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CD1d-restricted natural killer T (NKT) cells belong to the innate-like lymphocytes which respond rapidly to stress and infectious challenge. We have studied murine CD1d-restricted NKT cells in the early immune response to virulent Salmonella enterica serovar Typhimurium after oral infection. In the liver and spleen, neutrophil and macrophage numbers had increased several-fold by day 5 post-infecti

Clin Microbiol InfectAbstract Propionibacterium acnes is a common and probably underestimated cause of delayed joint prosthesis infection. Bacterial biofilm formation is central in the pathogenesis of infections related to foreign material, and P. acnes has been shown to form biofilm both in vitro and in vivo. Here, biofilm formation by 93 P. acnes isolates, either from invasive infections (n = 45

In the absence of irradiation or other cytoreductive conditioning, endogenous hematopoietic stem cells (HSCs) are thought to fill the unique niches within the bone marrow that allow maintenance of full hematopoietic potential and thus prevent productive engraftment of transplanted donor HSCs. By transplantation of purified exogenous HSCs into unconditioned congenic histocompatible strains of mice,

Aims: Gestational diabetes mellitus affects approximately 7% of all pregnant women. Some of these women develop autoantibodies that are generally characteristic of Type 1 diabetes. Autoantibodies targeting glutamic acid decarboxylase and tyrosine phosphatase-like protein are the most frequently reported. A recently identified autoantigen in Type 1 diabetes is zinc transporter 8. Some reports sugg

PURPOSE: The early loss of a parent is a tragedy and a serious life event. This study investigated grief resolution and morbidity in cancer-bereaved teenagers 6 to 9 years after the loss of a parent to cancer. METHODS: In a nationwide population-based study of 622 of 851 (73 %) youths who as teenagers 6 to 9 years earlier had lost a parent to cancer, we explored the magnitude of unresolved grief a

Complement evasion by various mechanisms is important for microbial virulence and survival in the host. One strategy used by some pathogenic bacteria is to bind the complement inhibitor of the classical pathway, C4b-binding protein (C4BP). In this study, we have identified a novel interaction between nontypeable Haemophilus influenzae (NTHi) and C4BP, whereas the majority of the typeable H. influe

Functioning of the immune system requires the coordinated expression and action of many genes and proteins. With the emergence of high-throughput technologies, a great amount of molecular data is available for the genes and proteins of the immune system. However, these data are scattered into several databases and literature and therefore integration is needed.

In this work, we present a built-in filter method to enhance the isolation level between closely packed MIMO antennas. The built-in filter is composed of several slits etched on the ground of the antenna structure. The number and length of slits depend on both the resonance frequency and the structure of the MIMO antenna system. To illustrate its usefulness, two designs of compact planar four-port

An exploratory study on the prosodic signaling of ‘confirmation’ in Swedish is presented. Pairs of subjects read short dialogs, constructed around selected target words, in a conversational style. A falling utterance intonation was found on the target word, and the signaling of word prosody (lexical pitch accent) appeared to be, to a certain degree, optional.

The purpose of this paper is to examine current practices of load factor utilisation of road transport. An interview study of five shippers and two transport providers were conducted. The research shows that transport providers seem to work efficiently with operational practices to improve the load factor, but the load factor seems not to be highly prioritised when it comes to strategic decisions.

Supreme Audit Institutions (SAIs) constitute important democratic institutions, providing citizens with an independent analysis on how the Governmental Offices and the central public administration function. This paper reports on findings from a survey, submitted to all performance auditors at the Swedish SAI, on 3 May, 2011. The response rate was 70 per cent (65 out of 93 respondents). The survey

I detta konferensbidrag beskriver jag ett exempel på hur IKT (Informations- och kommunikationsteknik) kan användas i litteraturundervisning på gymnasiet i Sverige på ett sätt som gör det möjligt för eleverna att bli mer aktiva producenter av kunskap i en flexibel inlärningsmiljö samtidigt som man främjar en globaliserad litteratursyn, särskilt vad gäller fransk litteratur, som går bortom nationensIn this paper I describe an example of how ICT (Information and communication technologies) can be used in teaching literature at upper secondary level in Sweden in a way that lets the pupils become more active producers of knowledge in a flexible learning environment and promotes a globalized view of literature, especially of French literature, which goes beyond the nation’s borders.

Context: Dopamine agonists are the treatment of choice for prolactinomas and symptomatic idiopathic hyperprolactinemia. However, the optimal treatment strategy and treatment duration is not clear in all details. Objective: The aim of the study was to assess the effect of dopamine agonist withdrawal in patients with idiopathic hyperprolactinemia and prolactinomas. Data Sources: PubMed, the Cochrane