Search results

Abstract is not available

Abstract is not available

Beyond indexicality in the semiotics of photography.

Antibody-based microarrays are among the new, rapidly emerging technologies within the field of proteomics that has the potential to evolve into a key proteomic research tool, providing novel means to perform early diagnostics, identify biomarkers and gain insights into disease biology. The aim of this thesis, based on five original papers, was to develop antibody microarrays based on human recom

This study investigates the relationship between prosody and information/discourse structure in spon- taneous spoken folk tales in the tonal Mon-Khmer language Northern Kammu, a language that behaves as a typical phrase language where available boun- dary tones are enhanced to mark information struc- turing. Topic is always placed before Comment by syntactic movement if necessary. There is a proso

Popular Abstract in Swedish Varför skulle det vara mer europeiskt att rösta ja till Euron än vad det är att rösta nej? Varför går det inte att vara både populist och ?god europé? på samma gång? Vad skiljer en illegal invandrare från en vanlig turist? På vilka sätt avviker Europa från andra föreställda gemenskaper som exempelvis nationen? Avhandlingen ?bringing europe down to earth? (ung. ta ner euWhy is it considered more European to vote in the affirmative of the Euro than it is to vote against it? Why is not possible to be a populist and a ?Good European? at the same time? What makes an illegal immigrant different from a tourist? These questions all concern the limits of what it means to be, act and think as Europeans in Europe. In the political process of bringing the nations and people

The thermal elimination reaction that appears in some polycarbonates has been studied by density functional theory (DFT) and ab initio methods of different levels. This work has been focused in the elimination process of ethyl formate, as a good model of this kind of reaction. Different minima and the transition state have been found to characterize the thermal elimination reaction, and the activa

We describe a novel method for determining weak association constants of oligomeric protein complexes formed transiently under equilibrium conditions. This type of equilibrium process is recognized as being biologically important, but generally hard to study. Heteronuclear spin relaxation rates measured at multiple protein concentrations are analyzed using relaxation rates predicted from hydrodyna

Binding properties of staphylococcal protein A (SpA) to different human immunoglobulins have been investigated. In this analysis, intact SpA as well as SpA-derived fragments containing one to five IgG-binding domains of different compositions, were used. The affinity binding constants of the different proteins to human polyclonal IgG, IgA, IgM and F(ab')2-fragments as well as their binding capacit

In both collagen-induced arthritis (CIA) and rheumatoid arthritis, T cells recognize a galactosylated peptide from type II collagen (CII). In this study, we demonstrate that the CII259-273 peptide, galactosylated at lysine 264, in complex with Aq molecules prevented development of CIA in mice and ameliorated chronic relapsing disease. In contrast, nonglycosylated CII259-273/Aq complexes had no suc

Radiolabelled monoclonal IgM rheumatoid factors, four from patients with type II essential cryoglobulinaemia and one originating from a patient with rheumatoid arthritis, were tested for binding to group A, B, C and G streptococci and Escherichia coli. Two of the preparations exhibited different binding patterns for the streptococci, whereas the remaining three were not reactive. The binding of on

A 12-year-old girl with multifocal skeletal sclerosis has been investigated. She was BCG vaccinated at birth and developed regional lymphadenitis in her left groin at two months of age. She was healthy until approximately 10 years of age, after which deficient height and weight gain occurred. BCG-itis was diagnosed in skeleton lesions. No evidence of immunodeficiency was found in the patient. Afte

In addition to acting as a physical barrier against microorganisms, the skin produces antimicrobial peptides and proteins. After wounding, growth factors are produced to stimulate the regeneration of tissue. The growth factor response ceases after regeneration of the tissue, when the physical barrier protecting against microbial infections is re-established. We found that the growth factors import