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Immunomodulation - a disease-modifying avenue for treatment of Huntington's disease?

This Editorial highlights a study published in the current issue of Journal of Neurochemistry by Dobson et al. (), investigating whether the immunomodulatory agent, laquinimod exerts an immunomodulatory effect on isolated Huntington´s disease monocytes. In Huntington´s disease (HD) a central immune activation is mirrored in the periphery by a low-grade immune response and monocytes isolated from H

Proteoglycans of joint cartilage. Structure, function, turnover and role as markers of joint disease

Joint cartilage consists of cells embedded in a matrix of fibrous collagen within a concentrated water-proteoglycan gel. The integrity of this matrix is crucial for the biomechanical properties of the joint cartilage. The different components of the matrix are synthesized and degraded by the cartilage cells, a process regulated by the amount of mechanical stress applied to the chondrocytes as well

Article 34 SCA - An Obligation to Request an Advisory Opinion of the EFTA Court?

This thesis examines the question of whether Iceland, Liechtenstein and Norway are under an obligation to refer questions on the interpretation of EEA law to the EFTA Court (the Court). These countries enjoy access to the EU’s internal market through the EEA Agreement. Article 34 of the Surveillance and Court Agreement, concluded between the EEA/EFTA States, establishes an advisory opinion procedu

Strengths and Weaknesses of Applying Lean Startup Methodology: Case Study of a Solar Startup in Kenya

The aim of this exploratory research has been to examine the lean startup methodology process and foster a better way of applying this method in the global south. This is done by assessing the method’s application process of a solar startup targeting the Kenyan market - the strengths and weaknesses the company encountered during the process, measures taken by the company to overcome those weakness

In Celebrity Endorsers We Trust

Syfte: Uppsatsen avser att undersöka hur konsumenten uppfattar trovärdighet i förhållande till talespersoner i kontexten av en reklamfilm och företagets varumärke. Detta för att komma med ett teoretiskt kunskapsbidrag inom det teoretiska ämnet The Source Credibility Theory. Teoretiska perspektiv: Uppsatsen tar utgångspunkt ur The Source Credibility Theory med inriktning på The Source Credibility M