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Galiellalactone is a potent and specific inhibitor of STAT3 signaling which has been shown to possess growth inhibitory effects on prostate cancer cells expressing active STAT3. In this study we aimed to investigate the effect of galiellalactone on prostate cancer stem cell-like cells. We explored the expression of aldehyde dehydrogenase (ALDH) as a marker for cancer stem cell-like cells in differ
To analyse oncological and functional outcomes 12 months after treatment of very low risk prostate cancer with radical prostatectomy in men who could have been candidates for active surveillance.
BACKGROUND: The aim of this retrospective matched cohort study was to evaluate the rate of recurrence among women with delayed large flap breast reconstruction after mastectomy for breast cancer. The recurrence rate among women treated at a single hospital was compared with that in an individually matched control group of women with breast cancer who did not have reconstruction after mastectomy. M
A very high number of different types of blood cells must be generated daily through a process called haematopoiesis in order to meet the physiological requirements of the organism. All blood cells originate from a population of relatively few haematopoietic stem cells residing in the bone marrow, which give rise to specific progenitors through different lineages. Steady-state dynamics are governe
Background/Aims: Inguinal incisions are a common route of access in vascular surgery. Due to anatomical challenges and a diverse bacterial flora in this area, surgical site infections (SSI) represent a common, debilitating and sometimes life-threatening complication. The INVIPS-Trial evaluates the role of Negative Pressure Wound Therapy (NPWT) on closed inguinal incisions in elective vascular surg
Background: The transcription factor signal transducer and activator of transcription 3 (STAT3) is implicated in cancer drug resistance, metastasis, and immunosuppression and has been identified as a promising therapeutic target for new anticancer drugs. Myeloid-derived suppressor cells (MDSCs) play a major role in the suppression of antitumor immunity and STAT3 is involved in the accumulation, ge
Most common breast cancer susceptibility variants have been identified through genome-wide association studies (GWAS) of predominantly estrogen receptor (ER)-positive disease1. We conducted a GWAS using 21,468 ER-negative cases and 100,594 controls combined with 18,908 BRCA1 mutation carriers (9,414 with breast cancer), all of European origin. We identified independent associations at P < 5 × 10-8
Mixtures between choline and geranic acid (CAGE) have previously been shown to insert into lipid bilayers. This may be useful for the transdermal delivery of larger pharmaceuticals, however, little is known about the mechanism of activity. By comparing the interactions between CAGE and lipid bilayers with those of a less-active, yet closely-related analogue, choline octanoic acid (CAOT), a chemica
Kompetensförsörjningsstrategi för lärare vid naturvetenskapliga fakulteten Fakultetsstyrelsen Sida 1 av 1 FÖRSÄTTSSIDA STYRDOKUMENT Kompetensförsörjningsstrategi för lärare vid naturvetenskapliga fakulteten Typ av styrdokument: Strategi Beslutsfattare: Fakultetsstyrelsen Beslutsdatum: 2024-12-11 Diarienummer: STYR 2024/3056 Ikraftträdande: 2025-01-01 Giltighetstid: [2025-01-01 – 2027-12-31] Ersätt
Microsoft Word - Allmän studieplan_medicinsk vetenskap 2019.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: Fastställd av Forskarutbildningsnämnden de
Microsoft Word - Allmän studieplan_medicinsk vetenskap_rev 2019-12-03_klar.doc Postadress Box 117, 221 00 LUND Telefon växel 046-222 00 00 Telefax 046-222 41 70 E-post info@med.lu.se Internet http://www.med.lu.se 1 1 Forskarutbildningsnämnden ALLMÄN STUDIEPLAN FÖR UTBILDNING PÅ FORSKARNIVÅ I MEDICINSK VETENSKAP Omfattning: 240 högskolepoäng Examen: Doktorsexamen Fastställd: 2018-06-11 Reviderad: 2
