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This study provides a comprehensive evaluation of eight high spatial resolution gridded precipitation products in Adige Basin located in Italy within 45–47.1°N. The Adige Basin is characterized by a complex topography, and independent ground data are available from a network of 101 rain gauges during 2000–2010. The eight products include the Version 7 TRMM (Tropical Rainfall Measuring Mission) Mul

Investigations mapped the region(s) on the light chain of high molecular weight kininogen (HK) that participates in cell binding. Sequential and overlapping peptides of domain 5 (D5(H)) were synthesized to determine its cell binding site(s). Three peptides from non-overlapping regions on D5(H) were found to inhibit biotin-HK binding to endothelial cells. Peptides GKE19 and HNL21 weakly inhibited b

BACKGROUND: Patients with septic shock may undergo extensive physiological alterations that can alter antibiotic pharmacokinetics. OBJECTIVES: To describe the population pharmacokinetics of ciprofloxacin in septic shock and to define recommendations for effective ciprofloxacin dosing in these patients. METHODS: Adult patients with septic shock treated with ciprofloxacin were eligible for inclusion

The globular clusters of large spiral galaxies can be divided into two populations: one that formed in situ and one that comprises clusters tidally stripped away from other galaxies. In this paper, we investigate the contribution to the outer globular cluster population in the M31 galaxy through donation of clusters from dwarf galaxies. We test this numerically by comparing the contribution of glo

The influence of wind is only occasionally accounted for in fire safety engineering, still the effect of wind on, for example, the performance of a smoke management system can be large. A simple analytical method to account for the effect of wind on mass flow through horizontal openings for natural ventilation is compared to results from CFD simulations in this paper. It is seen that the correspon

HAMLET is a protein-lipid complex derived from human milk that was first described for its tumoricidal activity. Later studies showed that HAMLET also has direct bactericidal activity against select species of bacteria, with highest activity against Streptococcus pneumoniae Additionally, HAMLET in combination with various antimicrobial agents can make a broader range of antibiotic-resistant bacter

Non-healing wounds cause hundreds of thousands of deaths every year, and result in large costs for society. A key reason for this is the prevalence of challenging bacterial infections, which may dramatically hinder wound healing. With resistance development among bacteria against antibiotics, this situation has deteriorated during the last couple of decades, pointing to an urgent need for new woun

Observations of binaries containing pairs of neutron stars using the upcoming space-based gravitational wave observatory, LISA, have the potential to improve our understanding of neutron star physics and binary evolution. In this work, we assess the effect of changing the model of the Milky Way’s kinematics and star formation history on predictions of the population of double neutron stars that wi

This work investigates the black hole (BH) population of globular clusters (GCs) in Milky Way- and Andromeda-like galaxies. We combine the population synthesis code MASinGa and the MOCCA-Survey Database I to infer the properties of GCs harbouring a stellar-mass BH subsystem (BHS), an intermediate-mass BH (IMBH), or neither of those. We find that the typical number of GCs with a BHS, an IMBH, or

Stars ejected from the Galactic Center can be used to place important constraints on the Milky Way potential. We have used Hills stars to constrain models for the Galactic potential, demonstrating that meaningful constraint can be obtained if we have samples of around 50 nearby Hills stars.

This chapter focuses on the personal experiences of collaborations based on academic–practitioner interactions, which are not always as straightforward as presented in commonplace transdisciplinary theory. By using autoethnographic methodology, this chapter provides some of the most important insights from past and ongoing work from a major sustainability project that uses the ‘Research Forum’ (RF

Adaptation is becoming increasingly significant for public policy and practice in dealing with climate change-related risks and achieving sustainable development. Consequently, the exploration of different ways of assisting successful adaptation has brought under scrutiny the different lifestyles of communities all around the world. Most frameworks adopted to understand adaptation among societies

The article analyses recent public initiatives to memorialise the establishment of India and Pakistan as postcolonial states in terms of violent partitioning rather than as a successful act of independence from British imperialism. The twin focal points of the article are the Partition Museum in Amritsar and the online 1947 Partition Archive. Both of these subscribe to and further the view that di

Background and purpose — Despite the good results after total hip arthroplasty (THA), new implants are continuously being developed to improve durability. The Echo Bi-Metric (EBM) THA stem is the successor to the Bi-Metric (BM) THA stem. The EBM stem includes many of the features of the BM stem, but minor changes in the design might improve the clinical performance. We compared the migration behav

With the broader industrial application of Additive Manufacturing (AM), designers are facing new challenges in conceptual design for AM. To better understand the problematic, the authors organised a design workshop with six experts in AM. The paper presents the results of the conducted design workshop and discusses the current and future trends in research on the conceptual design for AM.