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Complement is a central homeotic system of mammals and represents the first defense line of innate immunity. The human complement system is aimed to maintain homeostasis by recognizing and removing damaged or modified self material, as well as infectious foreign microbes. However, pathogenic microbes also control and escape the host complement and immune attack. The increasing resistance of microb
Järnvägen och dess moder industrialismen omformade Sverige från bondeland till industriland. Genom en förändring över endast ett 10-tal år ersattes de knaggliga vägarna och ett förlegat skjutsväsende med ett kommunikationsmedel som alla kunde resa och transportera varor med. Större delen av riket förvandlades på många vis av det nya kommunikationssättet. Även små bondbyar i Skåne blev i högsta gra
The aim of this thesis is to examine the current VAT treatment of public bodies in the EU, as defined by the rules of the VAT Directive. This study will examine and evaluate the current problems in interpretation of Art.13 of the VAT Directive and related rules and assess in specific whether the Court’s interposition has been successful in dealing with problems arising from it, or whether more fun
Hur kan man utforma det pianistiska lärandet hos pianoelever på kommunala musik- och kulturskolan? Frågan ligger centralt för denna uppsats med syftet att undersöka pianopedagogers syn på nödvändiga enheter för att uppnå balansen mellan musikaliskt uttryck och pianistiskt hantverk. I undersökningen framkommer pianopedagogernas grundtankar och strategier för ett helhetsutvecklande pianospel hos eleTitle: The pianistic learning at the Swedish Municipal School of Music and Culture – seeking balance between musical expression and piano technique. How is it possible to design the learning of piano to piano students at the Swedish municipal school of music and culture? This question is central for this paper with the purpose to study piano pedagogues’ thoughts on requisite components for achievi
Flera undersökningar har visat att arbetsminnet spelar en stor roll vid problemlösning, språkförståelse och långtidsinlärning. Eftersom den mesta forskningen hittills har gjorts på barn var vårt syfte att testa unga vuxna, vilket här innebär gymnasieelever i år 2 och 3. Testpersonerna var från 17:4 till 20:1 år. Vi ville få en inblick i hur unga vuxna kommer ihåg nya ord, som de hört i en kontext,
The overrepresentation of women in informal, insecure, low paid and precarious employments is well-documented. The purpose of this research study is to explore the livelihoods of formal, semi-formal and informal female food and beverage vendors in Dar es Salaam, Tanzania. The research questions centre on why the livelihood strategy of food or beverage vending is undertaken, what livelihood constra
Understanding and effectively managing Technical Debt (TD) remains a vital challenge in software engineering. While many studies on code-level TD have been published, few illustrate the business impact of low-quality source code. In this study, we combine two publicly available datasets to study the association between code quality on the one hand, and defect count and implementation time on the o
The anesthetic drug propofol is commonly used to control hypnotic depth (suppression of awareness) in patients undergoing surgery or intensive care. In addition to manual titration, a model-based open-loop feed-forward strategy called target-controlled infusion (TCI) has attained some clinical popularity. Research on closed-loop control, with awareness estimates derived from an electroencephalogra
Linear quadratic (LQ) control optimizes a quadratic cost function while following a linear model. It is commercially available in the process industry but often not labeled as such and infrequently used. Froth flotation is a process in the minerals industry that extracts precious metals from a slurry of finely ground rock in consecutive tanks called cells. Flotation cells are often arranged in two
Acquired angioedema due to C1-inhibitor (C1INH) deficiency (AAE) is caused by secondary C1INH deficiency leading to bradykinin-mediated angioedema episodes. AAE typically presents in adulthood and is associated with B cell lymphoproliferation. Anti-C1INH autoantibodies (antiC1INHAbs) are detectable in a subset of AAE cases and considered a hallmark of the disease. When free antiC1INHAbs and malign
Background: Little attention has been given to the risk of cardiovascular and psychiatric comorbidities during the clinical evaluation of a suspected hematological malignancy.Methods: Based on Skåne Healthcare Register, we performed a population-based cohort study of 1,527,449 individuals residing during 2005-2014 in Skåne, Sweden. We calculated the incidence rate ratios (IRRs) of cardiovascular d
Checkpoint blockade therapies have changed the clinical management of metastatic melanoma patients considerably, showing survival benefits. Despite the clinical success, not all patients respond to treatment or they develop resistance. Although there are several treatment predictive biomarkers, understanding therapy resistance and the mechanisms of tumor immune evasion is crucial to increase the f
A key challenge in X-ray crystallography is to find a good point on the crystal on which to center the beam because the crystal takes radiation damage after a number of shots which significantly distort the measurements. Therefore, the beam needs to be aimed manually by an operator, which results in significant additional effort and time.This paper presents an approach toward automating the beam a
Programmable Logic Controllers (PLCs) play an important role for integration of hardware and software in industrial robot cells. In this paper we propose a semantic grounding of the Sequential Function Charts (SFC) notation for specification of PLC programs. Our semantic grounding is expressed in the OWL semantic language and forms part of our semantic robot framework, called KIF (Knowledge Integr
A measurement of the ZZ production cross section in the ℓ−ℓ+ℓ′ −ℓ′ + and ℓ−ℓ+νν¯ channels (ℓ = e, μ) in proton-proton collisions at s=8TeV at the Large Hadron Collider at CERN, using data corresponding to an integrated luminosity of 20.3 fb−1 collected by the ATLAS experiment in 2012 is presented. The fiducial cross sections for ZZ → ℓ−ℓ+ℓ′ −ℓ′ + and ZZ→ ℓ−ℓ+νν¯ are measured in selected phase-spac
Background: Although transposition of the great arteries (TGA) accounts for less than 5% of congenital heart disease, the clinical course is often dramatic with need for early diagnosis and careful preoperative care as well as advanced surgical correction and postoperative support. Since 1993, Lund is one of the two tertiary referral centers for pediatric cardiac surgery in Sweden, with nearly 400
EU:s gemensamma jordbrukspolitik handlar i allt mindre utsträckning om produktion av jordbruksprodukter och allt mer om att utveckla landsbygden samt att föra pengar till jordbruket för att stödja jordbrukets inkomster. Stora pengar satsas också i projekt för att uppmuntra företagande och skapa sysselsättning på landsbygden, såväl av gemensamma EU-medel som från den svenska budgeten. Åtgärderna sa
