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Rationale: Atrial fibrillation causes one-fifth of ischemic strokes, with a high risk of early recurrence. Although long-term anticoagulation is highly effective for stroke prevention in atrial fibrillation, initiation after stroke is usually delayed by concerns over intracranial hemorrhage risk. Direct oral anticoagulants offer a significantly lower risk of intracranial hemorrhage than other anti

Carbohydrate deficient glycoprotein syndromes (CDG) are inherited multisystem disorders characterized by the abnormal glycosylation of a number of serum glycoproteins. CDG-Ia results from deficiency of phosphomannomutase that catalyzes the conversion of mannose-6-phosphate to mannose-1-phosphate in the cytosol. We report a case of CDG-Ia in an 11-month-old girl with developmental delay, failure to

Background: Improving stroke services is critical for reducing the global stroke burden. The World Stroke Organization–World Health Organization–Lancet Neurology Commission on Stroke conducted a survey of the status of stroke services in low and middle-income countries (LMICs) compared to high-income countries. Methods: Using a validated World Stroke Organization comprehensive questionnaire, we co

BACKGROUND: The St Gallen 2019 guidelines for primary therapy of early breast cancer recommend omission of completion axillary lymph node dissection (cALND), regardless of histological type, in patients with one or two sentinel lymph node (SLN) metastases. Concurrently, adjuvant chemotherapy is endorsed for luminal A-like disease with four or more axillary lymph node (ALN) metastases. The aim of t

The aim of this study is to explore the use and perceived unfilled need for assistive technology (AT) for everyday life in three age-groups during the ageing process. Data on use and perceived unfilled need for AT from three age-groups were used; the very old age-group; 81-90, n=314, the oldest old age-group; 85-94, n=154 and younger agegroup, 67-71. The results show that the proportion of users h

Topic-independent expressions for conveying agreement and disagreement were annotated in a corpus of web forum debates, in order to evaluate a classifier trained to detect these two categories. Among the 175 expressions annotated in the evaluation set, 163 were unique, which shows that there is large variation in expressions used. This variation might be one of the reasons why the task of automati

The discovery that variants in the melatonin receptor 2 (MTNR1B) gene were associated with glucose levels, insulin secretion, and risk for type 2 diabetes (T2D) in genome-wide association studies (GWAS) reinforced the previously suggested link between glucose homeostasis and circadian rhythmicity. Diurnal secretion of melatonin has reported to be altered in people with diabetes and rodent models o

Type 2 diabetes has become a leading health problem throughout the world. The escalating epidemic of type 2 diabetes is believed to result from a collision between inherent biological susceptibilities (genotypes) and a shift toward dietary habits and lifestyle that promote obesity over the past several decades; the transition from “traditional” to modern “obesogenic” lifestyles is characterized by

Here a synthesis of novel galactose-1,2,3-triazole conjugates is described. The title compounds were obtained from 3-azido-3-deoxy-1,2: 5,6-di-O-isopropylidene-α-D-galactofuranose via a copper catalyzed azide-alkyne 1,3-dipolar cycloaddition reaction. It was demonstrated that the title compounds in their isopropylidene-protected form tend to chelate copper. The copper content can be diminished to

Antibody-based microarrays is a novel technology with great promise for high-throughput proteomics. The process of designing high-performing arrays has, however, turned out to be challenging. Here, we have designed the next generation of a human recombinant scFv antibody microarray platform for protein expression profiling of nonfractionated biotinylated human plasma and serum proteomes. The setup

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https://www.saco.se/fortroendevald/lokalt-fackligt-arbete/lokala-akademikerforeningar/privat/akademikerforbunden/fortroendevald/ - 2026-06-07

2016| Lena Granqvist och Håkan Regnér Sifferlösa avtal och andra avtalskonstruktioner En del av akademikernas arbetsmarknad Sifferlösa avtal och andra avtalskonstruktioner En del av akademikernas arbetsmarknad Citera gärna ur skriften, men ange källa © Lena Granqvist, Håkan Regnér och Saco 2016 ISBN:978-91-88019-19-6 www.saco.se 3 Sammanfattning År 2015 täcktes 90 procent av de anställda av avtal

https://www.saco.se/globalassets/bilder-video-och-dokument/sacos-rapporter/2016/2016-sifferlosa-avtal.pdf - 2026-06-07

HAMLET, a complex of α-lactalbumin and oleic acid, preferentially kills cancer cells and is also effective in vivo. HAMLET causes apoptosis but cells die even if this pathway is inhibited. Thus, the role of autophagy, an alternative cell death pathway, was examined. During autophagy double membrane-enclosed autophagosomes form around cellular material and deliver it to the lysosomes for degradatio

Controlled vocabularies (CVs), i.e. a collection of predefined terms describing a modeling domain, used for the semantic annotation of data, and ontologies are used in structured data formats and databases to avoid inconsistencies in annotation, to have a unique (and preferably short) accession number and to give researchers and computer algorithms the possibility for more expressive semantic anno

Are voiceless approximants categorically distinct from voiceless fricatives? We address this question by means of acoustic analysis of voiceless laterals in Icelandic, Welsh, and the endangered variety Estonian Swedish. All three have a voiceless lateral functioning in contrast to a voiced lateral approximant. The analysis focused on duration – including any period of voicing (‘pre-voicing’) just

The recent progress in our work to implement salt (NaCl) as a dosemeter is presented. Laboratory investigations have indicated a linear dose response from 1 mGy to about 100 mGy and detection limits down to 0.1 mGy. Investigations in the clinic comparing TL-dosimetry in LiF and OSL in NaCl have indicated a similar dose response for the two dosemeters at different photon energies. Field studies wit

The infrared spectrum of water, isolated in inert matrices, has been studied in the interval from 60 to 4000 cm(-1). Experiments with partially deuterated water combined with DFT (density functional theory) calculations have been used to investigate the structure of matrix-isolated water tetramer. A few, strong intermolecular fundamentals of the water tetramer have been observed. Mid-infrared band