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The correct folding of proteins is of paramount importance for their function, and protein misfolding is believed to be the primary cause of a wide range of diseases. Protein folding has been investigated with time-averaged methods and time-resolved spectroscopy, but observing the structural dynamics of the unfolding process in real-time is challenging. Here, we demonstrate an approach to directly
As part of the Large Scale Biosphere-Atmosphere Experiment in Amazonia - Smoke, Aerosols, Clouds, Rainfall and Climate (LBA-SMOCC) campaign, detailed surface and airborne aerosol measurements were performed over the Amazon Basin during the dry to wet season from 16 September to 14 November 2002. Optical and physical properties of aerosols at the surface, and in the boundary layer (BL) and free tro
Mantle cell lymphoma (MCL) is a rare, often aggressive type of B-cell lymphoma with poor survival and no cure. Cancer and cancer treatment has a negative impact on health-related quality of life (HRQOL) both during active disease and in the long term, and improvement of HRQOL is a crucial objective of cancer therapy in older patients and no curative intent. Baseline HRQOL has in other lymphoma pop
Background: Minimally invasive radical trachelectomy has emerged as an alternative to open radical hysterectomy for patients with early-stage cervical cancer desiring future fertility. Recent data suggest worse oncologic outcomes after minimally invasive radical hysterectomy than after open radical hysterectomy in stage I cervical cancer. Objective: We aimed to compare 4.5-year disease-free surviv
Study Type - Diagnostic (exploratory cohort) Level of Evidence 2b OBJECTIVES: To assess variation of total prostate-specific antigen (tPSA), free PSA (fPSA), percent fPSA, human glandular kallikrein 2 (hK2) and intact PSA measured three times within 2 weeks. Knowledge of the variation in an individual's PSA level is important for clinical decision-making. PATIENTS AND METHODS: Study participants w
OBJECTIVES: To explore the associations between frailty and reproductive axis hormones (as an important regulatory system) in middle aged and older men. DESIGN: Cross-sectional. SETTING: The European Male Aging Study. PARTICIPANTS: Three thousand two hundred nineteen community-dwelling European men aged 40 to 79. MEASUREMENTS: Interviewer-assisted questionnaires to assess physical activity, health
The study aimed to research some social workers in the department of children and families services' view of the case “Lilla hjärtat” and the dilemmas of the case. This case, a 4-year old girl who died in the care of her parents, is well known in Sweden through the media, and the case has led to a public inquiry. The study was a case study based on seven semi-structured qualitative interviews
Swedish social services and healthcare systems have been bound by law since 2010 to collaborate when a client requires multiple interventions. This is called a Coordinated Individual Plan (CIP) to prevent clients from being overlooked by healthcare and social services. There has since been published several official reports that highlight the shortcomings of CIP. Our aim of this study was to exami
FK506-binding protein-like (FKBPL) has established roles as an anti-tumor protein, with a therapeutic peptide based on this protein, ALM201, shortly entering phase I/II clinical trials. Here, we evaluated FKBPL's prognostic ability in primary breast cancer tissue, represented on tissue microarrays (TMA) from 3277 women recruited into five independent retrospective studies, using immunohistochemist
BACKGROUND: Glutathione transferases (GST) are a group of multifunctional enzymes important in the detoxification of many electrophiles and, in addition, fatty acid hydroperoxides, thus limiting tissue damage from oxidative free radical attack. Of the four classes of GST (alpha, mu, pi, and theta), a class mu isoenzyme, GST mu, is dominantly inherited and is expressed in approximately half of the
Sammanfattning I Sverige råder ett strikt krav på konsensus när det gäller beslutanderätten vid gemensam vårdnad av barn. Detta innebär att vårdnadshavarna tvingas komma överens om princip alla frågor med undantag för den dagliga omsorgen vad gäller barnet. När vårdnadshavarna inte längre bor tillsammans efter exempel- vis en äktenskapsskillnad, finns samma samstämmighet dem emellan kanske inte lSummary In Swedish law, joint legal custody generally entails a strict requirement of con- sensus in decisions concerning the child. The basic precondition is that both parents must agree on almost all matters. An exeption from this condition can however be made in matters concerning the daily care. The housing parent has in these matters autonomy to decide. After for example a divorce, it can of
Many fire protection engineers working in the operative part of the rescue service feel that they do not have enough training for their role as Tactical leader and as On scene commander. There is a need for a tool for competence development and competence assurance. This report provides the results of a master’s thesis, with the aim to develop a prototype of such a tool. The tool is limited to the
The aim of this master thesis is to examine service meetings in high-touch businesses from the perspective of the service provider. One of the purposes is to explore on what way emotional labour appears in the funeral directors everyday labour. The other purpose is to analyze how the funeral directors provide comfort to the bereaved customers. As a framework I rely mostly on the theory of emotiona
The provision of environmental information is crucial in the effort to reach sustainability. In the last decades, it has been acknowledged that the promotion of sustainable consumption lifestyles cannot be achieved without providing individual consumers with environmental information and education. However, communicating complex environmental information to non-experts is never an easy task. The l
This master thesis project was completed in partnership with Lantmännen, known for producing Gluten Free (GF) PromOat®—a concentrated oat β glucan powder. The main aim of the thesis was to explore the properties of emulsions containing GF PromOat® oat β-glucan. It specifically focuses on the critical overlap concentration, viscosity, and stability before and after high-pressure homogenization
Den svenska regeringen presenterade år 2023 en strategi för hur vi ska ställa om till en cirkulär ekonomi. Samtidigt har ett antal nya EU-direktiv år 2024 trätt i kraft som tar sikte på regler för hur fler konsumentprodukter kan repareras för att få en förlängd livscykel. En aspekt att beakta vid strävan mot en mer cirkulär ekonomi genom nya konsumentregler för produkter är hur upphovs-rätten tillIn 2023 the Swedish government presented a strategy for how to implement a circular economy. At the same time, several EU directives have come into force during 2024 that aims to regulate how more consumer products can be repaired to prolong their life cycle. One aspect to consider when pursuing a more circular economy through reparation is how copyright to products and user manuals affects the po
Brevmall 1 Evaluation of quality in the University’s study programmes1 – a method and guidance Since 2008, Lund University is practicing systematic quality assurance of all new study programmes, within the first and second cycle, through the so-called validation process. Subsequently, as part of the 2011/2012 quality assurance work, the University has entrusted the Office of Evaluation with the ta
https://www.staff.lu.se/sites/staff.lu.se/files/methodevalqeduc2013.pdf - 2026-05-30
Bild 1 Up to now… What is geographic data: Locational – Vector, Raster Properties of geographic data: Geometry, Descriptions (attributes), Topology Visualization of geographic data: Cartography, Data characteristics (qualitative – quantitative), Graphic variables Vector data Vector structure & RDB: Computer storage of geometry and attributes, Principles & rules Relational Databases/Structured Qu
https://www.nateko.lu.se/sv/sites/nateko.lu.se.sv/files/4_5_vector_analysis_theory_kl_eng_ht17.pptx - 2026-05-30
