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Cyclooxygenase-2 (COX-2) is an enzyme that has been extensively investigated as a prognostic marker in cancer. In non-small cell lung cancer (NSCLC) previous results regarding the prognostic impact of COX-2 expression are inconsistent. Therefore we evaluated the association between transcript levels and overall survival in nine publicly available gene expression data sets (total n = 1337) and dete

Objectives This study examined the validity of a common belief in epidemiology with respect to work-related musculoskeletal disorders, that individual mechanical job exposure is better estimated from tasks performed in the job than from the mean exposure of the occupational group. Methods Whole-day recordings of upper trapezius electromyography were obtained from 24 cleaners and 23 office workers.

The aim of this study was to determine therapy-related risk factors for the development of melanoma after childhood cancer. Among 4401 3-year survivors of a childhood cancer in eight French and British centres and 25 120 patients younger than 20 years old at first malignant neoplasm (FMN) extracted from the Nordic Cancer Registries, 16 patients developed a melanoma as a second malignant neoplasm (

We examined the relationship between plant species diversity, productivity and the development of the soil community during early secondary succession on former arable land across Europe. We tested the hypothesis that increasing the initial plant species diversity enhances the biomass production and consequently stimulates soil microbial biomass and abundance of soil invertebrates. We performed fi

An interference quenching of the m=1 final state vibrational line in the resonant Auger decay of N 1s-->pi(*) core-excited N-2 is observed and analyzed. The intensity ratio between the m=1 and m=0 vibrational levels of the X (2)Sigma(g)(+) final state shows a surprising nonmonotonic variation as a function of frequency detuning, going through a minimum with a complete suppression of m=1. We have d

The Formoterol and Corticosteroids Establishing Therapy (FACET) study has provided the first opportunity to examine the long-term effects of inhaled steroids and long-acting beta2-agonists on asthma-specific quality of life. The objectives of the present study were to: evaluate the effects of long-term (1 yr) formoterol and increasing doses of budesonide on asthma quality of life; 2) to determine

Photofragmentation of small argon clusters with size below ten atoms is reported. In this size range significant modifications from the electronic properties and geometry take place. When tuning the photon energy through the argon 2p edge, the fragmentation pattern is changed. Specifically, cation dimer production is enhanced at the 2p(3/2)-> 4s resonance, while above the 2p edge almost complete a

A new approach for obtaining an estimate of the effective size of the free neutral clusters is proposed. The approach relies on an experimental measure of the surface and interior or "bulk" cluster atoms provided by the x-ray photoelectron spectroscopy and on a model for the attenuation of photoelectrons ejected from the bulk of the cluster as the result of the ionizing irradiation. The experiment

Monocarboxylate transporter 8 (MCT8) is a thyroid hormone transporter, the gene of which is located on the X chromosome. We tested whether mutations in MCT8 cause severe psychomotor retardation and high serum triiodothyronine (T,) concentrations in five unrelated young boys. The coding sequence of MCT8 was analysed by PCR and direct sequencing of its six exons. In two patients, gene deletions of 2

HAMLET is the first member of a new family of tumoricidal protein-lipid complexes that kill cancer cells broadly, while sparing healthy, differentiated cells. Many and diverse tumor cell types are sensitive to the lethal effect, suggesting that HAMLET identifies and activates conserved death pathways in cancer cells. Here, we investigated the molecular basis for the difference in sensitivity betwe

BACKGROUND: The reported associations for several per- and polyfluoroalkyl substance (PFAS) with thyroid hormones are inconsistent in epidemiological studies. The purpose of the current study was to investigate the possible association of thyroid hormones in relation to serum levels of perfluorohexane sulfonate, perfluorooctane sulfonate and perfluorooctanoic acid, in a Swedish general population,

Rättighetslistan FÖR LUNDS UNIVERSITETS STUDENTER 2 Rättighetslistan för Lunds universitets studenter innehåller rättig- heter och skyldigheter som har att göra med behörighet och urval, studiemiljö, kursplaner och schema, prov och examination, examens- arbeten och kursvärdering. Syftet med listan är att underlätta för studenterna att genomföra sina studier, att tillgodose att de ska kunna få ut s

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/handbok-rattighetslistan-webb-.pdf - 2026-05-27

Bakgrund: Det är viktigt att utvärdera hörapparatsanpassning på små barn med kompletterande skattningsfrågeformulär som kan ge en mer verklighetsbaserad bild av barnets lyssnarbeteende i barnets vardagliga miljö, och hur det utvecklas över tid. Syfte: Syftet med denna studie är att validera och normera frågeformuläret Parent’s Evaluation of Aural/oral Performance of Children (PEACH Rating Scale) o

Med främsta syfte att främja kommunikationen och öka patientsäkerheten vid kirurgiska ingrepp lanserade World Health Organisation (WHO) 2008 en checklista för säker kirurgi, då många studier visade att en stor del av morbiditeten och mortaliteten vid kirurgiska ingrepp var undvikbar. I Sverige framställde Landstingens Ömsesidiga Försäkringsbolag (LÖF) 2018 en modifierad version för att bättre speg

According to the UN Convention on the Rights of the Child, Articles 19 and 34 require all States Parties to protect children against all forms of sexual exploitation and sexual abuse. According to Article 1 of the Convention, children are defined as individuals under 18 years of age. In Swedish law we find provisions that criminalize sexual offenses against children in Chapter 6 Penal Code. Many o

Uppsatsen utreder om rättsläget avseende begreppet ”sexuell handling som med hänsyn till kränkningens allvar är jämförlig med samlag” i 6 kap. 1 § 1 st. BrB är tydligt. Frågan är relevant eftersom begreppet utgör gränsdragningsrekvisitet mellan våldtäkt och andra sexualbrott och mellan våldtäkt och andra brott mot person. Lagstiftaren har medvetet utformat ett vagt gränsdragningsrekvisit med ett v

For the last 70 years the regulation of personal liability for damages regarding boards and CEO’s in their relation to their companies have not substantially changed in Swedish law. This thesis focuses on the accountability of board members and the CEO towards companies according to Chapter 29 1 § 1p. Companies Act (2055:551) (”ABL”), so-called internal liability for damages, (Sw: internt skadestå

The aminoglycosides and cyclic polypeptides are essential drugs in the treatment of multidrug-resistant tuberculosis, underscoring the need for accurate and reproducible drug susceptibility testing (DST). The epidemiological cutoff value (ECOFF) separating wild-type susceptible strains from non-wild-type strains is an important but rarely used tool for indicating susceptibility breakpoints against