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An amino-terminal region of a, chain of type IV collagen noncollagenous domain [alpha(3)(IV)NC1] that induces experimental autoimmune glomerulortephritis (EAG) in rats has been identified. Only recombinant antigens that contain a nine-amino acid (AA) span of alpha(3)(IV)NC1, consistent with a T cell epitope, could induce EAG. It was hypothesized that synthetic peptides of this region should induce

The aim was to examine tissue expression of Ku protein in lower lip salivary gland (LSG) biopsies from cases of primary Sjogren's syndrome (SS) and from normal subjects. Methods: immunohistochemistry was used with antibodies to Ku70/86 and also Ki67, PCNA and p53. In addition, the Klenow method was applied in order to detect evidence of apoptosis. Sections of hyperplastic tonsil served as addition

In osteoarthritis (OA), cartilage and bone fragments have been described within the synovial tissue which are surrounded by synovial cells (i.e. detritus synovitis). These cells appear to attach actively to the cartilage and bone fragments. In rheumatoid arthritis (RA), on the other hand, synovial fibroblasts (SF) have also been shown to be localized at sites of invasion into cartilage and bone an

Some of the compounds used for density gradient separation of blood cells have high osmolarities at the concentrations needed to create the required specific densities. Several mixed media use a combination of hyperosmolar shrinkage and red cell aggregation to improve cell separation. Due to the characteristics of Percoll density gradient medium the density and osmolarity of the gradient can be co

Genetic segregation analysis between NOD and C57BL strains have been used to identify loci associated with autoimmune disease. Only two loci (Cia2 and Cia9) had earlier been found to control development of arthritis, whereas none of the previously identified diabetes loci was of significance for arthritis. We have now made a high-powered analysis of a backcross of NOD genes on to the B10.Q strain

The emergence of post-genomic approaches that couple chromatin immunoprecipitation (ChIP) assays to high-throughput technique has greatly advanced our ability to investigate epigenetic features associated with normal cell development and disease. Nevertheless, these techniques exhibit some limitations. Firstly, standard protocols usually require millions of cells, thus limiting their application t

Recently, we reported that DNA associated with inverse hexagonal (H(II)) lyotropic liquid crystal phases of the lipid 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) was actively transcribed by T7 RNA polymerase. (1) Our findings suggested that key components of the transcription process, probably the T7 RNA polymerase and the DNA, remained associated with the monolithic H(II) phase throughou

The orbit of a planet is surrounded by a chaotic zone wherein nearby particles' orbits are chaotic and unstable. It was shown by Wisdom that the chaos is driven by the overlapping of mean motion resonances which occurs within a distance (δa/a)chaos≈ 1.3μ^2/7 of the planet's orbit. However, the width of mean motion resonances grows with the particles' eccentricity, which will increase the width of

This paper studies the effects of stochastic time delays on automatic control systems which uses communication networks. We assume a linear process to be controlled and known delay probability distributions.The contribution of this paper is to extend the theory in(Nilsson 1998) to delays that may be longer than one sample period.Using a quadratic cost we find the optimal full-state-information con

The database of photographic meteor orbits of the IAU Meteor Data Centerin Lund has gradually been updated. The version 2001, which has beenprepared for distribution and which will be released soon, containscomplete orbital and geophysical data on 4581 meteors (equinox J2000.0).A new meteor identification code consisting of the publication serialnumber, the author or station code and number of the

This chapter examines the relationship between individual and organizational identity in PSFs and the significant but tenuous nature of elite identity in this context. The authors identify four main identity-related issues for management control in PSFs: autonomy/conformity tensions, the client conundrum, ambiguity saturation, and intangibility. They explore three main modes of identity-focused co

The thickening effect of a hydrophobically modified polymer in an O/W microemulsion is investigated. The hydrophobically modified polymer is a triblock copolymer, alkyl end-capped poly(ethylene glycol) and the microemulsion is based on a non-ionic surfactant, pentaethylene oxide dodecyl ether (C₁₂E₅) and decane. The rheological properties vary strongly with microemulsion drop

Popular Abstract in Swedish Denna avhandling handlar om arbetarförfattaren Ivar Lo-Johanssons modernitet, sådan den kommer till uttryck i de sk. statarromanerna: Godnatt, jord (1933), Bara en mor (1939) och Traktorn (1943). Först undersöks hur modernisering och modernitet skildras i romanerna och därefter hur författaren förhåller sig till den litterära riktning som kommit att symbolisera den esteThis dissertation examines the modernity of the Swedish proletarian author Ivar Lo-Johansson (1901-1990), as manifested in the so-called 'statare' novels: Godnatt, jord (Breaking Free, 1933), Bara en mor (Only a Mother, 1939), and Traktorn (1943). The dissertation examines, on the one hand, modernisation and modernity as the topoi of these novels, and on the other, how the author relates to the li