 131I som krävs för att ge en viss stråldos till sköldkörteln behöver sköldkörtelns massa och den individuella biokinetiken bestämmas. Biokinetiken består vanligtvis av det individuella upptaget av jodid och den biologiska halveringstiden av jod i sköldkörteln. Den bioloRadioiodine therapy of hyperthyroidism is the most frequently performed radiopharmaceutical therapy. To calculate the activity of 131-I to be administered for giving a certain absorbed dose to the thyroid, the mass of the thyroid and the individual biokinetic data, normally in the form of uptake and biologic half-time, have to be determined. The biologic half-time is estimated from several uptake

Investigation of Momentum Correction Factor in the Swash Flow

Swash flows are commonly modeled using the nonlinear shallow water equations (NSWEs). In the derivation of the NSWEs, directly from depth-averaging the Navier-Stokes equations, a so-called momentum correction factor, β, emerges. In this study we present a numerical model of the NSWEs that includes β, which is allowed to vary in space and time, and feedback onto the flow. We apply this model to a s

Intensive motherhood and educational desires in uncertain times: Negotiating ambiguous expectations in twenty-first century Singapore

This paper explores intensive motherhood and educational desires in contemporary Singapore. Singapore’s education system is globally renowned for its high academic standards and for producing students who excel in international assessment tests and rankings. At the same time, there has been a shift of attention in education policy towards social-emotional competencies and well-being. While a top-n

Impact of Varying Velocities and Solvation Boxes on Alchemical Free-Energy Simulations

Alchemical free-energy perturbation (FEP) is an accurate and thermodynamically stringent way to estimate relative energies for the binding of small ligands to biological macromolecules. It has repeatedly been pointed out that a single simulation normally stays near the starting point in phase space and therefore underestimates the uncertainty of the results. Therefore, it is better to run an ensem

Harmonization through adjudication New trends and challenges

This chapter studies the evolution of the classic legislative concepts developed by the Court of Justice of the European Union (CJEU) in its free movement jurisprudence. The idea is to discuss the key decisions mentioned by Piet Jan Slot in his article (‘Harmonisation’) published in 1996 in European Law Review and analyse these decisions in a new light and a new context. In a nutshell, the chapter

Exploring practices for managing product returns in internet retailing

Purpose: To empirically explore and describe the process and practices of managing product returns in Internet retailing.Design/methodology/approach: A multiple case study involving twelve e-commerce firms and four logistics service providers. Using semi-structured interviews, documentation, and observations as an integrative data collection approach to gain a comprehensive managerial and operatio

Generalized Proportional Allocation Policies for Robust Control of Dynamical Flow Networks

We study a robust control problem for dynamical flow networks. In the considered framework, traffic flows along the links of a transportation network —modeled as a capacited multigraph— and queues up at the nodes, whereby control policies determine which incoming queues are to be allocated service simultaneously, within some predetermined scheduling constraints. We first prov

Local structural mechanism for phase transition and ferroelectric polarization in the mixed oxide K0.5Na0.5NbO3

(KxNa1-x)NbO3 (KNN) and its solid solutions are considered as potential alternatives to traditional Pb-based piezoelectric materials. Recent investigations indicated that the local structure in KNN is much more complex than its long-range average structure. Here, we have undertaken a systematic investigation of the temperature-dependent evolution of local and average structures of KNN5 [(KxNa1-x)N

Efficient downlink power allocation algorithms for cell-free massive mimo systems

Cell-free Massive MIMO systems consist of a large number of geographically distributed access points (APs) that serve the users by coherent joint transmission. The spectral efficiency (SE) achieved by each user depends on the power allocation: which APs that transmit to which users and with what power. In this article, we revisit the max-min and sum-SE power allocation policies, which have previou

Intranuclear HSV-1 DNA ejection induces major mechanical transformations suggesting mechanoprotection of nucleus integrity

Maintaining nuclear integrity is essential to cell survival when exposed to mechanical stress. Herpesviruses, like most DNA and some RNA viruses, put strain on the nuclear envelope as hundreds of viral DNA genomes replicate and viral capsids assemble. It remained unknown, however, how nuclear mechanics is affected at the initial stage of herpesvirus infection—immediately after viral genomes are ej

Proteomic Alterations in Follicular Fluid of Human Small Antral Follicles Collected from Polycystic Ovaries—A Pilot Study

Polycystic ovaries (PCO) contain antral follicles that arrest growing around 3–11 mm in diameter, perturbing the dominant follicle’s selection and the subsequent ovulatory process. Proteomic alterations of PCO follicular fluid (FF) (i.e., microenvironment in which the oocyte develops until ovulation) have been studied from large follicles in connection with oocyte pickup during ovarian stimulation

Impact of urbanization on per capita energy use and emissions in India

Purpose: The purpose of this study is to investigate the impacts of urbanization on per capita energy consumption and emissions in India. Design/methodology/approach: The present study analyses the effects of urbanization on energy consumption patterns by using the Stochastic Impacts by Regression on Population, Affluence and Technology in India. Time series data from the period of 1960 to 2015 ha