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Yersinia pathogenicity is dependent on polarized translocation of effector proteins via the type III secretion system (T3SS). The tip complex situated on the needle structure of the T3SS is required for contact with the eukaryotic host membrane and is to an extent composed of pentameric LcrV. LcrV is a multifunctional protein that also acts as a regulator of the T3SS by virtue of forming a high-af
We report the discovery of two warm exoplanets orbiting the cool binary system TOI-2267, composed of the M5 (TOI-2267A) and M6 (TOI-2267B) stars, whose angular separation is 0.384 arcsec, corresponding to a projected distance of only about 8 au at 22 pc from the Solar System. To confirm the planetary nature of these objects, we combined photometry from the Transiting Exoplanet Survey Satellite (TE
Ageing in the human brain is a major risk factor for most neurodegenerative diseases. Yet the cell-type-specific molecular changes that contribute to this risk remain poorly understood. This thesis investigates cell-type-specific changes across multiple levels of molecular regulation and their roles in physiological and pathophysiological brain ageing. Using single-nucleus RNA sequencing of postmo
Context. Despite the ever-increasing number of known exoplanets, no uncontested detections have been made of their satellites, known as exomoons. Aims. The quest to find exomoons is at the forefront of exoplanetary sciences. Certain space-born instruments are thought to be suitable for this purpose. We show the progress made with the CHaracterising ExOPlanets Satellite (CHEOPS) in this field using
To plan for a sustainable transportation network, we need to understand the values connected to existing structures. In the history of car dependency and petroculture, the promise of speed is everywhere. Through a frame analysis focusing on contestation, this paper examines values connected to fossil fuel infrastructure. Specifically, the paper interrogates the plans to construct a highway on the
Adsorption onto chromium surfaces during heat treatment (65–68°C) of β-lactoglobulin A and B in phosphate buffer, pH 6.88, was investigated byin situellipsometry. Thermal unfolding andin situheat-induced aggregation under the same conditions were studied by differential scanning calorimetry and dynamic light scattering, respectively. A lag phase was observed for buildup of the thickness of th
Focusing on mounting challenges to agro-industrial capitals posed by emerging infectious diseases, this paper revisits longstanding debates in critical agrarian studies scrutinizing the role of turnover time. Analyzing Norway and Denmark's poultry industries' recent confrontations with avian influenza, and by paying close attention to the questions of temporality and disaggregating the agency of c
IntroductionPancreatic cancer has a low survival. The aim of this study was to analyze the role of tumor location on perioperative outcome and survival.MethodData on all patients with resected pancreatic ductal adenocarcinoma (PDAC) identified in the Swedish National Pancreatic and Periampullary Cancer Registry 2010-2020 were included. Tumor locations in the head, body and tail were compared. A mu
The global industrial sector is a highly polluting and greenhouse gas-emitting sector. As industries increasingly explore Artificial Intelligence (AI) to enhance operational efficiency and drive innovation, questions emerge regarding its alignment with sustainability objectives. While AI is often positioned as a key enabler of digital transformation, its sustainable integration into industrial ope
Focusing on sector-specific differences, this thesis studies the long-term effects of the Elterngeld reform of the German parental insurance on female labor market participation. With data from the Socio-Economic Panel (SOEP), the analysis is based on a cohort comparison between first-time mothers giving birth during the period 2006-2008. Due to limited data, the study focuses on the labor market
This paper aims to comprehensively examine the impact of global climate change, particularly how climate change and the natural disasters it triggers affect the insurance sector in Asia and Europe and the stock market performance of reinsurance companies in both Asia and Europe. Using an appropriate event study methodology, the study investigates the impact of two natural disasters in China and tw
Transgender individuals in Georgia face persistent stigma, violence, and limited institutional protections, yet little is known about how they cope with such hostility and what supports are available to them. Guided by Minority Stress Theory and coping research that distinguishes adaptive from maladaptive strategies, this study explored coping practices, social support, and mental health among tra
Within organizational families, listening between coworkers plays an essential role in enabling organizational success and the effective enactment of family dynamics. It allows information to circulate, collaboration to take place, and trusting relationships to develop. Yet, coworkers’ listening processes, agency and experiences in an organizational family continue to be overlooked by organization
With corporate social responsibility becoming more important to powerful companies, analyzing how the idea of sustainability circulates in a company and influences actors is key to understanding the potential and limitations of corporate social responsibility as companies’ strategic approach to sustainability. Individuals in a company act upon ideas and together form a shared reality. This thesis,
This thesis focuses on organic agriculture and alternative food networks in China, which have emerged in the midst of widespread food safety scares. Based on two months of ethnographic research with representatives and participants of alternative food networks dealing with organic food in Beijing and Shanghai, in this paper I investigate cases of ecological and community supported agriculture farm
Telia and Ericsson have executed a joint project to evaluate the Ericsson WCDMA experimental system in Stockholm, Sweden. This system has been an important tool for gaining valuable handson WCDMA experience and to support the development of the commercial 3G WCDMA system. Some results from the ongoing tests are presented in this paper.
Modeling and understanding the vortex breakdown is a key issue of modern Lean Premixed Combustors. The main difficulty of the problem is the unsteady behavior of this type of flow: Large structures resulting from vortex breakdown and the swirling shear-layers, affect directly the flame stabilization leading to heat-release fluctuations and combustion instabilities. Consequently, one needs to captu
This article contains an overview of the current proposals of converging IP-networks with PSTN. We describe Parlay and Open Service Access( OSA), two of the most promising architecture.
