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Stakeholders' Opinions on a Future In-Vehicle Alcohol Detection System for Prevention of Drunk Driving

Introduction: There is a common understanding that driving under the influence of alcohol is associated with higher risk of being involved in crashes with injuries and possible fatalities as the outcome. Various countermeasures have therefore from time to time been taken by the authorities to prevent drunk driving. One of them has been the alcohol interlock. Up to now, interlocks have mainly been

Zinc is the modulator of the calcium-dependent activation of post-translationally acting thiol-enzymes in autoimmune diseases.

Post-translational modifications of proteins can generate antigenic conformations that may cause autoimmune diseases in persons with specific HLA-haplotypes. Monocytes and macrophages, attracted to an inflamed site, can release post-translationally acting enzymes, such as transglutaminases and peptidylarginine deiminases. In vivo, the activation of these enzymes is crucial for the further course o

Gymnasieskolans svenskämnen. En studie av svenskundervisningen i fyra gymnasieklasser

This dissertation explores how the school subject Swedish is constructed for various groups of upper secondary school students and how the meeting between teacher and pupils is embodied in a range of Swedish subjects. The overall aim of the study is to illustrate why the teaching of Swedish in the classes under investigation takes place the way it does, as well as to discuss possible changes on a

Aspects on Immune Complex Handling and Complement Deficiency in Relation to Pathogenic Mechanisms in Systemic Lupus Erythematosus

Popular Abstract in Swedish Komplementsystemet är en grupp proteiner som tillhör det medfödda (icke anpassningsbara) immunförsvaret hos människan. De verksamma komponenterna (ett 15-tal) förekommer i blodet, de flesta i en inaktiv form. Olika delar av komplementsystemet aktiveras av speciella molekylstrukturer, bl.a. strukturer i bakteriers cellväggar (alternativa vägen och MBL-vägen för komplemenThe autoimmune disease Systemic Lupus Erythematosus is associated with hereditary deficieny of early components from the classical pathway of complement activation, but not with deficiency of complement component C3 or of the alternative pathway components. The classical pathway is involved in elimination of pathological immune complexes from the circulation by transport via complement receptor ty

Studies on Thiol-Disulfide Oxidoreductases in Bacillus subtilis

Popular Abstract in Swedish Bacillus subtilis är en modellorganism för endosporbildande bakterier. Endosporen är ett vilostadium som kan bildas av vissa bakteriarter vid svält. Endosporer är mycket tåliga. De kan t.ex. överleva extrem värme, UV-strålning, uttorkning och farliga kemikalier utan att skadas. När tillgången på näring på nytt kan tillåta växt av bakterien, kan endosporen germinera och Bacillus subtilis is a model organism for endospore-forming gram-positive bacteria. Endospores are formed in response to nutrient starvation. They can resist harsh environments and last for long periods of time. Once nutrients again become available, the endospore can germinate and the vegetative life cycle be resumed. The outermost layers of the endospore are cortex and coat that protect the cell

Crosstalk in Wideband Wireline Systems -- Curse and Blessing

The fourth generation broadband (4GBB) concept aims for ubiquitous and high-speed data communication over the existing twisted copper pairs between the last distribution point and the customer premise equipment. Although it saves deployment cost for the last-mile communication, using the existing copper infrastructure makes the system vulnerable to crosstalk due to electro-magnetic coupling from t

Serum Neurofilament Light Chain for Prognosis of Outcome after Cardiac Arrest

Importance: Prognostication of neurologic outcome after cardiac arrest is an important but challenging aspect of patient therapy management in critical care units. Objective: To determine whether serum neurofilament light chain (NFL) levels can be used for prognostication of neurologic outcome after cardiac arrest. Design, Setting and Participants: Prospective clinical biobank study of data from t

Bringing Life to Al-karama Dam, Jordan

Jordan has one of the lowest available water supplies in the world; meanwhile Jordan has seen large increase in population and refugee’s fluxes, leading to an increase in water demand [1]. To address this unprecedented water scarcity, Jordan’s water must be used where its social and economic value is highest. Jordan must treat and reuse virtually every drop of water. It is expected to have more th

Fermentation and Cultivation Technology for Improved Ethanol Production from Lignocellulose

Popular Abstract in Swedish Arbetet i denna avhandling syftar till att förbättra etanolproduktionen från lignocellulosa. Etanol framställd från förnyelsebara råvaror har fått förnyad uppmärksamhet på grund av den växande medvetenheten om den globala uppvärmningen och farhågor för en trytande tillgång på olja. Lignocellulosa utgör en potentiell råmaterialkälla för framtida storskalig etanolproduktiThe work presented in this thesis has been aiming at improving ethanol production from lignocellulose. Ethanol from renewable resources is receiving renewed attention due to apprehensions of global warming and dwindling oil reserves. Lignocellulose constitutes a potential raw material source for large scale ethanol production. To produce ethanol from lignocellulose, the hemicellulose and cellulose

Why Women Ask for Less Salary than Men : Mediation of Stereotype Threat in Salary Negotiations

Popular Abstract in Swedish Kvinnor begär lägre lön än män i löneförhandlingar. Könsskillnader i förhandlingsprestation har nyligen förklarats som en stereotyphotseffekt. Enligt stereotype threat theory kan prestationen hos negativt stereotyperade gruppmedlemmar tillfälligt försämras i kontexter där den negativa stereotypen är framträdande. Kvinnor stereotyperas som dåliga förhandlare, jämfört medWomen ask for less salary than men in negotiations. Sex differences in negotiating performance have recently been explained as stereotype threat effects. Stereotype threat theory states that the performance of negatively stereotyped group-members can suffer in contexts where the negative stereotype is salient. Women are stereo¬typed as bad negotiators, compared to men, and previous research has sh

