Filetype
We have previously shown that selective heavy meromyosin (HMM) adsorption to predefined regions of nanostructured polymer resist surfaces may be used to produce a nanostructured in vitro motility assay. However, actomyosin function was of lower quality than on conventional nitrocellulose films. We have therefore studied actomyosin function on differently derivatized glass surfaces with the aim to
Appearance of dyskinesia is a common problem of long-term l-DOPA treatment in Parkinson's disease patients and represents a major limitation for the pharmacological management of the motor symptoms in advanced disease stages. We have recently demonstrated that dopamine released from serotonin neurons is responsible for l-DOPA-induced dyskinesia in 6-hydroxydopamine (6-OHDA)-lesioned rats, raising
The Ebf (O/E) family of helix-loop-helix transcription factors plays a significant role in B lymphocyte and neuronal development. The three primary members of this family, Ebf1, 2, and 3, are all expressed in adipocytes, and Ebf1 promotes adipogenesis when overexpressed in NIH 3T3 fibroblasts. Here we report that these three proteins have adipogenic potential in multiple cellular models and that p
The oscillations between glacial and interglacial climate conditions over the past three million years have been characterized by a transfer of immense amounts of water between two of its largest reservoirs on Earth - the ice sheets and the oceans. Since the latest of these oscillations, the Last Glacial Maximum (between about 30,000 and 19,000 years ago), similar to50 million cubic kilometres of
Despite the widespread dissemination of clinical practice guidelines on the prevention and treatment of cardiovascular disease (CVD), CVD causes one third of deaths worldwide and almost half of all deaths in the developed world. It is therefore likely that, although some aspects of CVD management have improved, there is still a significant shortfall between what is known about CVD prevention and w
A generally implementable method for predicting salvageability on the presenting electrocardiogram (ECG) in patients with acute myocardial infarction (AMI) would be of great clinical importance. ECG-derived Grades of Ischemia (1) have been proven useful in predicting the extent and severity of left ventricular dysfunction after anterior MI, estimating short and long-term prognosis, final infarct s
This thesis describes six empirical investigations of two techniques applied to software inspections, namely reading techniques and fault content estimation techniques. The first part of the thesis presents a series of experiments of a novel reading technique called usage-based reading. The second part investigates fault content estimation applied to the software inspection process. The estimation
This thesis has two aims: to expand the range of the field of human geography research; and to establish the importance of the geographical perspective for understanding the role of sustainability in human behaviour.
Barley is an abundant crop in Europe, which makes its straw residues an interesting cellulose source for ethanol production. Steam pretreatment of the straw followed by enzymatic hydrolysis converts the cellulose to fermentable sugars. Prior to pretreatment the material is impregnated with a catalyst, for example, H2SO4, to enhance enzymatic digestibility of the pretreated straw. Different impregn
The use of water mist for fire extinguishment has increased rapidly in recent years. The main reason is the abandonment of halon-based extinguishing systems in favour of environmentally friendlier systems. Furthermore the use of water mist systems has spread from mainly marine applications to also include the protection of buildings. The main problem in this regard is to verify the effectiveness o
In this article we address the problem of projective reconstruction of structure and motion given only image data. In particular we investigate three novel minimal combinations of points and lines over three views, and give complete solutions and reconstruction methods for two of these cases: 'four points and three lines in three views', and 'two points and six lines in three views'. We show that
The high cost of photovoltaic modules motivates the use of reflectors to increase the electricity production. The system geometry of static low-concentrating PV systems for building-integration with parabolic aluminium reflectors was optimised for maximum annual electricity production. The optical efficiency of systems with different geometries was calculated from short-circuit current measurement
This article reports on a multiblock implementation of a general three-dimensional single-block computational fluid dynamics code, which is developed in a nonorthogonal, structured, collocated finite-volume grid system, and incorporates a range of turbulence models. The multiblock implementation is essentially block-unstructured, each block having its own local coordinate system unrelated to those
Popular Abstract in Swedish Denna avhandling behandlar den process där man beräknar undervattensströmmar från ljud som reflekteras från en utsänd ljudpuls, precis som när en fladdermus bedömer omgivningen genom att lyssna på ekot. En ton skickas ut under en kort tid, och det Dopplerskift som uppkommer från rörliga föremål i vattnet kan sedan omsättas till vattenhastiget eller ström. Föremål som röThis thesis deals with the process of estimating underwater current from the backscattering signal transmitted from an ultrasonic transducer. The narrowband sinusoidal burst signal is Doppler-shifted due to the current, and this information is converted into current. The traditional mathematical model for this Doppler process is based on the assumption that the backscattering time signal is Gaussi
The COST/IWA benchmark simulation model has been available for seven years. Its primary purpose has been to create a platform for control strategy benchmarking of biological wastewater treatment processes. The fact that the benchmark has resulted in more than 100 publications, not only in Europe but also worldwide, demonstrates the interest for such a tool in the research community. In this paper,
The aim of this paper is to propose a framework for the evaluation of policy instruments designed to affect development and dissemination of new energy technologies. The evaluation approach is based on the analysis of selected outcome indicators describing the process of technical change, i.e. the development and dissemination of new energy technologies, on the basis of a socio-technical systems a
A task-oriented system structure has been developed. In normal industrial robot programming, the path is created and the process is based on the path. Here a process-focused method is proposed, where a task can be split in subtasks, one for each part of the process with similar process-characteristics. By carefully encapsulating the information needed to execute a sub-task, this component can be r
The main topic of the thesis is the connection between representation theory and special functions. We study matrix elements, coupling coefficient, and recoupling coefficients for the simplest Lie and quantum groups. We show that a large number of multivariable orthogonal and biorthogonal polynomials occurring in the literature may be obtained as coupling coefficients (generalized Clebsch-Gordan
OBJECTIVES: To explore the possibility that a paleolithic-like diet can be used in the prevention of age-related degenerative Western disease. METHODS: Literature review of African Paleolithic foods in relation to recent evidence of healthy nutrition. RESULTS AND DISCUSSION: Available evidence lends weak support in favor and little against the notion that lean meat, fish, vegetables, tubers, and f
