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Annual report 2019 final 0

Interdisciplinary – The IIIEE has a genuine interdisciplinary approach synthesizing insights not only from economic theory and practice but also from natural sciences, engineering, political science, organizational, legal and behavioural studies. The IIIEE academic staff has backgrounds in diverse disciplines. Collaborative – The IIIEE education and research are performed in close collaboration wi

https://www.iiiee.lu.se/sites/iiiee.lu.se/files/annual_report_2019_final_0.pdf - 2026-05-17

Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin

Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel

Oral treatment with a vitamin D3 analogue (BXL628) has anti-inflammatory effects in rodent model of interstitial cystitis

To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc

Antibodies specific for the antigenic domain 1 of glycoprotein B (gpUL55) of human cytomegalovirus bind to different substructures

Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We

Comparison of Surface Properties of Human IgA, IgE, IgG and IgM Antibodies with Identical and Different Specificities

In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha

Purification of streptococcal protein G expressed by Escherichia coli by high performance liquid affinity chromatography using immobilized immunoglobulin G and albumin

A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz

Antibody-dependent allostery of the M1 protein

Den förrädiska antikroppen Streptokocker är en lömsk bakterie som har många olika sätt att ta sig runt vårt immunförsvar. Den kan låtsas vara en del av vår kropp genom att klä sig själv i en proteinkapsel som är väldigt likt ett mänskligt protein, bryta ned våra celler med hjälp av utsöndrade gifter och använda vårt immunförsvar mot oss genom att binda antikroppar till sig själv. En virulensfaktoThe Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands

Huvudrubrik

Huvudrubrik ‹# › Bli medlem i ett Saco-S-förbund Bli medlem i ett Saco-S-förbund 1 Bli medlem i ett Saco-S-förbund 1 Bli medlem i ett Saco-S-förbund Bli medlem i ett Sacoförbundwww.saco-s.se ‹# › Bli medlem i ett Saco-S-förbund Bli medlem i ett Saco-S-förbund • Säkerställa verksamhetens kvalitet och individuella resultat • säkerställa att SLU kan bemanna uppdrag med rätt person och rätt kompetens

https://www.saco.se/globalassets/lokala-akademikerforeningar/statlig/slu/dokument/medarbetarsamtal-vid-slu-230322.pdf - 2026-05-17

Från förening till företag - Sportslig kontra ekonomisk framgång

Syftet med uppsatsen är att undersöka vad framgång är i dagens skandinaviska elitfotbollsklubbar och vilka strategier som är användbara för att uppnå denna. Uppsatsen ämnar således belysa och klargöra de viktigaste aspekterna i en lyckad strategi inom en modern skandinavisk fotbollsklubb. Med denna kunskap har vi för avsikt att återge en bild över hur en elitfotbollsklubb strategiskt bör organiser

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Master’s Dissertation Structural Mechanics INFLUENCE OF ANNUAL RING ORIENTATION ON COMPRESSION STRENGTH PERPENDICULAR TO GRAIN IN GLULAM Report TV SM -5203 PH ILIP W A LLIN IN FLU EN C E O F A N N U A L R IN G O R IEN TA TIO N O N C O M PR ESSIO N STR EN G TH PER PEN D IC U LA R TO G R A IN IN G LU LA M PHILIP WALLIN 5203HO.indd 15203HO.indd 1 2015-06-23 15:03:362015-06-23 15:03:36 DEPARTMENT OF C

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5203.pdf - 2026-05-16

Polygenic pathways shape white matter vulnerability to Alzheimer’s disease-related pathophysiological changes

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

Jama lugar 2023 oi 230100 1695046175.41487

SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood Marija Lugar, MSc; Anne Eugster, PhD; Peter Achenbach, MD; Thekla von dem Berge, MD; Reinhard Berner, MD; Rachel E. J. Besser, MD; Kristina Casteels, MD; Helena Elding Larsson, MD; Gita Gemulla, MD; Olga Kordonouri, MD; Annett Lindner; Markus Lundgren, MD; Denise Müller, BSc; Mariusz Oltarzewski, PhD; Anne Rochtus, MD; M

https://www.gppad.lu.se/sites/gppad.lu.se/files/2024-01/jama_lugar_2023_oi_230100_1695046175.41487.pdf - 2026-05-17

Jama lugar 2023 oi 230100 1695046175.41487

SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood SARS-CoV-2 Infection and Development of Islet Autoimmunity in Early Childhood Marija Lugar, MSc; Anne Eugster, PhD; Peter Achenbach, MD; Thekla von dem Berge, MD; Reinhard Berner, MD; Rachel E. J. Besser, MD; Kristina Casteels, MD; Helena Elding Larsson, MD; Gita Gemulla, MD; Olga Kordonouri, MD; Annett Lindner; Markus L

https://www.gppad.lu.se/sites/gppad.lu.se/files/2023-10/jama_lugar_2023_oi_230100_1695046175.41487.pdf - 2026-05-17

Development-plan-research-educations-KEG-HEK

Development plan for research educations in Human Geography and Human Ecology Page 1 of 7 Faculty Board DEVELOPMENT PLAN Reg. No. STYR 2023/22 Date 2024-06-13 Development plan for research educations in Human Geography and Human Ecology Background The research education programmes in Human Geography and Human Ecology at the Department of Human Geography and the Division of Human Ecology (hencefort

https://www.sam.lu.se/en/internal/sites/sam.lu.se.en.internal/files/2024-08/development-plan-research-educations-KEG-HEK.pdf - 2026-05-17

Ana Rebordão

Sometimes it ends with a kiss Ana Rebordão creates staged environments in which she always plays the central figure, shifting between roles. Her latest piece, Sometimes it ends with a kiss, reflects on power relations within family structures. Through absurd, enigmatic performances, she evokes a sense of trauma and gives a sharp voice to silent female characters. The work shows women speaking to t

https://www.iac.lu.se/ana-rebordao - 2026-05-15

Arbetsgång/Tidsplan

Arbetsgång/Tidsplan www ceq.lth.se     Anpassa utseende Översikt English Kursutvärderingar Om LTHs kursutvärderingar Arbetsgång/Tidsplan Nyheter (+ arkiv) Info till externa representanter Kontaktinformation Mina CEQ:er/MyCEQ Dokument Kurser som utvärderas Arkiv / Färdiga kursutvärderingar Specialrapporter Examensarbeten (utvärdering) Praktikkurser (utvärdering) Institutions- sammanställning Hämta

https://www.ceq.lth.se/info/tidsplan/arkiv/ - 2026-05-16

BspK, a serine protease from the predatory bacterium Bdellovibrio bacteriovorus with utility for analysis of therapeutic antibodies

The development of therapeutic and diagnostic antibodies is a rapidly growing field of research, being the fastest expanding group of products on the pharmaceutical market, and appropriate quality controls are crucial for their application. We have identified and characterized the serine protease termed BspK (Bdellovibrio serine protease K) from Bdellovibrio bacteriovorus and here show its activit

Analysis of the molecular interplay between Streptococcus pyogenes and its human host

The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. pyogenes infections, human plasma leaks into the site of infection as a consequence of infl