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This thesis studied the recording methodologies of conducting unannounced evacuation drills to enhance the understanding of evacuation behaviours and performance within the Complex Muon Solenoid (CMS) cavern at CERN. The primary objective was to validate the CMS underground evacuation simulation model for planned evacuation and compare various data collection methods. An unannounced evacuation dr
Preeclampsia (PE) occurs in up to 5% of worldwide pregnancies. It is a complex disease characterised by sudden onset hypertension, and it is harmful to the mother as well as the growing baby, accounting for 40% of fetal deaths worldwide. The disease can be divided into early and late-onset PE, defined as diagnosis earlier or later than 34 weeks of gestation. Despite decades of research, the cause
We present a data-driven proof of concept model capable of reproducing expected counterparty credit exposures from market and trade data. The model has its greatest advantages in quick single-contract exposure evaluations that could be used in front office xVA solutions. The data was generated using short rates from the Hull-White One-Factor model. The best performance was obtained from a GRU neur
With the ambition to contribute to a sustainable development, this project started with aim to recycle fiber boards. The idea behind the project is to take lose fibers that come from waste product or simply just worn out fiber boards, and make them into new fiber boards. In order to achieve this, a binder is needed to hold the boards together. The aim of this thesis was to evaluate different binde
The food industry is facing challenges in responding to the climate crisis, and research highlights the potential of using Business Intelligence & Analytics for organizations sustainability efforts. The aim of this study is to holistically map through the affordance lens, what capabilities organizations in the food industry may potentially gain by using BI&A for sustainability. The study i
The purpose of the thesis is to design a new antenna system and to verify its link performance in 5G FR2 mmWave frequency for handheld devices to enable cellular communication. The main objective is to design an antenna primarily at 28GHz and 39GHz to enhance spectrum efficiency, along with improved transmission data rates, enabling new cases like Augmented Reality (AR), Virtual Reality (VR) and
Research conducted on industrial symbiosis often brings up the importance of trust and collaboration related constraints and enablers if inter-organizational efforts are to be pursued. This is also found in literature related specifically to Sweden and its agri-food sector. There are limited examples of collecting empirical evidence on trust in relation to IS and even less so with a focus on SMEs.
Spallation sources such as European Spallation Source (ESS) produces neutrons by bombarding high-energy protons onto the target wheel. To determine the location of the proton beam a Proton Beam Imaging (PBI) system will be installed. The PBI system at ESS relies on the properties of a luminescent coating that is sprayed onto the target wheel and the proton beam window. In this study, luminescent m
There is an extensive expansion of fiber infrastructure for high-speed broadband networks in Sweden, and Landskrona municipality is one of the leading examples. Owing to the superior capabilities of a fiber based network, a number of digital welfare services can be provided directly to residents and companies of the municipality. Social care is an example of a welfare service that can utilize the
Deep learning is a machine learning technique inspired by the biological nervous system. The method has been used more and more over the last decades. Within this thesis, convolutional neural networks (CNN:s) are used for Gleason classification of prostate cancer in histopathological images. The data that has been used consists of digitalized microscopic images of prostate biopsies stained with ha
Flow cytometry is a versatile tool for monitoring a microbial population at a single-cell level. Multiple parameters can be monitored based on the users’ requirements through the utilization of different dyes, biosensors etc., and the use of FCM for on-line measurements during fed-batch cultivations has the potential to be used for precise process control. This project consisted of the development
The Large Hadron Collider (LHC) at CERN is undergoing a major upgrade to prepare for the High-Luminosity LHC. It will allow for many more particle collisions to occur. Some detectors that make up the LHC experiments must be replaced to withstand the harsher conditions. In particular, the inner tracking detector (ID) of the ATLAS experiment will be replaced by the new Inner Tracker (ITk). Every co
Due to increasing global energy demands and a need to move away from non-renewable energy sources, green hydrogen is now being considered as a possible replacement for fossil-based energy sources. Especially in “hard-to-abate” sectors, such as steel and petrochemical production, and long-distance transport, where the change to renewable electricity is more difficult. Green hydrogen is produced thr
A lack of somatostatin expressing interneurons (SST INs) is known to be a factor in several neurodegenerative and neurospsychiatric diseases, such as Alzheimer disease, Parkinson’s disease and schizophrenia. Being able to efficiently obtain SST INs in vitro could enable a greater understanding and better treatment of these diseases. The development of SST INs is not yet fully understood, but it is
Background: Drug repurposing provides a cost-effective approach to address the need for breast cancer prevention and therapeutics. We aimed to identify actionable druggable targets using Mendelian randomization (MR) and then validate the candidate drugs using population-based analyses. Methods: We identified genetic instruments for 1406 actionable targets of approved non-oncological drugs based on
COVID-19 was first identified in Wuhan City in December 2019 and spread throughout Hubei Province and other parts of China. After causing significant morbidity and mortality in China, by February 2020, it had spread to numerous other countries, infecting millions of people and causing a large number of deaths across the world. The COVID-19 pandemic put a burden on almost all areas of the world inc
Influences on stratospheric aerosol during the first four months following the eruption of Kasatochi volcano (Alaska) were studied using observations at 10700 +/- 600 m altitude from the CARIBIC platform. Collected aerosol samples were analyzed for elemental constituents. Particle number concentrations were recorded in three size intervals together with ozone mixing ratios and slant column densiti
