Filetype
Experimental investigations on the kinetics of wastewater treatment processes in biofilms were performed in a laboratory reactor. Parallel with the kinetic experiments, the influence of the biofilm kinetics on the biofilm structure was studied at macroscopic and microscopic levels. The close interrelationship between biofilm kinetics and structural changes caused by the kinetics is illustrated by
BACKGROUND: Copper and zinc are essential micronutrients and cofactors of many enzymatic reactions that may be involved in liver-cancer development. We aimed to assess pre-diagnostic circulating levels of copper, zinc and their ratio (Cu/Zn) in relation to hepatocellular carcinoma (HCC), intrahepatic bile duct (IHBD) and gall bladder and biliary tract (GBTC) cancers.METHODS: A nested case-control
Presents theory, algorithms and validation results for system identification of continuous-time state-space models from finite input-output sample sequences. The algorithms developed are methods of subspace model identification and stochastic realization adapted to the continuous-time context. The resulting model can be decomposed into an input-output model and a stochastic innovations model. Usin
Cancer can be regarded as an invasive organ that exhibits unique plasticity provided by coordinated, cancer cell-stromal cell communication in the tumour microenvironment. Typical stress factors in the tumour niche, such as hypoxia and acidosis, are major drivers and modulators of these events. Recent findings reveal an important role of extracellular vesicles and lipoproteins in cancer cell adapt
Current immune-based therapies signify a major advancement in cancer therapy; yet, they are not effective in the majority of patients. Physically based local destruction techniques have been shown to induce immunologic effects and are increasingly used in order to improve the outcome of immunotherapies. The various local destruction methods have different modes of action and there is considerable
Based on the results of an on-going monitoring program of 1612 MHz OH masers in OH/IR stars, we determined a lifetime encompassing late AGB and early post-AGB evolution of at least 4500 years. Fading of the OH masers observed with the Nançay Radio Telescope is detected in several post-AGB OH/IR stars on timescales of decades, while AllWISE/NEOWISE light curves taken almost in parallel show diverse
Syftet med studien var att undersöka om patienter som erhåller specialiserad palliativ hemsjukvård (SPH) får bättre palliativ vård, med färre besök på akutmottagning och vårddagar på sjukhus samt i högre utsträckning kan dö i sitt eget hem jämfört med de patienter som inte ansluts till SPH. Vi ville även undersöka om SPH är kostnadsbesparande.Genom retrospektiv journalgenomgång inkluderades de 150
Breathlessness that persists despite treatment for the underlying conditions is debilitating. Identifying this discrete entity as a clinical syndrome should raise awareness amongst patients, clinicians, service providers, researchers and research funders.Using the Delphi method, questions and statements were generated via expert group consultations and one-to-one interviews (n=17). These were subs
A reduction in the number of postoperative bed days for patients who underwent appendectomy led to a study of changes in hospital costs of appendectomies for the years 1955, and 1965, and 1975. No significant changes were found in the total hospital costs. However, the postoperative costs decreased by 36 percent from 1955 to 1975 due to a decrease in the mean duration of hospital stay. During the
Vacant commercial facilities are an increasing concern in many developed countries. Despitethe low occupancy rates in existing facilities, new commercial facilities that betteraccommodate the needs of modern end-users are constantly developed. In addition to financialconcerns, under-utilized spaces are a great environmental burden, as buildings account forapproximately one third of the global ener
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we h
Diabetes is a highly heterogeneous condition; yet, it is diagnosed by measuring a single blood-borne metabolite, glucose, irrespective of aetiology. Although pragmatically helpful, disease classification can become complex and limit advances in research and medical care. Here, we describe diabetes heterogeneity, highlighting recent approaches that could facilitate management by integrating three d
Most stars form in a clustered environment. Both single and binary stars will sometimes encounter planetary systems in such crowded environments. Encounter rates for binaries may be larger than for single stars, even for binary fractions as low as 10-20 per cent. In this work, we investigate scatterings between a Sun-Jupiter pair and both binary and single stars as in young clusters.We first perfo
BACKGROUND: The melanoma-specific survival (MSS) is heterogenous between stages and is highly dependent on the T stage for primary localized disease. New systemic therapies for metastatic cutaneous melanoma (CM) have been introduced since 2012 in Sweden.OBJECTIVES: To analyse the incidence and MSS time trends between 1990 and 2020 in Sweden.METHODS: Nationwide, population-based, and prospectively
Jus cogens norms and obligations erga omnes are concepts within international law that are often used to reinforce legal claims. This thesis aims to assess to what extent invoking these concepts, along with their reinforcing capabilities, is justified in specific cases. In order to achieve this, the thesis first gives an overview of the theoretical debate surrounding the concepts of jus cogens no
PURPOSE: The purpose of this research project is to further advance theory on management of product development by providing insights on customer orientations. The study contributes to the literature by bringing in Actor-Network Theory (ANT) as a new perspective to theorize the process of translations between customer orientation and engineering orientation within product development. RELEVANCE:
This thesis focuses on the presence and significance of silence in the poetic work The Psalms of Struggle and Liberation (1964), by the Nicaraguan liberation theologian Ernesto Cardenal, in which the biblical psaltery constitutes the base for a contextual interpretation. This study aims to prove the hypothesis that the white spaces in the psalms, created by the application of free verse, are possi
