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Role of epithelial interleukin-8 (IL-8) and neutrophil IL-8 receptor A in Escherichia coli-induced transuroepithelial neutrophil migration

Escherichia coli stimulates neutrophil migration across human uroepithelial cell layers. This study investigated the role of the neutrophil chemokine interleukin-8 (IL-8) in this process. E. coli and IL-1alpha stimulated urinary tract epithelial layers to secrete IL-8 and induced transepithelial neutrophil migration. Anti-IL-8 antibody reduced neutrophil migration across epithelial cell layers, in

Living With Intestinal Failure Caused by Crohn Disease: Not Letting the Disease Conquer Life.

This article reports the findings of what it means to live with intestinal failure caused by Crohn disease and how it influences daily life. Ten patients, 7 with an ostomy and 7 on home parenteral nutrition followed up at an outpatient clinic for patients with intestinal failure, were interviewed using a qualitative, phenomenological-hermeneutic method. The analysis of the transcribed data is desc

Cytokine responses during mucosal infections: role in disease pathogenesis and host defence

Mucosal pathogens use diverse and highly specific molecular mechanisms to activate mucosal inflammation. It may even be argued that their virulence depends on the inflammatory response that they induce. Some bacteria target epithelial cells and trigger them to produce inflammatory mediators but others cross the mucosa and activate macrophages or dendritic cells. Although systemic release of inflam

Effect of maternal betamethasone on fetal and uteroplacental blood flow velocity waveforms.

Abstract OBJECTIVES: To investigate the effects of antenatal betamethasone on fetal and uteroplacental hemodynamics. METHODS: The study comprised 33 women with singleton high-risk pregnancies (23-33 weeks; 27 pregnancies < 30 weeks) not in labor, but at risk for preterm delivery based on fetal or maternal indications. They were treated with two doses of 12 mg betamethasone intramuscularly 24 h ap

14C Produced by Nuclear Power Reactors - Generation and Characterization of Gaseous, Liquid and Solid Waste

Popular Abstract in Swedish Kärnkraftverk släpper under drift ut små mängder av många olika radioaktiva ämnen. De flesta av dessa ämnen når aldrig människan. Detta beror vanligen på att de hunnit sönderfalla på vägen eller att det saknas upptagsvägar vilket betyder att de är otillgängliga för människan. Ett av undantagen är kol-14 (14C). Detta radioaktiva ämne produceras både naturligt och genom mThis thesis presents the results from studies on carbon-14 produced by nuclear power reactors. Radioactive 14C enters the carbon cycle and can be taken up by humans, where it will constitute a potential health hazard. Therefore, the main focus of this thesis was to provide new data and knowledge necessary for the implementation of appropriate nuclear waste management strategies. Such data have pre