Strategy games; on survival and reproduction

Classical evolutionary life history concerns questions such as optimal timing of maturation, life span and number of offspring. These questions have mostly been studied theoretically under the assumption that the environment is stable and without taking into account frequency and density dependence. Life history theory is the basis for my thesis, in which I have studied the evolution of different

On the Lifecycle Management of Standards

Popular Abstract in Swedish Globala internationella standards har stort inflyttande i var nutida teknikorienterade värld. Exemplen är många: vi kan importera och exportera produkter och tjänster i de flesta andra länder, vi kan kommunicera med andra personer var de än befinner sig, vi kan även resa snabbt och effektivt. Men skapande och underhåll av internationella standarder är ingen enkel procesStandards are used everywhere in the modern world and are a fundamental part of a functioning society. But the creation and maintenance of international standards is not an easy task. In addition to the technical prerequisites that must exist to create a standard, there are also political, economic and cultural aspects that must be considered. The present thesis does not interpret all these aspec

Genetic Variation and Migration of Waders

Popular Abstract in Swedish Fåglars spektakulära flyttningresor fram och tillbaka över jordklotet har länge fascinerat forskarna, men många frågor kring fåglarnas flyttningsbeteende är ännu obesvarade. Vadare är en av de fågelgrupper som flyttar allra längst, ofta från nordliga häckningsområden uppe på den arktiska tundran till övervintringsområden på södra halvklotet. I avhandlingen används moder

On the Impact of Piston Motion and In-Cylinder Charge Composition on Energy Release, Auto Ignition and Emission Formation in Premixed Charge Internal Combustion Engines

Popular Abstract in Swedish Avhandlingen pressenterar resultat från fyra studerade områden; En undersökning av hur nya kolvrörelser (volym-vevvinkel relationer) påverkar utsläpp, effekt och verkningsgrad; En undersökning av hur kväveoxid påverkar självantändning och knack; En undersökning av hur vätgas och reformerad metanol (RMG) kan utnyttjas som bränsle, dels i vanliga tändstiftsantända (SI) moThe results presented in this thesis can be divided into four areas of investigation: Investigation of the effect of new volume-crank angle relations on engine emissions, power and efficiency; investigation of nitrogen oxides effect on auto ignition and knock in SI engines; investigation of premixed SI and HCCI engine operation with the alternative fuels hydrogen and reformed methanol gas (RMG); s

Förändring av deltagandet i produktionen : Exempel från slutmonteringsfabriker i Volvo

This dissertation focuses on the changes in the organization of the production process that occurred at Volvo Cars and Volvo Trucks in the early 1990s. The changes were directed at the established division of labor – both vertical and horizontal – between different groups of employees: managers, foremen, white and blue-collar workers. The questions posed are primarily concerned with the changes fo

Implementing clinical guidelines for co-occurring substance use and major mental disorders in Swedish forensic psychiatry : An exploratory, qualitative interview study with mental health care staff

Introduction: Patients with substance use disorders (SUD) and co-occurring mental disorders (COD) within forensic psychiatric care often suffer poor treatment outcomes and high rates of criminal recidivism, substance use, and psychiatric problems. This study aimed to describe the conditions for, and mental health care staff's experiences with, implementing integrated SUD-focused clinical guideline

On Reduction of Production Disturbances in Manufacturing Systems Based on Discrete-Event Simulation

Popular Abstract in Swedish Förbättrad effektivitet i tillverkningssystemen för att åstadkomma förbättrad output och sålunda reducera tillverkningsstörningarna är ett viktigt område. Händelsestyrd simulering kan visualisera och studera de dynamiska förloppen relaterade till total effektivitet i tillverkningssystemen. En metodik för reducering av produktionsstörningar är presenterad. Förbättringar Improved efficiency in manufacturing systems to achieve increased output and thus reduced production disturbances is a vital area. DES (Discrete-Event Simulation) can visualize and study the dynamic issues related to total efficiency in manufacturing systems. A methodology for production disturbance reduction is presented. Increased performance of manufacturing systems means not only enhanced valu

This Time It's Personal: Social Networks, Viral Politics and Identity Management

This paper deals with new forms of political mobilisation and participation in social media, such as blogs, social network sites and the likes. The main focus is on the impor-tance of social networks in providing a “media filter”, functioning as a kind of collective gatekeeper to spread news and information perceived as important, in contrast to the image of the single individual media consumer fa

Human Endogenous Retroviruses: Expression and Evolutionary Relationships

Popular Abstract in Swedish Retrovirus är en typ av virus som finns hos både människor och djur. Detta virus sprider sig genom att en virus partikel tar sig in i en cell och sedan integrerar sin virala arvsmassa in i cellens arvmassa, DNA. Retrovirusets arvsmassa är från början RNA men skrivs sedan om till DNA för att kunna integreras. I molekylärbiologins barndom trodde man att det genetiska flödThe human genome contains genetic elements which are more or less similar to infectious retroviruses. These are called human endogenous retroviruses (HERVs) and are thought to be remnants of infections in the primate lineage. Most of them have been inserted 10 to 60 million years ago but have at different time points spread in the genome via intracellular retrotransposition and make up as much as