Search results

Promoter region sequences of human and mouse Igk-V genes were aligned and found to be conserved for about 200-300 base pairs (bp) within subgroups/families. No promoter similarity was found between IGKV promoters from different human subgroups. Related mouse Igk-V gene families were conserved in the promoter region but no similarity was evident when promoters from unrelated Igk-V gene families wer

A novel Ets protein was isolated by yeast one-hybrid screening of a cDNA library made from lipopolysaccharide-stimulated mouse splenic B cells, using the SP6 κ promoter κY element as a bait. The novel Ets protein was most closely related to PU.1 and Spi-B within the DNA binding Ets domain and was therefore named Spi-C. However, Spi-C may represent a novel subgroup within the Ets protein family, as

I artikeln presenterar forskarna Tillsammans-projektet, som syftar till att förbättra socialt stöd genom samverkan mellan civilsamhället och vården. Projektet bygger på community connector-modellen, där en samhällskontakt agerar som mellanhand för att koppla patienter till stöttande resurser. Modellen, som utvecklats genom workshops, strävar efter att skapa ett mer omfattande stöd utanför vården, I artikeln presenterar forskarna Tillsammans-projektet, som syftar till att förbättra socialt stöd genom samverkan mellan civilsamhället och vården. Projektet bygger på community connector-modellen, där en samhällskontakt agerar som mellanhand för att koppla patienter till stöttande resurser. Modellen, som utvecklats genom samskapande workshops, strävar efter att skapa ett mer omfattande stöd utan

Eosinophils are increasingly recognized as adaptable immune cells that exhibit diverse phenotypes and effector functions across different tissues and disease states. While they can induce pathology through degranulation and cytotoxic mediator release, eosinophils also fulfill regulatory and tissue repair roles. Advances in single-cell and spatial technologies have begun to reveal how microenvironm

I denna uppsats undersöks hur EU-arbetsrättens olika arbetstagarbegrepp definieras, vilken räckvidd de har samt hur dessa begrepp kan komma att utvecklas i framtiden. Arbetstagarbegreppen i både primärrätten och sekundärrätten undersöks. Undersökningen genomförs med den rättsdogmatiska metoden och den EU-rättsliga metoden. Artikel 45 FEUF var den första bestämmelsen med ett arbetstagarbegrepp i This thesis examines how the various concepts of ‘worker’ in EU labour law are defined, what their scopes are, and how these concepts may change in the future. The concepts of ‘worker’ in both primary and secondary law are examined. The examination is carried out using the legal dogmatic method and the EU legal method. Article 45 TFEU was the first regulation in the EU to contain a concept of ‘wo

Fine-needle aspiration cytology (FNAC) has been widely used as a tool to obtain specimens for the morphological diagnosis of numerous lesions in a variety of locations for more than 80 years. In many clinical situations, FNAC can render a definitive diagnosis either from aspiration smears alone using well-defined cytological criteria or from smears combined with clinical data, radiological finding

The overall aim of this article is to contribute to a research-based understanding of the increasing invisibility of web search engines in society and to discussions about the potential impact of this invisibility. It examines how search engine use and online search activities are represented in national and regional reports on internet habits and experience published by public foundations and pol

The chapter identifies several themes that are potentially significant in future research on Gen Z and sustainable tourism consumption. The need for cross-generational and cross-cultural research is identified, especially in a longitudinal context. It is also noted that the majority of research is undertaken in the developed world and the authors highlight the need for research in less developed c

It is often said that we live in a consumer society. This does not just mean that we buy things regularly but also that consumption is an integral part of our daily lives. We have learned to think of ourselves as consumers, rather than citizens, in a variety of situations. Against this backdrop, retail organisations hold a strategically important position, not least because of the space they occup

Debates around age effects in L2 learning have mostly centred around the domains of phonology, morphosyntax, and lexis. In this chapter, we expand the scope to conceptual and cognitive restructuring, much in line with Long’s (1990, 2013) discussion of the limits of age effects. Drawing on an extensive review of the extant literature, the current chapter examines the role that age of L2 acquisition

Kan framtidens shoppingupplevelse redan ha varit här? Ja mycket av det som av både upplevelse- och hållbarhetsskäl anses tillhöra framtidens konsumtion dominerade butikslokalerna i svenska städer för hundra år sedan. Det såldes livsmedel i lösvikt, man behövde handla dagligen eftersom ingen hade kylskåp hemma och det fanns många verkstäder och skräddare där man beställde precis det man behövde (ocThis chapter is a contemplation on the future experiences of local high streets based on analysing the past and present of one such local street, Södergatan in Helsingborg, Sweden. This street was established in the mid-nineteenth century, in an emerging working-class district, Söder, whose initial residents lived in crowded conditions. Without any modern technologies for storing food, or any cars

Aggressive pituitary tumors (APT) and pituitary carcinomas (PC) are heterogeneous with regard to clinical presentation, proliferative markers, clinical course and response to therapy. Half of them show an aggressive course only many years after the first apparently benign presentation. APT and PC share several properties, but Ki67 index ≥10% and extensive p53 expression are more prevalent in PCs.

Lundquist and Seedorff [1] demonstrated the presence of a zymogen in human seminal fluid, that could be activated into an active enzyme by acidification to pH 2. As the enzyme was purified, it became evident that it was in fact equivalent to the minor gastric enzyme originally named as progastricsin (EC 3.4.23.3) [2–6].This report provides a short review on the similarities and differences between

Human monoclonal antibodies specific for human cytomegalovirus (CMV) antigens have been established using peripheral blood lymphocytes from a seropositive donor. Immortalization of antigen-specific B cells was achieved by Epstein-Barr virus transformation followed by somatic cell fusion of antigen-specific lymphoblastoid cells. Four clones producing high-affinity antibodies (0.2-7 × 109 M-1) speci

What are we subjected to when presented with stories about art's past in the context of classrooms or collections? In order to prepare students for a profession in the humanities or in the field of artistic production and reception at large, art history courses in higher education are obliged to provide them with an understanding for the collection of texts, debates or works of art that are consid

Controllable doping in semiconductor nanowires is essential for development of optoelectronic devices. Despite great progress, a fundamental challenge remains in controlling the uniformity of doping, particularly in the presence of relatively high levels of geometrical inhomogeneity in bottom-up growth. A relatively high doping level of 1E18 cm-3 corresponds to just ~1000 activated dopants in a 2µ