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The purpose of this article is to discuss how the aristocracy used space and landscape to strengthen their position in society and how this process developed from the Viking Age to the Middle Ages.

Empirical research on the knowledge dynamics of biotechnology demonstrates a dual local-global knowledge flow pattern. The sector is characterised by strong spatial concentration around nodes of excellence that are interconnected through a global network. This requires a specification of the notion of proximity as a facilitator of learning processes which emphasises its multifaceted configuration.

Objective No depression rating scale has yet been designed to identify all clinically important depressive states in elderly. Therefore, this study investigated the Hopkins Symptom Checklist-25 (HSCL-25), a self-rating scale for depression, to see if it was a sensitive indicator of major, minor and subsyndromal depression. Methods Structured interviews of 37 people with a high depressive score and

The apolipoprotein (apoE) epsilon4 allele was studied in fronto-temporal dementia (FTD), a diagnostic category including the specific disorders Pick's disease and frontal lobe degeneration of non-Alzheimer type (FLD). These dementing diseases have neuronal and synaptic degeneration in common with Alzheimer's disease (AD), for which the presence of the apoE epsilon4 allele is a known risk factor, a

The resolution and fidelity of global chronostratigraphic correlation are direct functions of the time period under consideration. By virtue of deep-ocean cores and astrochronology, the Cenozoic and Mesozoic time scales carry error bars of a few thousand years (k.y.) to a few hundred k. y. In contrast, most of the Paleozoic time scale carries error bars of plus or minus a few million years (m. y.)

Background: The global gene regulator Special AT-rich sequence-binding protein1 (SATB1) has been reported to reprogramme tumour cells into a more malignant phenotype and associate with poor clinical outcome in several cancer forms. In this study, we investigated the molecular correlates and prognostic impact of SATB1 expression in human epithelial ovarian cancer (EOC). Findings: Immunohistochemica

Streamlining new product development forces companies to make decisions on preliminary information. This article considers this challenge within the context of project management in the aerospace sector and, in particular, for the development of product-service systems. The concept of knowledge maturity is explored as a means to provide practical decision support, which increases decision makers’

1. Researchers are currently placing hundreds of geolocators on migratory animals. Return rates for some small birds carrying these devices have been lower than expected, potentially because geo- locators increase drag during flight. 2. We measured the drag of three different geolocators (1 2g BAS-MK10, 1 0 g SOI-GL10 09 and 0 5 g SOI-GL05 10) in backpack-style harnesses on two preserved bird bodi

The ATLAS experiment is one of the four experiments at the Large Hadron Collider (LHC), which is supposed to be operational in early 2007. Proton-proton collisions at an unprecedented center-of-mass energy of 14 TeV will probe new frontiers of the universe, hopefully providing a better understanding of the laws governing our universe. Although the ATLAS detector has been optimized to search for th