CFE-Paper A5 ver 7 1Do Numbers Matter? The CFSP and the Dynamic Effects of Enlargement Do Numbers Matter? The EU’s Common Foreign and Security Policy and the Dynamic Effects of Enlargement Maria Strömvik Maria.Stromvik@svet.lu.se 2 CFE Working paper series no. 5 CENTRE FOR EUROPEAN STUDIES AT LUND UNIVERSITY: Box 52 Phone: +46 (0)46-222 88 99 SE-221 00 LUND Fax: +46 (0)46-222 40 06 Sweden Email: c
https://www.cfe.lu.se/en/sites/cfe.lu.se.en/files/2020-12/cfewp05.pdf - 2026-06-03
Rutherfords atomkärna Ernest Rutherford föddes i Nya Zeeland som son till fattiga lantbrukare. När den unge ”Ern”, som han kallades inom familjen, vid tio års ålder fick sin första fysikbok var han genast fast – men måste ändå hjälpa till med sysslorna på gården. Han var mycket studieinriktad och lyckades få universitetsstipendier. Under sin universitetstid i Nya Zeeland studerade han och uppfann
https://www.nrcf.lu.se/sites/nrcf.lu.se/files/2025-11/Rutherfords_atomkaerna.pdf - 2026-06-03
LUNDS UNIVERSITET Institutionen för Psykologi I nstitutionsstyrelsen lnstitutionsstyrelsens protokoll Närvarande Ordförande Sekreterare Ledamöter Närvaro- och yttranderätt Anmält förhinder § 1 Justeringsperson § 2 Dagordning § 3 Föregående protokoll § 4 Uppföljning beslut och ärenden a) Lägesrapport befordran till och rekrytering av professorer b) Lägesrapport förslaget att kalla professor, se IS
https://www.psy.lu.se/sites/psy.lu.se/files/is_protokoll_2019-9_191210_m_bilaga.pdf - 2026-06-03
Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor Development. 2015 Sep 15; 142(18): 3166–3177. doi: 10.1242/dev.122747: 10.1242/dev.122747 PMCID: PMC4582174 PMID: 26395143 Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor Marie
https://www.regenerative-neurobiology.lu.se/sites/regenerative-neurobiology.lu.se/files/comprehensive_analysis_.pdf - 2026-06-03
Utbildningsplan Läkarprogrammet Medicinska fakulteten MALÄP, Läkarprogrammet, 330 högskolepoäng Medical Programme, 330 credits Program utan akademiska förkunskapskrav och med slutlig examen på avancerad nivå / Second cycle degree programme not requiring previous university study Beslutsuppgifter Utbildningsplanen är fastställd av Grundutbildningsnämnden, Medicinska fakulteten 2017-12-15 med ikraft
https://www.student.med.lu.se/sites/student.med.lu.se/files/utbildningsplan_h18.pdf - 2026-06-03
Politis 1..7 DOI: 10.1126/scitranslmed.3000976 , 38ra46 (2010);2 Sci Transl Med , et al.Marios Politis Patients with Neural Transplants Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Editor's Summary The Two Faces of Fetal Grafts bioengineered or stem cells. here, is important in that it will inform future treatments with grafts that consist of cells from other sources, such a
https://www.wnc.lu.se/sites/wnc.lu.se/files/politis_et_al_sci_transl_med_2010.pdf - 2026-06-03
This report investigates how organizations deal with organizational learning during times of crisis. The aim was to contribute with a framework visualizing the most profound drivers and barriers to organizational learning during crisis management, using the covid-pandemic as a case example. A preliminary framework was developed with the literature review as a foundation to do this. An interview gu
This report examines the possibilities of decarbonising operation & maintenance vessels for a prospective floating offshore wind power park at the Utsira Nord site in Norway, through self-sufficient energy carrier production utilizing power-to-X-solutions. Possible alternative fuels are identified as compressed hydrogen, batteries, liquid hydrogen, ammonia, methanol, and biofuels, out of which
