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In a 24-year sub-sample taken from a 42-year period of study (1950-1991), hip fracture incidence was analysed from a defined catchment area within one hospital. During this time, 8,256 hip fractures occurred in a generated risk population of 1,915,571 person-years. Crude incidence increased three-fold in women and five-fold in men. In men, the age-specific increase was twice as large as the age dr
In order to survive, individuals must be able to recognise and eliminate pathogens. The genes of the Major Histocompatibility Complex (MHC) play an essential role in this process in vertebrates as their diversity affects the repertoire of pathogens that can be recognised by the immune system. Emerging evidence suggests that birds within the parvorder Passerida possess an exceptionally high number
AIMS/HYPOTHESIS: The aim of this work was to investigate, in children newly diagnosed with type 1 diabetes: (1) the prevalence of autoantibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TGAb); and (2) the association between TPOAb, TGAb or both, with either islet autoantibodies or HLA-DQ genes. METHODS: Blood samples from 2,433 children newly diagnosed with type 1 diabetes were analys
Shrunken Pore Syndrome was recently suggested for the pathophysiologic state in patients characterized by an estimation of their glomerular filtration rate (GFR) based upon cystatin C, which is lower or equal to 60% of their estimated GFR based upon creatinine, i.e. when eGFRcystatin C ≤ 60% of eGFRcreatinine. Not only the cystatin C level, but also the levels of other low molecular mass proteins
Shrunken pore syndrome (SPS) is a condition in which estimated glomerular filtration rate (eGFR) based upon cystatin C is lower than eGFR based upon creatinine. It has been associated with increased mortality even in the presence of normal GFR in both a cardiac surgical population and a general population. No systematic studies of the variation in eGFR cystatin C /eGFR creatinine -ratio used fo
Under the influence of neo-liberal ideals such as New Public Management, the ownership, operation, and maintenance of many Critical Infrastructures have been divided among an increasing number of public as well as private actors. Limited research has investigated the role of this institutional fragmentation for shaping resilience of Critical Infrastructures, especially in relation to recovery afteUnder the influence of neo-liberal ideals such as New Public Management, the ownership, operation, and maintenance of many Critical Infrastructures have been divided among an increasing number of public as well as private actors. Limited research has investigated the role of this institutional fragmentation for shaping resilience of Critical Infrastructures, especially in relation to recovery afte
Background Recent policy in Sweden states that patients in every part of health care are to be presented with health counselling concerning living habits: tobacco, alcohol, an inactive lifestyle and eating habits. This review aims to investigate experiences and preferences of counselling about living habits from the patient’s perspective. Method A literature review of six major databases using a
Background: Lung T1 is a potential translational biomarker of lung disease. The precision and repeatability of variable flip angle (VFA) T1 mapping using modern 3D ultrashort echo time (UTE) imaging of the whole lung needs to be established before it can be used to assess response to disease and therapy. Purpose: To evaluate the feasibility of regional lung T1 quantification with VFA 3D-UTE and to
Communication interventions are commonly proposed as a way to address people’sfear and negative attitudes to build tolerance in shared landscapes between humansand large carnivores. Therefore, managing authorities sometimes respond to people’sfear of brown bears (Ursus arctos) by organizing an information meeting. This studyincreases the understanding of the information meeting to address fear of Communication interventions are commonly proposed as a way to address people's fear and negative attitudes to build tolerance in shared landscapes between humans and large carnivores. Therefore, managing authorities sometimes respond to people's fear of brown bears (Ursus arctos) by organizing an information meeting. This study increases the understanding of the information meeting to address fear
In many animals, catabolic and anabolic periods are temporally separated. Migratory birds alternate energy expenditure during flight with energy accumulation during stopover. The size of the energy stores at stopover affects the decision to resume migration and thus the temporal organization of migration. We now provide data suggesting that it is not only the size of the energy stores per se that
Patients with cardiac implantable electronic device (CIED) and Staphylococcus aureus bacteraemia (SAB) are at risk of having infective endocarditis (IE). The objectives were to describe a Swedish population-based cohort of patients with CIED and SAB, to identify risk factors, and to construct a predictive score for IE. Patients over 18 years old in the Stockholm Region identified to have SAB in th
Background: The combination of infliximab and immunosuppressant therapy is a standard management strategy for patients with Crohn's disease. Concerns regarding the implications of long-term combination therapy provided the rationale for a formal clinical trial of treatment de-escalation. Our aim was to compare the relapse rate and the time spent in remission over 2 years between patients continuin
We present an upgraded version of the mocca code for the study of dynamical evolution of globular clusters (GCs) and its first application to the study of evolution of multiple stellar populations. We explore initial conditions spanning different structural parameters for the first (FG) and second generation of stars (SG) and we analyse their effect on the binary dynamics and survival. Here, we fo
This paper investigates the FPGA resources for the implementation of in-cycle closed-loop combustion control algorithms. Closed-loop combustion control obtains feedback from fast in-cylinder pressure measurements for accurate and reliable information about the combustion progress, synchronized with the flywheel encoder. In-cycle combustion control requires accurate and fast computations for their
The smart factories that are already beginning to appear employ a completely new approach to product creation. Smart products are uniquely identifiable, know their current status and alternative routes to achieving their target state. The embedded manufacturing systems are vertically networked with business processes and horizontally connected to disperse value networks that can be managed in real
Background: After an esophageal resection, continuity is commonly restored by a gastric tube reconstruction and an intrathoracic anastomosis to the remaining proximal esophagus. Ischemia of the anastomotic region is considered to play a pivotal role in anastomotic leakage. Microdialysis (μD) is an excellent method to measure local biochemical substances and parameters in a specific organ or compar
The traditional industry of inshore commercial fisheries is in a state of transformation, which manifests itself in the fisheries management, in harbors and within the community of fishermen. With the help of discourse theory and the concept of positioning, an ethnographic material of docu ments, observations, interviews and news articles generated between 20112015 is analyzed. The aim is to exp
In this editorial, the author states that the importance of casting off blinders applies to topics and disciplines as much as to individuals. There is no disagreement in psychology that we are mostly ignorant of the various neurophysiological and cognitive substrates and limitations of our conscious experience, but there are other background processes that determine what, how, and even whether we
Purpose. Continuous minor steps of improvement in the management of breast cancer have resulted in decreased mortality rates during the last decades. The aim of this study was to compare the clinical outcome of patients with stage I breast cancer diagnosed during two time periods that differed with respect to adjuvant systemic therapy. Material and methods. The studied population consisted of all
