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Organizational core values: Goals or Corporate bullshit? A study of leadership and values

Purpose : to gain knowledge on how managers experience organizational core values, and to explore how the managers look upon the significance of such values in relation to their leadership. Theoretical framework : organisational culture (Schein) and action theory (Argyris & Schön). Regarding values, social influence and theories on motivation, studies by Rokeach , Sheldon and Elliot. Theory

LL-37 and Double-Stranded RNA Synergistically Upregulate Bronchial Epithelial TLR3 Involving Enhanced Import of Double-Stranded RNA and Downstream TLR3 Signaling

The human host defense peptide LL-37 influences double-stranded RNA signaling, but this process is not well understood. Here, we investigate synergistic actions of LL-37 and synthetic double-stranded RNA (poly I:C) on toll-like receptor 3 (TLR3) expression and signaling, and examine underlying mechanisms. In bronchial epithelial BEAS-2B cells, LL-37 potentiated poly I:C-induced TLR3 mRNA and prote

Targeting MYC induces lipid droplet accumulation by upregulation of HILPDA in clear cell renal cell carcinoma

Metabolic reprogramming is critical during clear cell renal cell carcinoma (ccRCC) tumorigenesis, manifested by accumulation of lipid droplets (LDs), organelles that have emerged as new hallmarks of cancer. Yet, regulation of their biogenesis is still poorly understood. Here, we demonstrate that MYC inhibition in ccRCC cells lacking the von Hippel Lindau (VHL) gene leads to increased triglyceride

Gut-associated lymphoid tissue: a microbiota-driven hub of B cell immunity

The diverse gut microbiota, which is associated with mucosal health and general wellbeing, maintains gut-associated lymphoid tissues (GALT) in a chronically activated state, including sustainment of germinal centers in a context of high antigenic load. This influences the rules for B cell engagement with antigen and the potential consequences. Recent data have highlighted differences between GALT

‘Thou Art a Scholar, Speak to it..’ - on Spaces of Speech : A Script

This article argues, based on the work of Bakhtin and de Certeau, that there is no aesthetics without politics and that all academic discourse and practices are enacted through aesthetic forms with inherently political and ethical effects. The article is written in a script-form with indications on how to perform it, acting out or ‘performing’ in a direct way rather than adding to the arguments al

Landskrona: The Industrial City

This chapter describes the long-term social, economic, demographic, and political development of Landskrona, a mid-sized industrial city in southern Sweden. Around 1910, the population was about 15,000 and the demographic structure of the city was in line with other emerging industrial cities in Sweden. Industrial activity expanded, with some shorter periods of crisis, until the late 1960s. In mos

Economic Inequality and Social Mobility

This chapter analyzes the long-term development of income inequality and social mobility. During the twentieth century Landskrona experienced a dramatic socioeconomic transformation that shaped economic inequality and social mobility. There were three main phases in the development of socioeconomic disparities, which reflect development at the national level. The first phase (1905–1930) saw high a

Language Norms : What and where are they?

The notion of a language norm is far from clear. Lacking a conclusive explication, one may wonder what language studies are actually studying. Is it the experience of speakers? Is it their brains? Is it their behavior? Is it the product of expert intuitions? Even within linguistics the views seem scattered on this point, and no consensus has been reached on what the object of study in linguistics