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Inter-laboratory comparison of channelized hotelling observer computation

Purpose: The task-based assessment of image quality using model observers is increasingly used for the assessment of different imaging modalities. However, the performance computation of model observers needs standardization as well as a well-established trust in its implementation methodology and uncertainty estimation. The purpose of this work was to determine the degree of equivalence of the ch

Moth pheromone genetics and evolution

Argues that there is no reason to dismiss species recognition as a possible cause of evolutionary change in moth sex pheromones. Selection for species recognition cannot explain all of the diversity in sex pheromones and the data supporting this contention are weak, but the alternative causes suggested, invoking mate choice between conspecifics as the mechanism of sexual selection, has no empirica

Disorders of GABA, glycine, serine, and proline

Only for three of the known defects in the metabolism of the amino acidsGABA, glycine, serine, and proline has a more-or-less efficient treatment been reported: the GABA catabolic defect, succinic semialdehyde dehydrogenase deficiency (vigabatrin, causing substrate depletion by inhibition of GABA transaminase); the glycine catabolic defect, nonketotic hyperglycinemia (diet combined with benzoate a

Becoming ‘Unstuck’ Among Positionalities, Terms and Disciplines via Conversation (With Myself) : Exploring Potentials for Affective Reflexivity in Critical Intersex Studies

This chapter highlights the importance of collective conversations regarding how to navigate the complexity of positions, roles, stakes, interests and feelings that most researchers experience. The author explores a conversational format as a way of writing about affective reflexivity. The chapter departs in a PhD project focusing on the lived experiences of variations of sex characteristics, in o

Modals as a problem for MT

The paper demonstrates the problem of translating modal verbs and phrases and shows how some of these problems can be overcome by choosing semantic representations which look like representations of passive verbs. These semantic representations suit alternative ways of expressing modality by e.g. passive constructions, adverbs and impersonal constructions in the target language. Various restructur

Roles of Heparin-Binding Protein in Bacterial Infections.

Infectious diseases remain a major health problem, where sepsis and other severe infectious diseases are common causes of morbidity and mortality. The importance of early and appropriate treatment of sepsis and severe bacterial infections has been underlined by the successes of measures like the Surviving Sepsis Campaign, among others. Thus, there is a need for clinical and laboratory tools to ide

C4b-binding protein: The good, the bad and the deadly. Novel functions of an old friend.

C4b-binding protein (C4BP) is best known as a potent soluble inhibitor of the classical and lectin pathways of the complement system. This large 500kDa multimeric plasma glycoprotein is expressed mainly in the liver but also in lung and pancreas. It consists of several identical 75kDa α-chains and often also one 40kDa β-chain, both of which are mainly composed of complement control protein (CCP) d

IgG glycan hydrolysis by a bacterial enzyme as a therapy against autoimmune conditions.

EndoS from Streptococcus pyogenes efficiently hydrolyzes the functionally important and conserved N-linked glycan of IgG in human blood. Repeated i.v. administration of EndoS in rabbits completely hydrolyzes the glycans of the whole IgG pool, despite the generation of anti-EndoS antibodies. EndoS administration had no apparent effects on the health of the animals. EndoS hydrolysis of the IgG glyca

Värnplikten återaktiveras - En kvalitativ fallstudie på reaktiveringen av värnplikten

In 2017 the Swedish government takes the decision that conscription will be reactivated after eight years of sleep. Major system changes like this need time to find their path so they are able to produce. Therefore, several questions are raised ahead of the reactivation of the conscription. This study answers to the question why the conscription was taken back in service. The answer and driving fo

Article 34 SCA - An Obligation to Request an Advisory Opinion of the EFTA Court?

This thesis examines the question of whether Iceland, Liechtenstein and Norway are under an obligation to refer questions on the interpretation of EEA law to the EFTA Court (the Court). These countries enjoy access to the EU’s internal market through the EEA Agreement. Article 34 of the Surveillance and Court Agreement, concluded between the EEA/EFTA States, establishes an advisory opinion procedu

Strengths and Weaknesses of Applying Lean Startup Methodology: Case Study of a Solar Startup in Kenya

The aim of this exploratory research has been to examine the lean startup methodology process and foster a better way of applying this method in the global south. This is done by assessing the method’s application process of a solar startup targeting the Kenyan market - the strengths and weaknesses the company encountered during the process, measures taken by the company to overcome those weakness